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Institution

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Matthew H. Sazinsky

Professor of Chemistry

Pomona College

Affiliations

Chemistry

Pomona College

Department Of Biology

Department Of Chemistry

Matthew H. Sazinsky is currently serving as a Chemistry Professor of Chemistry at Pomona College.

Honors

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Experiences

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Education

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Matthew H. Sazinsky

Pomona College

Professor of Chemistry

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biochemistry enzymes molecular biology structural biology protein structure protein science structural molecular biology enzyme catalysis biological chemistry biomolecular structure microbiology biochemical sciences structure-function enzyme kinetics biophysics chemical biology redox biology protein chemistry membrane biology crystallography enzyme inhibition protein x-ray crystallography bioenergetics biological inorganic chemistry biosynthesis molecular metabolism metalloproteins cellular enzymology microbial physiology membrane proteins coordination chemistry transition metal chemistry aldo-keto reductase biocatalysis atp hydrolysis methane monooxygenase dioxygen activation cryoem structure novosphingobium sp molecular science protein transport enzyme specificity trace elements redox chemistry biochemical genetics protein assembly biomolecular interactions natural competence sustainable chemistry energy chemistry metals structural chemistry protein phosphorylation elemental metal trace metals protein function structural composition x-ray diffraction x-ray crystallography proton transfer redox signaling pathway engineering pathway analysis molecular pathways protein biosynthesis electron paramagnetic resonance surface reactivity dioxygen-activating copper enzymes heavy metal atp binding product bound structures protein motion functionalizing methane x-ray structure hydroxylase-regulatory protein complex styrene monooxygenase reductase fad-transfer reaction

Notable Scholarly Works

Notable Federal Grants

Collaborators

ASPRED: Identification of Antigen Apecific B-Cell Receptors From Single V(D)J Sequences Using Large Language Models 4171. The Journal of Immunology (2025)

molecular immunologycomputational biologyimmunologycell biologyimmune responsemolecular informaticssingle vadaptive immune systemantigen processingcell researchreceptor

Fine-Tuned Protein Language Model Identifies Antigen-Specific B Cell Receptors From Immune Repertoires. bioRxiv (Cold Spring Harbor Laboratory) (2025)

molecular immunologysystem immunologyimmunologycellular therapyimmune responsesimmunity (medicine)antigen processinghumoral responseadaptive immune systemsystems biologycell researchreceptorsimmune repertoires

Impact of Single Point Mutations in the Sars-Cov-2 Spike Protein Rbd on B-Cell Receptor Diversity and Cross-Reactivity 4525. The Journal of Immunology (2025)

b-cell receptor diversityviral pathogenesisvirologyimmunologycell biologysars-cov-2single point mutationscross-reactivity 4525medical virologygeneral virologyreceptorsviral structural proteinvirus research

Nicotinic Acetylcholine Receptors Function With Adhesion Molecule Sax-7 to Reverse Cell Orientation During Migration. Developmental Biology (2025)

biophysicscell orientationcell interactionsadhesion molecule sax-7neuronscell biologycellular physiologycell traffickingreceptor (biochemistry)developmental biologynicotinic acetylcholine receptorsmolecular cell biologycell adhesionreceptors

Structural and Kinetic Characterization of Hyperthermophilic Nadh-Dependent Persulfide Reductase From Archaeoglobus Fulgidus. Archaea (2021)

archaeoglobus fulgidusenzymeskinetic characterizationenzyme catalysisbiochemistrybioenergeticsbiochemical sciencesmolecular biologystructure-function enzyme kineticsprotein structure

Cryoem Structure of the Type Iva Pilus Secretin Required for Natural Competence in Vibrio Cholerae. Nature Communications (2020)

Sara J. WeaverDavi R. OrtegaMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

cryoem structureprotein structurenatural competencemicrobiologybiologymolecular biologyvibrio cholerae

