Mark S. Chambers

Mark S. Chambers is a Senior Professor at The University of Texas MD Anderson Cancer Center, specializing in oncology, radiation oncology, and oral medicine. His research focuses on osteoradionecrosis of the jaw, head and neck cancer survivorship, and quality-of-life outcomes, with recent work developing clinical and dosimetric datasets, digital decision-support tools, and CT radiomics-based detection methods. He led an international Delphi study establishing consensus criteria for osteoradionecrosis and contributed to a phase 3 trial comparing proton versus photon radiotherapy for oropharyngeal cancer. His publications appear in The Lancet, International Journal of Radiation Oncology*Biology*Physics, and Radiotherapy and Oncology, reflecting his interdisciplinary collaborations across surgery, radiology, and epidemiology.