Faculty

Institution

Unit

Venue

Mary A Schuler

Professor of Cell & Developmental Biology Professor of Biochemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

Department of Cell and Developmental Biology

School of Integrative Biology

School of Molecular & Cellular Biology

Department of Biochemistry

Department of Cell & Developmental Biology

Mary A Schuler is currently serving as a College Of Liberal Arts & Sciences Professor of Cell & Developmental Biology Professor of Biochemistry at Uiuc.

Honors

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Experiences

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Education

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Mary A Schuler

UIUC

Professor of Cell & Developmental Biology Professor of Biochemistry

You can click a keyword to filter the displayed items

biology genetics biochemistry molecular biology molecular genetics insect biochemistry drug metabolism gene expression insect molecular biology plant molecular biology genomics molecular metabolism molecular and cellular biology plant biochemistry genome biology toxins plant biotechnology plant cells chemical biology entomology toxicology plant physiology plant genomics biological chemistry molecular plant pathology plant science pesticide resistance nucleic acids insecticides insect science cell metabolism integrative plant biology biochemical genetics cytochrome p450 monooxygenases plant genetics biochemical sciences plant toxins rna processing gene structure phytochemistry plant biology splice site plant metabolism splicing variant experimental toxicology cytochrome p450 splice site selection furanocoumarin metabolism plant defense gene plant-insect interactions secondary metabolites toxicological mechanism natural product biosynthesis helicoverpa zea carbonyl metabolism gene regulation gene function transcription regulation cellular enzymology papilio polyxenes comparative genomics molecular adaptation gene evolution biochemical taxonomy rna biology cytochrome p450 genes genome sequencing plant hormones il 61801 p450 reductase angular furanocoumarins gene duplication black swallowtail cytochrome p450s active site actin genes gene sequence annotation functional genomics omics datasets systems biology drug discovery

Notable Scholarly Works

Notable Federal Grants

Collaborators

Catalytic Site Constraints in the P450S Mediating Loganic Acid (7Dlh) and Secologanic Acid Synthesis (Slas) in Camptotheca. Biochemistry (2023)

Priya RaoMark A. YaroslavskyJustin C. MillerMary A. Schuler

pharmacognosynatural product biosynthesisnatural productstight specificitypharmacologybiosynthesisterpene indole alkaloidsenzymeschemical biologyorganic synthesisnatural product researchbiocatalysisbiochemistrymedicinal chemistrybiological chemistryphytochemistrybiochemical sciencesnatural product synthesisenzyme inhibitioncatalytic site constraints

Data From Mitochondrial Dna Repair Through Ogg1 Activity Attenuates Breast Cancer Progression and Metastasis. (2023)

Larysa V. YuzefovychAndrea G. KahnMichele A. SchulerLars EideRitu AroraGlenn L. WilsonMing TanLyudmila I. Rachek

metastasisradiation oncologytumor biologycancer biologycell biologymitochondrial dna repaircell metabolismcancer geneticsmitochondrial functioncancer cellsdna repairbreast cancermitochondrial dna

Engineering C–C Bond Cleavage Activity Into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society (2023)

Justin C. MillerJoel H. Z. LeeMark A. McleanRebecca R. ChaoIsobella S. J. StoneTara L. PukalaJohn B. BruningJames J. De VossMary A. SchulerStephen G. SligarStephen G. Bell

metabolic engineeringprocess biochemistryenzymesmolecular metabolismhuman p450 cyp17a1p450 monooxygenase enzymebiocatalysisbiochemistryalcohol dehydrogenasesbiochemical sciencesmolecular biologycarbonyl metabolismcytochrome p450biomolecular engineeringbiosynthesis

Single Mutations Toggle the Substrate Selectivity of Multifunctional Camptotheca Secologanic Acid Synthases. Journal of Biological Chemistry (2022)

Justin C. MillerMary A. Schuler

pharmacognosynatural product researchnatural product biosynthesiscommon slsenzymesnatural productsplant biochemistryphytochemistrysls activitysecondary metabolitesbiochemistrychemical biologynatural product synthesisbiological chemistrypredicted slsdrug discoverybiomolecular engineeringbiosynthesis

P450 Variations Bifurcate the Early Terpene Indole Alkaloid Pathway in Catharanthus Roseus and Camptotheca Acuminata. Phytochemistry (2021)

Justin C. MillerAllison J. HollatzMary A. Schuler

natural product researchcamptotheca acuminataphytochemistrynatural productsplant biochemistryp450 variationscatharanthus roseussecondary metabolitesbiochemistrybiologypharmacologydrug metabolismphytochemical analysisbiosynthesis

Nanodiscs as a New Tool to Examine Lipid–Protein Interactions. Methods in molecular biology (2019)

Ilia G. DenisovMary A. SchulerStephen G. Sligar

biophysicslipidsnanodiscexamine lipid–protein interactionsbiomolecules

Substrate‐Specificity of Cytochrome P450‐Mediated Detoxification as an Evolutionary Strategy for Specialization on Furanocoumarin‐Containing Hostplants: Cyp6ae89 in Parsnip Webworms. Insect Molecular Biology (2019)

B. CallaW.‐Y. WuC. A. E. DeanM. A. SchulerM. R. Berenbaum

molecular and cellular biologyinsect molecular biologyinsect biochemistrycytochrome p450stoxinsbiologybiochemical taxonomyparasite genomicsspecialized cytochrome p450molecular biologybiological chemistrydrug metabolismmolecular evolutioncytochrome p450‐mediated detoxificationgenetics

Allele-Defined Genome of the Autopolyploid Sugarcane Saccharum Spontaneum L.. Nature Genetics (2018)

