Melissa P Mitchell, MD, PhD

Melissa P. Mitchell, MD, PhD, is an Associate Professor in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center. Her research focuses on optimizing radiation therapy and surgical de-escalation for breast cancer, including the selective elimination of breast surgery and sentinel lymph node biopsy in early-stage disease. She leads the NRG-BR008/HERO Phase III trial on radiotherapy optimization for low-risk HER2-positive breast cancer and investigates oncoplastic reconstruction, MRI-conditional tissue expanders, and treatment-related toxicities such as pneumonitis from trastuzumab deruxtecan. Her work has appeared in JAMA Oncology, Cancer, and Breast Cancer Research.