Michael Chen, MD

Professor

Rush University

Affiliations

Rush Medical College

Department Of Neurological Surgery

News & Events

Rush University

Michael Chen, MD, is a Professor at Rush University. A high senior professor, he specializes in stroke, neurointerventional surgery, and cerebrovascular disease, with research spanning epidemiology, neuroradiology, and vascular surgery. His latest work focuses on endovascular thrombectomy for large-core and medium-vessel occlusions, including sex-based differences in outcomes and anesthesia effects, as published in the New England Journal of Medicine, Stroke, and Neurology. He also contributes to trials on carotid stenting and venous sinus stenting, advancing evidence for noninvasive evaluation and intensive medical therapy in stroke prevention.

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Michael Chen, MD

Rush University

Professor

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neurology stroke neurointerventional surgery cerebrovascular disease epidemiology neurosurgery vascular surgery respiratory medicine neuroradiology hematology survival analysis vascular biology emergency medicine clinical trials thrombosis cerebrovascular intervention neuroscience cardiovascular disease neurovascular diseases acute ischemic stroke brain injury endovascular techniques stroke rehabilitation endovascular thrombectomy cardiology cerebral blood flow pain management intensive care hemostasis cohort studies clinical evidence interventional neuroradiology resuscitation clinical neurosurgery arterial disease vascular disease neurorehabilitation retrospective cohort studies cardiovascular research prospective cohort studies spinal cord medicine cardiovascular surgery clinical neurology endovascular management endovascular therapy secondary analysis angiology neurotology neurologic intensive care large core stroke clinical lipidology early diagnosis interdisciplinary neurosurgery large ischemic strokes cerebral aneurysms baseline correction multi-scale studies randomized controlled trials treatment and prevention vascular trauma endovascular treatment guidelines committee clinical relevance mild strokes primary investigation field trial short-term variability key site candidate selection dimensioning and tolerancing minimally invasive procedures pipeline device prospective study intracranial aneurysms pipeline embolization device mechanical thrombectomy

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Wmp85: Site vs Core-Lab Ct Aspects Read in the Select2 Trial – Assessment of Trial Eligibility and Evt Treatment Effect. Stroke (2025)

Faisal AlshaibiDeep PujaraAmeer HassanMichael Abrahamclark sittonMuhammad HussainThanh NguyenSantiago Ortega-GutierrezMichael ChenYazid SaidiMohammed AlbedaiwiBassam YaghmoorAlhassin Al MostaneerHannah Tabitha Johnsleonid churilovMark ParsonsJames GrottaMarc RiboMichael HillBruce CampbellAmrou Sarraj

evt treatment effectmedical imagingcomputed tomographyradiologytrial eligibilitytreatment effectsclinical trialsstroke

Abstract Wp170: Association of Workflow Metrics With Functional Outcomes in the Select2 Trial. Stroke (2025)

Pascal JabbourFawaz Al-MuftiAmeer HassanMichael AbrahamShazam HussainSantiago Ortega-GutierrezMichael ChenDeep PujaraHannah Tabitha Johnsclark sittonleonid churilovMichael HillMarc RiboBruce CampbellChirag GandhiStavropoula TjoumakarisAmrou Sarraj

functional outcomeshealth sciencesstrokeworkflow metrics

Association of Ischemic Core Hypodensity With Thrombectomy Treatment Effect in Large Core Stroke: A Secondary Analysis of the Select2 Randomized Controlled Trial. Stroke (2025)

Vignan YogendrakumarBruce C.V. CampbellHannah JohnsLeonid ChurilovFelix C. NgClark W. SittonAmeer E. HassanMichael G. AbrahamSantiago Ortega‑GutierrezM. Shazam HussainMichael ChenScott E. KasnerGagan SharmaProdipta GuhaDeep K. PujaraFaris ShakerMaarten G. LansbergLawrence R. WechslerThanh N. NguyenJohanna T. FifiMichael D. HillMarc RiboMark W. ParsonsStephen M. DavisJames C. GrottaGregory W. AlbersAmrou Sarraj

prospective cohort studiesimmunologyischemic core hypodensitypharmacologyemergency medicineretrospective cohort studiesvascular biologyclinical lipidologynephrologyhematologycanadian studiesthrombectomy treatment effectlarge core strokecaesarean sectionsecondary analysisclinical evidencediabetescardiovascular researchcohort studiesturkish studiessurvival analysishypertension

