Faculty

Institution

Unit

Venue

Matthew Rodeheffer

Professor of Comparative Medicine

Yale University

Affiliations

Cellular & Molecular Physiology

Matthew Rodeheffer is currently serving as a Cellular & Molecular Physiology Professor of Comparative Medicine at Yale University.

Honors

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Experiences

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Education

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Matthew Rodeheffer

Yale University

Professor of Comparative Medicine

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physiology cell biology obesity health sciences liver physiology developmental biology membrane biology endocrinology cellular physiology regenerative medicine cellular biology cell metabolism metabolism stem cell research gene expression stem cells human biology bone research mammalian biology tissue physiology mitochondrial function cutaneous biology vascular biology molecular physiology genome biology molecular cell biology bone metabolism cell physiology cell regulation metabolic regulation protein science comparative endocrinology endocrine research yeast tissue development adipocyte precursors adipose tissue neuroscience of aging nature biomedical imaging cell research fungal genetics cell lineage biogerontology chronic inflammation tissue imaging molecular regulation human tissues developmental genetics cell fate determination protein expression rna biology gene regulation appetite control gene networks renal function human-environment interactions catabolism geriatric endocrinology cell biomechanics catalyst activation biomedical data analysis bone imaging adipocyte lineage cells adipocyte cellular lineage inflammasome-driven catecholamine catabolism marrow fat rapid depot-specific activation adipocyte precursor cells adipose tissue microenvironment depot-specific adipogenesis cre recombinase models bone marrow adipocytes human adipose tissues clinical implications bone marrow adiposity

Notable Scholarly Works

Notable Federal Grants

Collaborators

Comparative Single-Cell Lineage Tracing Identifies Distinct Adipocyte Precursor Dynamics in Skin and Inguinal Fat. Cell stem cell (2025)

cell fate determinationcellular physiologydevelopmental cellcell researchinguinal fatmorphogenesiscell lineagecomparative single-cell lineagecell specializationdevelopmental biologycellular differentiationcell biology

Dietary Oleic Acid Drives Obesogenic Adipogenesis via Modulation of Lxrα Signaling. Cell Reports (2025)

physiologyobesity medicinemetabolic regulationlipidsmetabolic syndromefunctional foodslipid synthesisobesitylipid nutritionmetabolic healthdrives obesogenic adipogenesisnutritional biochemistrymetabolismnutritionbiochemistrycell metabolism

Diet-Induced Phospholipid Remodeling Dictates Ferroptosis Sensitivity and Tumorigenesis in the Pancreas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Christian Felipe RuizXiangyu GeRylee McDonnellSherry S. AgabitiDaniel C. McQuaidAndy TangMeera KharwaJennifer GoodellRocio del M. Saavedra-PenaAllison WingGuangtao LiNatasha Pinto MedicineMarie E. RobertRohan R. VarshneyMichael C. RudolphFred S. GorelickJohn J. WysolmerskiDaniel CanalsJohn HaleyMatthew S. RodehefferMandar Deepak Muzumdar

lipidsmolecular biology

Ets Emerges to Heat Up Adipose. Genes & Development (2025)

physiologyenergy transformationenergy metabolismmetabolic regulationtranslational physiologyobesitymetabolismcell metabolism

Abstract Pr-06: Dietary Fats Dictate Pancreatic Cancer Fate via Phospholipid Saturation. Cancer Research (2024)

Christian F RuizXiangyu GeRylee McDonnellDaniel McQuaidJennifer KaplanGuangtao LiMichael C RudolphFred F GorelickJohn WysolmerskiDaniel CanalsJohn D HaleyMatthew RodehefferMandar D Muzumdar

cancer researchpancreatic cancerdietary fatspancreatic cancer fatephospholipid saturation

Estradiol Cycling Drives Female Obesogenic Adipocyte Hyperplasia. Cell Reports (2023)

Rocío del M. Saavedra-PeñaNatalia TaylorClare FlanneryMatthew S. Rodeheffer

physiologyliver physiologycellular physiologyendocrinologyvascular biologyobesitycell physiologymembrane biologyhealth scienceswomen's healthcell biology

Obesogens and Obesity: State-Of-The-Science and Future Directions Summary From a Healthy Environment and Endocrine Disruptors Strategies Workshop. American Journal of Clinical Nutrition (2023)

Jerrold J. HeindelJessica A. AlvarezElla AtlasMatthew C. CaveVaia Lida ChatziDavid CollierBarbara CorkeyDouglas FischerMichael I. GoranSarah HowardScott KahanMatthias KayhoeSuneil KoliwadCatherine M. KotzMichele La MerrillTim LobsteinCarey LumengDavid S. LudwigRobert H. LustigPete MyersAngel NadalLeonardo TrasandeLeanne M. RedmanMatthew S. RodehefferRobert M. SargisJacqueline M. StephensThomas R. ZieglerBruce Blumberg

public healthendocrine disruptors strategiesbenchmark studiesenvironmental healthhealthy environmentobesityendocrine disruptorsglobal healthclinical nutritionfuture directionshealth sciences

Total Daily Energy Expenditure Has Declined Over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure. Nature Metabolism (2023)

