Faculty

Institution

Unit

Venue

Melissa Petersen

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

Pharmacology and Neuroscience

School Of Public Health

Department Of Behavioral And Community Health

Department Of Behavioraland Community Health

Department Of Health Behavior And Health Systems

Department Of Population And Community Health

University of North Texas Health Science Center

Focused on Resources for her Health Education and Research (FOR HER)

Osteopathic Research Center (ORC)

Melissa Petersen is a Senior Professor at the University of North Texas Health Science Center. Her research focuses on the neuroscience of aging, Alzheimer’s disease, and neurodegenerative diseases, with a particular emphasis on biomarkers for cognitive impairment and dementia. She leads the Health and Aging Brain Study–Health Disparities (HABS-HD), investigating racial and ethnically diverse community cohorts. Her recent work includes precision medicine for Alzheimer’s disease in Down syndrome, plasma AT(N) biomarker characterization, and the Alzheimer’s Biomarker Consortium–Down Syndrome (ABC-DS) 10-year report.

Honors

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Experiences

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Education

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Melissa Petersen

University of North Texas Health Science Center

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alzheimer's disease neuroscience neurology cognitive impairment dementia neuroscience of aging neurodegenerative diseases health sciences geriatrics biomarkers aging-associated diseases molecular neurodegeneration public health geriatric neurology neurochemical biomarkers cognitive neuroscience mexican americans experimental gerontology down syndrome neuropsychology vascular dementia non-hispanic whites plasma biomarkers psychiatric research disease assessment brain health brain pathology neuroimaging biomarkers vascular cognitive disorder cerebrovascular disease mild cognitive impairment habs-hd study biological psychiatry affective disorders clinical gerontology cohort studies geriatric medicine biomarker (medicine) biomedical informatics medicinal research experimental medicine clinical proteomics cross-sectional studies precision medicine healthy aging biomarker discovery cross-sectional studies hable study disease biomarkers alzheimer ’ machine learning research biomedical analysis neuroradiology social gerontology underserved populations brain function prognostic biomarkers connectomics latino elders neuropsychological test performance respiratory medicine computational intelligence proteome research clinical neurology hyperparameter estimation parameter tuning elderly care cancer biology community-dwelling mexican americans brain amyloid diverse community-based cohort epidemiologic research cancer management cancer genomics disease risk assessment participant characteristics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Contextual Variability in Under-Diagnosed Cardiometabolic Disease and Cognitive Vulnerability Among Populations at High Risk for Alzheimer’s Disease and Related Dementias. Research Square (2026)

neurologyvascular dementiaexperimental gerontologyhigh riskaging-associated diseasescognitive vulnerabilityepidemiologydementiacognitive impairmentalzheimer's diseasecontextual variabilityneuroscience of agingneurodegenerative diseases

Precision Medicine for Alzheimer's Disease in Down Syndrome. Alzheimer s & Dementia (2026)

neurologyneurochemical biomarkerstranslational psychiatrycognitive impairmentmolecular neurodegenerationdown syndromealzheimer's diseaseneuroscienceneurodegenerative diseases

A Comparison of Multiple Amyloid Pet Radiotracers for Down Syndrome Clinical Trials. Brain Communications (2025)

neurologyradiologyneuroimaging biomarkersneuroimagingneuroradiologycognitive impairmentneuroscience of agingneuroscienceneurodegenerative diseases

Alzheimer's Disease Diagnostic Progression is Associated With Cerebrovascular Disease and Neuroinflammation in Adults With Down Syndrome. Alzheimer s & Dementia (2025)

neurologyvascular dementiabrain pathologycerebrovascular diseasevascular cognitive disorderneuroimmunologydisease diagnostic progressiondementiacognitive impairmentmolecular neurodegenerationneuroscience of agingdown syndromealzheimer's diseaseneuroscienceneurodegenerative diseases

Alzheimer's Disease Plasma Biomarkers and Physical Functioning in a Diverse Sample of Adults. Alzheimer s & Dementia (2025)

neurologyexperimental gerontologybiomarkersaging-associated diseasesphysical functioningneurochemical biomarkerscognitive impairmentneuroscience of agingdiverse samplealzheimer's diseaseneuroscienceneurodegenerative diseasesdisease plasma biomarkers

Association of Alzheimer’s Disease Biomarkers With Low Premorbid Intellectual Functioning in a Multi-Ethnic Community-Dwelling Cohort: A Cross-Sectional Study of Habs-Hd. Journal of Alzheimer s Disease (2025)

neurologyvascular dementiamulti-ethnic community-dwelling cohortdisease biomarkersintellectual disabilitypsychiatric researchpsychiatrycross-sectional studiescognitive impairmentneuroscience of agingneurodevelopmental disordersalzheimer's diseasegeriatric neurologyneuroscienceneurodegenerative diseases

Cerebrovascular Disease and Neuroinflammation Predict Change in Alzheimer's Disease Plasma Biomarkers in Adults With Down Syndrome. Alzheimer s & Dementia (2025)

neurologyvascular dementiabrain pathologycerebrovascular diseasevascular cognitive disorderaging-associated diseasesneuroimmunologyneurochemical biomarkersdown syndromemolecular neurodegenerationcerebral blood flowalzheimer's diseaseneuroscienceneurodegenerative diseasesdisease plasma biomarkers

