Faculty

Institution

Unit

Venue

Masaru Kubota

Assistant Professor at the Columbia University Medical Center

Columbia University

Affiliations

Columbia University

P&S

P&S Clinical

SRG Liver

Masaru Kubota is an Assistant Professor of Surgery at Columbia University Irving Medical Center. He earned his MD from Kansai Medical University, completed his residency at Osaka National Hospital, and received his PhD from Osaka University. His research focuses on human T cell compartmentalization, tissue-resident memory T cell aging and turnover, and the transcriptional control of T cell tissue adaptation across the lifespan. His recent work includes a 2025 study in *Immunity* on asynchronous aging of circulating and tissue-resident memory T cells, alongside publications in *Science Immunology* on γδ T cell maturation dynamics. He has also developed machine-learning models to reduce futile procurements in liver transplantation, published in *The Lancet Digital Health*.

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Masaru Kubota

Columbia University

Assistant Professor at the Columbia University Medical Center

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immunology immune responses cell biology adaptive immune system cellular immune responses developmental biology dermatology tissue (biology) immunological memory virology respiratory medicine developmental immunology t-regulatory cell veterinary medicine ageing immunity (medicine) experimental gerontology lymphocyte development barrier sites human biology inflammation cell research medicinal research nature aging cell cell transplantation mammalian biology liver transplantation clinical transplantation pediatric transplantation tissue development mucosal immunology clinical immunology virus-host interactions innate lymphoid cells dynamic establishment cellular therapy early childhood early childhood development molecular physiology medical systems innate immune system cell regulation human memory brain-immune interaction human tissues theriogenology pulmonary diseases lymphatic system particulate matter aging process fibrosis biogerontology treatment development functional regulation disease risk assessment antiviral responses viral persistence vaccine research human retrovirus host specificity germ cell fate histocompatibility influenza virus lung-tissue homeostasis human circulating lymphoid-resident commensal bacteria anatomical containment spatial map tissue determinants early-life compartmentalization lymphoid tissues regulatory function tissue-localized immunological memory tissue adaptation clonal segregation pancreatitis organ transplantation medicine graft survival oncology surgery transplant surgery hepatobiliary tumors transplantation proceeding hepatology translational medicine radiation oncology bone marrow transplantation hematology surgical oncology solid organ transplantation translational research transplantation medicine

Notable Scholarly Works

Notable Federal Grants

Collaborators

Asynchronous Aging and Turnover of Human Circulating and Tissue-Resident Memory T Cells Across Sites. Immunity (2025)

immunity (medicine)adaptive immune systemaging cellimmunologyimmune responsesimmunological memory

Development and Validation of a Machine Learning Model to Reduce Futile Donation After Circulatory Death Procurements in Liver Transplantation: A National Multi-Center Study of 2,211 Potential Donors. SSRN Electronic Journal (2025)

hepatologydigital medicinehepatitisclinical transplantationtransplant infectious diseasesmedicineliver transplantationtransplantation proceedingcritical careorgan transplantationbiostatisticssurvival analysispredictive analyticsmortalitypersonalized medicinebone marrow transplantationpediatric transplantation

Development and Validation of a Machine-Learning Model to Reduce Futile Procurements in Donations After Circulatory Death in Liver Transplantation in the USA: A Multicentre Study. The Lancet Digital Health (2025)

hepatologyoutcomes researchdigital medicinemedical systemsclinical transplantationtransplant infectious diseasesmedicineliver transplantationtransplantation proceedinghealth policyorgan transplantationcritical caresurvival analysispredictive analyticsmortalitypersonalized medicinepediatric transplantation

Transcriptional Control of T Cell Tissue Adaptation and Effector Function in Infants and Adults. bioRxiv (Cold Spring Harbor Laboratory) (2025)

cellular immune responsesgene expressionadaptive immune systemtranscription factorscell researchimmunologyimmune responsesdevelopmental immunology

Dynamic Establishment and Maintenance of the Human Intestinal B Cell Population and Repertoire Following Transplantation in a Pediatric-Dominated Cohort. Frontiers in Immunology (2024)

Jianing FuThomas HsiaoElizabeth WaffarnWenzhao MengKatherine D. LongKristjana FrangajRebecca JonesAlaka GorurAreen ShteweMuyang LiConstanza Bay MuntnichKortney RogersWenyu JiaoMonica VelascoRei MatsumotoMasaru KubotaSteven WellsNichole DanzlShilpa RavellaAlina IugaElena-Rodica VasilescuAdam GriesemerJoshua WeinerDonna L. FarberEline T. Luning PrakMercedes MartinezTomoaki KatoUri HershbergMegan Sykes

organ transplantationpediatricscell transplantationdevelopmental biologyimmunologypediatric-dominated cohortdevelopmental immunologyregenerative medicinedynamic establishment

Human γδ T Cells in Diverse Tissues Exhibit Site-Specific Maturation Dynamics Across the Life Span. Science Immunology (2024)