Jisen ZhangXingtan ZhangHaibao TangQing ZhangXiuting HuaXiaokai MaFan ZhuTyler JonesXinguang ZhuJohn BowersChing Man WaiChunfang ZhengYan ShiShuai ChenXiuming XuJingjing YueDavid R. NelsonLixian HuangZhen LiHuimin XuDong ZhouYongjun WangWeichang HuJishan LinYoujin DengNeha PandeyMelina ManciniDessireé ZerpaJulie K. NguyenLiming WangLiang YuYinghui XinLiangfa GeJie ArroJennifer O. HanSetu ChakrabartyMarija PushkoWenping ZhangYanhong MaPanpan MaMingju LvFaming ChenGuangyong ZhengJingsheng XuZhenhui YangFang DengXuequn ChenZhenyang LiaoXunxiao ZhangZhicong LinHai LinHansong YanZheng KuangWeimin ZhongPingping LiangGuofeng WangYuan YuanJiaxian ShiJinxiang HouJingxian LinJingjing JinPeijian CaoQiaochu ShenQing JiangPing ZhouYaying MaXiaodan ZhangRongrong XuJuan LiuYongmei ZhouHaifeng JiaQing MaRui QiZhiliang ZhangJingping FangHongkun FangJinjin SongMengjuan WangGuangrui DongGang WangZheng ChenTeng MaHong LiuSingha R. DhunganaSarah E. HussXiping YangAnupma SharmaJhon H. TrujilloMaria C. MartinezMatthew HudsonJohn J. RiascosMary SchulerLi-Qing ChenDavid M. BraunLei LiQingyi YuJianping WangKai WangMichael C. SchatzDavid Heckerman

sugarcane chromosomegenome sequencingallele-defined genomegenomicsgenome biologymolecular ecologycomparative genomicsbiologymolecular geneticsevolutionary biologygeneticsmolecular evolutiondisease resistancegenetic variation

Loganic Acid Methyltransferase: Insights Into the Specificity of Methylation on an Iridoid Glycoside. ChemBioChem (2018)

Nektaria PetronikolouAllison J. HollatzMary A. SchulerSatish K. Nair

pharmacognosyindole alkaloidsnatural product researchnatural product biosynthesisnatural productsglycosylationiridoid glycosidesecondary metabolitesbiochemistrymedicinal chemistrybioorganic chemistryloganic acid methyltransferasebioactive compoundsnatural product synthesispharmacologybiotransformationenzyme inhibitionbiosynthesis

Pastinaca Sativa P450S - Cyp71Aj4 Variants in New Zealand and North America. (2018)

Anne CureBernarda CallaMay BerenbaumMary Schuler

new zealandpharmacologymolecular pharmacologydrug discoverypastinaca sativa p450scyp71aj4 variants

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Mary A Schuler

Professor of Cell & Developmental Biology Professor of Biochemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

Department of Cell and Developmental Biology

School of Integrative Biology

School of Molecular & Cellular Biology

Department of Biochemistry

Department of Cell & Developmental Biology

Mary A Schuler is currently serving as a College Of Liberal Arts & Sciences Professor of Cell & Developmental Biology Professor of Biochemistry at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mary A Schuler

UIUC

Professor of Cell & Developmental Biology Professor of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Catalytic Site Constraints in the P450S Mediating Loganic Acid (7Dlh) and Secologanic Acid Synthesis (Slas) in Camptotheca. Biochemistry (2023)

Priya RaoMark A. YaroslavskyJustin C. MillerMary A. Schuler

Data From Mitochondrial Dna Repair Through Ogg1 Activity Attenuates Breast Cancer Progression and Metastasis. (2023)

Larysa V. YuzefovychAndrea G. KahnMichele A. SchulerLars EideRitu AroraGlenn L. WilsonMing TanLyudmila I. Rachek

metastasisradiation oncologytumor biologycancer biologycell biologymitochondrial dna repaircell metabolismcancer geneticsmitochondrial functioncancer cellsdna repairbreast cancermitochondrial dna

Engineering C–C Bond Cleavage Activity Into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society (2023)

Justin C. MillerJoel H. Z. LeeMark A. McleanRebecca R. ChaoIsobella S. J. StoneTara L. PukalaJohn B. BruningJames J. De VossMary A. SchulerStephen G. SligarStephen G. Bell

Single Mutations Toggle the Substrate Selectivity of Multifunctional Camptotheca Secologanic Acid Synthases. Journal of Biological Chemistry (2022)

Justin C. MillerMary A. Schuler

P450 Variations Bifurcate the Early Terpene Indole Alkaloid Pathway in Catharanthus Roseus and Camptotheca Acuminata. Phytochemistry (2021)

Justin C. MillerAllison J. HollatzMary A. Schuler

Nanodiscs as a New Tool to Examine Lipid–Protein Interactions. Methods in molecular biology (2019)

Ilia G. DenisovMary A. SchulerStephen G. Sligar

biophysicslipidsnanodiscexamine lipid–protein interactionsbiomolecules

B. CallaW.‐Y. WuC. A. E. DeanM. A. SchulerM. R. Berenbaum

Allele-Defined Genome of the Autopolyploid Sugarcane Saccharum Spontaneum L.. Nature Genetics (2018)

Loganic Acid Methyltransferase: Insights Into the Specificity of Methylation on an Iridoid Glycoside. ChemBioChem (2018)

Nektaria PetronikolouAllison J. HollatzMary A. SchulerSatish K. Nair

Pastinaca Sativa P450S - Cyp71Aj4 Variants in New Zealand and North America. (2018)

Anne CureBernarda CallaMay BerenbaumMary Schuler

new zealandpharmacologymolecular pharmacologydrug discoverypastinaca sativa p450scyp71aj4 variants

1
2
3
4
5
18
10 / page