Cryoem Structure of the Vibrio Cholerae Type IV Competence Pilus Secretin Pilq. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Sara J. WeaverMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

cryoem structuremicrobiologymolecular biologyprotein structurestructural biology

Crystal Structures and Directed Evolution of the α‐L Rhamnosidase Rha‐P From Novosphingobium Sp. Pp1y. The FASEB Journal (2020)

chemical sciencesα‐l rhamnosidase rha‐pprotein x-ray crystallographyenzyme catalysisbiomolecular structuredirected evolutionstructural biologycrystallographybiochemistrybiomolecular structure predictionchemical biologyprotein structurenovosphingobium spstructural molecular biologybiomolecular engineering

Publisher Correction: Cryoem Structure of the Type Iva Pilus Secretin Required for Natural Competence in Vibrio Cholera. Nature Communications (2020)

Sara J. WeaverDavi R. OrtegaMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

public healthcryoem structurescientific communicationvibrio cholerainfectious diseasesnatural competencemass communicationpublisher correctionhealth sciences

Single Particle Cryoem Structure of V. Cholerae Type IV Competence Pilus Secretin Pilq. (2020)

biomolecular structuremicroorganismsprotein secretionultrastructuremicrobiologybacteriavirulence factorsmolecular biologyprotein structurestructural molecular biologystructural biology

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Matthew H. Sazinsky

Professor of Chemistry

Pomona College

Affiliations

Chemistry

Pomona College

Department Of Biology

Department Of Chemistry

Matthew H. Sazinsky is currently serving as a Chemistry Professor of Chemistry at Pomona College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Matthew H. Sazinsky

Pomona College

Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

ASPRED: Identification of Antigen Apecific B-Cell Receptors From Single V(D)J Sequences Using Large Language Models 4171. The Journal of Immunology (2025)

molecular immunologycomputational biologyimmunologycell biologyimmune responsemolecular informaticssingle vadaptive immune systemantigen processingcell researchreceptor

Fine-Tuned Protein Language Model Identifies Antigen-Specific B Cell Receptors From Immune Repertoires. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Impact of Single Point Mutations in the Sars-Cov-2 Spike Protein Rbd on B-Cell Receptor Diversity and Cross-Reactivity 4525. The Journal of Immunology (2025)

Nicotinic Acetylcholine Receptors Function With Adhesion Molecule Sax-7 to Reverse Cell Orientation During Migration. Developmental Biology (2025)

Structural and Kinetic Characterization of Hyperthermophilic Nadh-Dependent Persulfide Reductase From Archaeoglobus Fulgidus. Archaea (2021)

archaeoglobus fulgidusenzymeskinetic characterizationenzyme catalysisbiochemistrybioenergeticsbiochemical sciencesmolecular biologystructure-function enzyme kineticsprotein structure

Cryoem Structure of the Type Iva Pilus Secretin Required for Natural Competence in Vibrio Cholerae. Nature Communications (2020)

Sara J. WeaverDavi R. OrtegaMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

cryoem structureprotein structurenatural competencemicrobiologybiologymolecular biologyvibrio cholerae

Cryoem Structure of the Vibrio Cholerae Type IV Competence Pilus Secretin Pilq. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Sara J. WeaverMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

cryoem structuremicrobiologymolecular biologyprotein structurestructural biology

Crystal Structures and Directed Evolution of the α‐L Rhamnosidase Rha‐P From Novosphingobium Sp. Pp1y. The FASEB Journal (2020)

Publisher Correction: Cryoem Structure of the Type Iva Pilus Secretin Required for Natural Competence in Vibrio Cholera. Nature Communications (2020)

Sara J. WeaverDavi R. OrtegaMatthew H. SazinskyTriana N. DaliaAnkur B. DaliaGrant J. Jensen

public healthcryoem structurescientific communicationvibrio cholerainfectious diseasesnatural competencemass communicationpublisher correctionhealth sciences

Single Particle Cryoem Structure of V. Cholerae Type IV Competence Pilus Secretin Pilq. (2020)

biomolecular structuremicroorganismsprotein secretionultrastructuremicrobiologybacteriavirulence factorsmolecular biologyprotein structurestructural molecular biologystructural biology

1
2
3
4
5
6
10 / page