Joshua I. GrayDaniel P. CaronSteven B. WellsRebecca GuyerPeter SzaboDaniel RainbowCan ErgenKsenia RybkinaMarissa C. BradleyRei MatsumotoKalpana PetheMasaru KubotaSarah TeichmannJoanne JonesNir YosefMark AtkinsonMaigan BruskoTodd M. BruskoThomas J. ConnorsPeter A. SimsDonna L. Farber

experimental gerontologyhuman geneticsadaptive immune systemhealth scienceslife spandiverse tissueshuman biologyimmunologydermatologyimmune responsessite-specific maturation dynamics

Maintenance and Functional Regulation of Immune Memory to Covid-19 Vaccines in Tissues. Immunity (2024)

Julia Davis-PoradaAlex B. GeorgeNora LamDaniel P. CaronJoshua I. GrayJenny HuangJennifer HwuSteven B. WellsRei MatsumotoMasaru KubotaYoonSeung LeeRory Morrison-ColvinIsaac J. JensenBasak B. UralNamir ShaabaniDaniela WeiskopfAlba GrifoniAlessandro SettePeter A. SzaboJohn R. TeijaroPeter A. SimsDonna L. Farber

immunity (medicine)vaccinescovid-19immune memoryimmunologyfunctional regulationimmune responsesvaccinationimmunological memory

Multimodal Profiling Reveals Tissue-Directed Signatures of Human Immune Cells Altered With Age. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Steven B. WellsDaniel B. RainbowMichal MarkPeter A. SzaboCan ErgenAna Raquel MaceirasDaniel P. CaronElior RahmaniEli BenuckValeh Valiollah Pour AmiriDavid ChenAllon WagnerSarah K. HowlettLorna B. JarvisKaren L. EllisMasaru KubotaRei MatsumotoKrishnaa MahbubaniKouresh Saeb-ParsyCecilia Dominguez-CondeLaura RichardsonChuan XuShuang LiLira MamanovaLiam BoltAlicja WilkSarah A. TeichmannDonna L. FarberPeter A. SimsJoanne L. JonesNir Yosef

cell biologyhuman immune cellsimmunologyageing

Dynamic Establishment and Maintenance of the Human Intestinal B Cell Population and Repertoire Following Transplantation. medRxiv (2023)

health sciencesmedicinecell transplantationimmunologyregenerative medicinedynamic establishment

Site-Specific Development and Progressive Maturation of Human Tissue-Resident Memory T Cells Over Infancy and Childhood. Immunity (2023)

Thomas J. ConnorsRei MatsumotoShivali VermaPeter A. SzaboRebecca GuyerJoshua GrayZicheng WangPuspa ThapaPranay DograMaya M.L. PoonKsenia RybkinaMarissa C. BradleyEmma IdzikowskiJames McNicholsMasaru KubotaKalpana PetheYufeng ShenMark A. AtkinsonMaigan BruskoTodd M. BruskoAndrew J. YatesPeter A. SimsDonna L. Farber

lymphocyte developmentadaptive immune systemimmune responsestissue (biology)tissue developmentsite-specific developmentchild developmentearly childhood developmentdevelopmental biologyprogressive maturationimmunologyhuman tissuescell biologydevelopmental immunologycognitive developmentearly childhood

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Masaru Kubota

Assistant Professor at the Columbia University Medical Center

Columbia University

Affiliations

Columbia University

P&S

P&S Clinical

SRG Liver

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Masaru Kubota

Columbia University

Assistant Professor at the Columbia University Medical Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Asynchronous Aging and Turnover of Human Circulating and Tissue-Resident Memory T Cells Across Sites. Immunity (2025)

immunity (medicine)adaptive immune systemaging cellimmunologyimmune responsesimmunological memory

Transcriptional Control of T Cell Tissue Adaptation and Effector Function in Infants and Adults. bioRxiv (Cold Spring Harbor Laboratory) (2025)

cellular immune responsesgene expressionadaptive immune systemtranscription factorscell researchimmunologyimmune responsesdevelopmental immunology

Dynamic Establishment and Maintenance of the Human Intestinal B Cell Population and Repertoire Following Transplantation in a Pediatric-Dominated Cohort. Frontiers in Immunology (2024)

organ transplantationpediatricscell transplantationdevelopmental biologyimmunologypediatric-dominated cohortdevelopmental immunologyregenerative medicinedynamic establishment

Human γδ T Cells in Diverse Tissues Exhibit Site-Specific Maturation Dynamics Across the Life Span. Science Immunology (2024)

experimental gerontologyhuman geneticsadaptive immune systemhealth scienceslife spandiverse tissueshuman biologyimmunologydermatologyimmune responsessite-specific maturation dynamics

Maintenance and Functional Regulation of Immune Memory to Covid-19 Vaccines in Tissues. Immunity (2024)

immunity (medicine)vaccinescovid-19immune memoryimmunologyfunctional regulationimmune responsesvaccinationimmunological memory

Multimodal Profiling Reveals Tissue-Directed Signatures of Human Immune Cells Altered With Age. bioRxiv (Cold Spring Harbor Laboratory) (2024)

cell biologyhuman immune cellsimmunologyageing

Dynamic Establishment and Maintenance of the Human Intestinal B Cell Population and Repertoire Following Transplantation. medRxiv (2023)

health sciencesmedicinecell transplantationimmunologyregenerative medicinedynamic establishment

Site-Specific Development and Progressive Maturation of Human Tissue-Resident Memory T Cells Over Infancy and Childhood. Immunity (2023)

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