John R. SpeakmanJasper M. A. de JongSrishti SinhaKlaas R. WesterterpYosuke YamadaHiroyuki SagayamaPhilip N. AinslieLiam J. AndersonLenore ArabKweku Bedu-AddoStephane BlancAlberto G. BonomiPascal BovetSoren BrageMaciej S. BuchowskiNancy F. ButteStefan G.J.A. CampsJamie A. CooperRichard CooperSai Krupa DasPeter S. W. DaviesLara R. DugasUlf EkelundSonja EntringerTerrence ForresterBarry W. FudgeMelanie GillinghamSantu GhoshAnnelies H. GorisMichael GurvenLewis G. HalseyCatherine HamblyHinke H. HaismaDaniel HoffmanSumei HuAnnemiek M. JoosenJennifer L. KaplanPeter KatzmarzykWilliam E. KrausRobert F. KushnerWilliam R. LeonardMarie LöfCorby K. MartinEric MatsikoAnine C. MedinErwin P. MeijerMarian L. NeuhouserTheresa A. NicklasRobert M. OjiamboKirsi H. PietiläinenJacob Plange-RhuleGuy PlasquiRoss L. PrenticeSusan B. RacetteDavid A. RaichlenEric RavussinLeanne M. RedmanSusan B. RobertsMichael C. RudolphLuis B. SardinhaAlbertine J. SchuitAnaliza M. SilvaEric SticeSamuel S. UrlacherGiulio ValentiLudo M. Van EttenEdgar A. Van MilBrian M. WoodJack A. YanovskiTsukasa YoshidaXueying ZhangAlexia J. Murphy-AlfordCornelia U. LoechlAnura KurpadAmy H. LukeHerman PontzerMatthew S. RodehefferJennifer RoodDale A. SchoellerWilliam W. Wong

physiologyactivity expenditureobesitybasal expenditurehealth sciences

Abstract Pr015: Excess Dietary Oleic Acid Primes the Pancreas for Cancer. Cancer Research (2022)

Christian F. RuizRylee McDonnellJennifer KaplanJasper de JongChristine ShugrueMichael C. RudolphFred S. GorelickJohn WysolmerskiMatthew RodehefferMandar D. Muzumdar

digestive diseasesdermatologytumor targetingpharmacologycancer carecancer managementcancer researchpancreatic cancersurvival analysisgeneticsoncologygastroenterologyclinical researchmedicinal researchclinical nutritionnutritional biochemistrycancer biologycancer treatment

Insights of the Role of Estrogen in Obesity From Two Models of Erα Deletion. bioRxiv (Cold Spring Harbor Laboratory) (2022)

physiologyobesity medicineendocrine mechanismsendocrinologyobesityweight disordershormonal receptormetabolismerα deletiongynecologyhealth sciencessteroid metabolismovarian hormones

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Matthew Rodeheffer

Professor of Comparative Medicine

Yale University

Affiliations

Cellular & Molecular Physiology

Matthew Rodeheffer is currently serving as a Cellular & Molecular Physiology Professor of Comparative Medicine at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Matthew Rodeheffer

Yale University

Professor of Comparative Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Comparative Single-Cell Lineage Tracing Identifies Distinct Adipocyte Precursor Dynamics in Skin and Inguinal Fat. Cell stem cell (2025)

Dietary Oleic Acid Drives Obesogenic Adipogenesis via Modulation of Lxrα Signaling. Cell Reports (2025)

Diet-Induced Phospholipid Remodeling Dictates Ferroptosis Sensitivity and Tumorigenesis in the Pancreas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

lipidsmolecular biology

Ets Emerges to Heat Up Adipose. Genes & Development (2025)

physiologyenergy transformationenergy metabolismmetabolic regulationtranslational physiologyobesitymetabolismcell metabolism

Abstract Pr-06: Dietary Fats Dictate Pancreatic Cancer Fate via Phospholipid Saturation. Cancer Research (2024)

Christian F RuizXiangyu GeRylee McDonnellDaniel McQuaidJennifer KaplanGuangtao LiMichael C RudolphFred F GorelickJohn WysolmerskiDaniel CanalsJohn D HaleyMatthew RodehefferMandar D Muzumdar

cancer researchpancreatic cancerdietary fatspancreatic cancer fatephospholipid saturation

Estradiol Cycling Drives Female Obesogenic Adipocyte Hyperplasia. Cell Reports (2023)

Rocío del M. Saavedra-PeñaNatalia TaylorClare FlanneryMatthew S. Rodeheffer

physiologyliver physiologycellular physiologyendocrinologyvascular biologyobesitycell physiologymembrane biologyhealth scienceswomen's healthcell biology

Obesogens and Obesity: State-Of-The-Science and Future Directions Summary From a Healthy Environment and Endocrine Disruptors Strategies Workshop. American Journal of Clinical Nutrition (2023)

public healthendocrine disruptors strategiesbenchmark studiesenvironmental healthhealthy environmentobesityendocrine disruptorsglobal healthclinical nutritionfuture directionshealth sciences

Total Daily Energy Expenditure Has Declined Over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure. Nature Metabolism (2023)

physiologyactivity expenditureobesitybasal expenditurehealth sciences

Abstract Pr015: Excess Dietary Oleic Acid Primes the Pancreas for Cancer. Cancer Research (2022)

Christian F. RuizRylee McDonnellJennifer KaplanJasper de JongChristine ShugrueMichael C. RudolphFred S. GorelickJohn WysolmerskiMatthew RodehefferMandar D. Muzumdar

Insights of the Role of Estrogen in Obesity From Two Models of Erα Deletion. bioRxiv (Cold Spring Harbor Laboratory) (2022)

physiologyobesity medicineendocrine mechanismsendocrinologyobesityweight disordershormonal receptormetabolismerα deletiongynecologyhealth sciencessteroid metabolismovarian hormones

1
2
3
4
5
6
7
10 / page

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