Characterization of Plasma at(N) Biomarkers Among a Racial and Ethnically Diverse Community‐Based Cohort: An Habs‐Hd Study. Alzheimer s & Dementia Translational Research & Clinical Interventions (2025)

Melissa E. PetersenFan ZhangJames HallCourtney BrockRobert A. RissmanTori ComoDavid JulovichMark MapstoneBeau M. AncesKarin MeekerRaymond PalmerRobert BarberDavid MasonLeigh JohnsonKristine YaffeArthur W. TogaAnnie CohenSid E. O'Bryant

biomarkerstranslational researchhabs-hd studybiostatisticsclinical researchdementiadiverse community-based cohortalzheimer's diseasecohort studies

Chronic Emotional Stress and Mediating Role of Interleukin-6 in the Association With Cardiometabolic Disorders in a Multiethnic Middle-Aged and Older Us Population. International Journal of Cardiology Cardiovascular Risk and Prevention (2025)

cardiometabolic disordersmental healtholder us populationstress biomarkerspsychologypsychiatrychronic emotional stressaffective disordersstress (biology)psychoneuroimmunologypsychological medicinehealth sciences

Correlating Hippocampal and Amygdala Volumes With Neuropathological Burden in Down Syndrome and Alzheimer’s Disease and Related Neurodegenerative Pathologies Using 7T Postmortem Mri. Journal of Neuropathology & Experimental Neurology (2025)

Jr-Jiun LiouJinghang LiJacob BerardinelliHecheng JinTales SantiniJaehoon NohNadim FarhatMinjie WuHoward J AizensteinJoseph M MettenburgWilliam H YongElizabeth HeadMilos D IkonomovicTamer S IbrahimJulia K KoflerBeau M AncesHoward F AndrewsKaren BellRasmus M BirnAdam M BrickmanPeter BulovaAmrita CheemaKewei ChenBradley T ChristianIsabel ClareLorraine ClarkAnn D CohenJohn N ConstantinoEric W DoranAnne FaganEleanor FeingoldTatiana M ForoudBenjamin L HandenSigan L HartleyRachel HensonChristy HomLawrence HonigSterling C JohnsonCourtney JordanM Ilyas KambohDavid KeatorWilliam E KlunkWilliam Charles KreislSharon J Krinsky-McHaleFlorence LaiPatrick LaoCharles LaymonJoseph Hyungwoo LeeIra T LottVictoria LupsonMark MapstoneChester A MathisDavneet Singh MinhasNeelesh NadkarniSid O'BryantDeborah PangMelissa PetersenJulie C PriceMargaret PulsiferMichael RafiiEric ReimanBatool RizviHerminia Diana RosasMarwan N SabbaghNicole SchupfWayne P SilvermanDana L TudorascuRameshwari TumuluruBenjamin TyckoBadri VaradarajanDesiree A WhiteMichael A YassaShahid ZamanFan Zhang

neurologyneuropathological burdenpostmortem mrineuroimagingneuropathologyexperimental neuropathologydown syndromeamygdala volumesalzheimer's diseaseneurodegenerative diseasesrelated neurodegenerative pathologies

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Melissa Petersen

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

Pharmacology and Neuroscience

School Of Public Health

Department Of Behavioral And Community Health

Department Of Behavioraland Community Health

Department Of Health Behavior And Health Systems

Department Of Population And Community Health

University of North Texas Health Science Center

Focused on Resources for her Health Education and Research (FOR HER)

Osteopathic Research Center (ORC)

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Melissa Petersen

University of North Texas Health Science Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Contextual Variability in Under-Diagnosed Cardiometabolic Disease and Cognitive Vulnerability Among Populations at High Risk for Alzheimer’s Disease and Related Dementias. Research Square (2026)

Precision Medicine for Alzheimer's Disease in Down Syndrome. Alzheimer s & Dementia (2026)

neurologyneurochemical biomarkerstranslational psychiatrycognitive impairmentmolecular neurodegenerationdown syndromealzheimer's diseaseneuroscienceneurodegenerative diseases

A Comparison of Multiple Amyloid Pet Radiotracers for Down Syndrome Clinical Trials. Brain Communications (2025)

neurologyradiologyneuroimaging biomarkersneuroimagingneuroradiologycognitive impairmentneuroscience of agingneuroscienceneurodegenerative diseases

Alzheimer's Disease Diagnostic Progression is Associated With Cerebrovascular Disease and Neuroinflammation in Adults With Down Syndrome. Alzheimer s & Dementia (2025)

Alzheimer's Disease Plasma Biomarkers and Physical Functioning in a Diverse Sample of Adults. Alzheimer s & Dementia (2025)

Cerebrovascular Disease and Neuroinflammation Predict Change in Alzheimer's Disease Plasma Biomarkers in Adults With Down Syndrome. Alzheimer s & Dementia (2025)

biomarkerstranslational researchhabs-hd studybiostatisticsclinical researchdementiadiverse community-based cohortalzheimer's diseasecohort studies

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