Comaneci-Assisted Embolization of Wide-Necked Aneurysms: Results From the Success Postmarket Us Study. Journal of NeuroInterventional Surgery (2025)

neurologyneurointerventional surgerycomaneci-assisted embolizationvascular surgerycerebrovascular interventionwide-necked aneurysmssurgerymicrosurgeryendovascular techniquesinterventional neuroradiologymedical devicesneurosurgeryendovascular managementneurovascular diseasesbrain injurystroke

Commentary on the River Stent Trial: Venous Sinus Stenting is Safe and Effective and Can Be Fully Evaluated Using Noninvasive Methods. Journal of NeuroInterventional Surgery (2025)

Matthew Robert AmansMichael LevittJoshua A HirschJ MoccoDavid FiorellaDavid AltschulDorothea AltschulMichael ChenReade Andrew De LeacyAdam S ArthurKazim H NarsinhWaleed BrinjikjiJames M MilburnMichael G AbrahamNicholas A TelischakFerdinand Hui

immunologynoninvasive methodsneuroradiologyemergency medicinevascular biologyhematologyvenous sinus stentingriver stent trialpain managementintensive carerespiratory medicineneurologic intensive carestroke rehabilitationfield trialclinical evidenceclinical trialsstrokerehabilitationendovascular managementtreatment optionssurvival analysis

Crest-2: Percutaneous Carotid Stenting Plus Intensive Medical Therapy Reduces Stroke in Asymptomatic Patients. Journal of NeuroInterventional Surgery (2025)

E-044 Investigation Into Factors Associated With Technical Failure of Endovascular Therapy in Ischemic Stroke. (2025)

E-091 the Keep Study: Intracranial Aneurysm Embolization With I-Ed Coils Short-Term and Long-Term Clinical and Angiographic Results. (2025)

neurologyneurointerventional surgeryintracranial aneurysm embolizationi-ed coilsvascular surgerycerebrovascular interventionconcussionanesthesiologykeep studyendovascular techniquesinterventional neuroradiologyneuroradiologyneurosurgerystroke

E-280 Socioeconomic Influences on Discharge Destination After Aneurysmal Subarachnoid Hemorrhage. (2025)

Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes. Neurology (2025)

Santiago Ortega-GutierrezAaron Rodriguez-CalienesDeep PujaraClark SittonMilagros Galecio-CastilloAmeer E. HassanMichael G. AbrahamMichael ChenSpiros BlackburnScott E. KasnerHeena OlaldeMalik GhannamMuhammad S. HussainEnrique C. LeiraMario Martínez-GaldámezAmir ShabanJenny P. TsaiHannah RoederJulie C. GudenkaufRonald BudzikNirav VoraRicardo A. HanelAmin AghaebrahimFrances ColganMaria Angeles de MiquelChirag D. GandhiFawaz Al-MuftiJordi BlascoLuis San Román ManzaneraNabeel A. HerialNathan W. ManningAndrew CheungOsman KozakBernard YanPeter J. MitchellKoji EbersoleGabor TothMichael GoochDaniel GibsonDaniel H. SahleinKrishna AmuluruMohammad Ammar AbdulrazzakKelsey DuncanDana DeftaFaris ShakerFaisal Al-ShaibiAbhishek RayJeffrey SunshineYin C. HuJan Karl BurkhardtOsman MirBader AlenziTareq Kass-HoutRishi GuptaStavropoula I. TjoumakarisPascal M. JabbourThanh N. NguyenJohanna Therese FifiVitor Mendes PereiraNicholas BambakidisMichael D. HillJames C. GrottaMarc RiboBruce C.V. CampbellEdgar A. SamaniegoAmrou Sarraj

prospective cohort studiescardiovascular diseaseimmunologypharmacologylarge ischemic strokesretrospective cohort studiesvascular biologyhematologycanadian studiesintensive carecritical careclinical presentationendovascular thrombectomyearly diagnosisresuscitationcardiovascular researchcohort studiesbrain injurysurvival analysishypertension