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Mark Levandoski

Grinnell College

Affiliations

Division of Science

Chemistry

Grinnell College

NoneMark Levandoski is currently serving as a Chemistry faculty at Grinnell College.

Honors

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Experiences

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Mark Levandoski

Grinnell College

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receptors neuroscience neuropsychopharmacology pharmacology neurons neuropharmacology neurotransmitters neurotransmission molecular physiology receptor (biochemistry) neurophysiology allosteric modulation molecular neuroscience pharmacological research nicotine molecular pharmacology neurochemistry biochemistry physiology addiction biology neuropeptide receptors parasitology neural circuits insect science cellular physiology biophysical review experimental pharmacology molecular neurobiology mechanisms of action biochemical interaction computational biophysics experimental biophysics biophysical modeling g protein-coupled receptor noncanonical subunit interfaces anthelmintic levamisole allosteric modulator single-channel properties acetylcholine receptor ascaris suum specificity determinants fine line subunit interfaces molecular dynamics bps2026 - comparison nicotinic receptors β2 c loop structural determinants allosteric modulator specificity

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Comparison of Distinct Allosteric Modulator Sites of Nicotinic Receptors by Molecular Dynamics. Biophysical Journal (2026)

biophysicsreceptorsmolecular dynamicsreceptor (biochemistry)bps2026 – comparisonpharmacological researchbiochemical interactionmechanisms of actionmolecular biophysicsbiochemistrypharmacologynicotinic receptorsmolecular pharmacologybiophysical chemistrymolecular physiology

Structural Determinants of Oxantel Analogs Reveal Modulatory Selectivity of α3β2 and α4β2 Neuronal Nicotinic Acetylcholine Receptors. ACS Omega (2025)

receptorsneuropeptide receptorsstructural determinantsneuropharmacologyneuronsmolecular neuroscienceneuroscienceneurotransmitterspharmacologyneurotransmissionneuropsychopharmacologyaddiction biology

Molecular Dynamics Simulations of Neuronal Nicotinic Acetylcholine Receptor Allosteric Modulation. Biophysical Journal (2024)

biophysicsreceptorsreceptor (biochemistry)biophysical modelingneuronsexperimental biophysicsneurosciencemolecular biophysicscomputational biophysicsmolecular modellingbiophysical chemistrybiophysical review

Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. (2016)

receptorsneurochemistrynicotineneuropharmacologyneuronspharmacological researchallosteric modulationneurosciencepharmacologyneuropsychopharmacology

The β2 Subunit C Loop of the Nicotinic Acetylcholine Receptor Directs Allosteric Modulator Specificity. Biochemical Pharmacology (2015)

receptorsreceptor (biochemistry)nicotinepharmacological researchneuroscienceg protein-coupled receptornicotinic acetylcholine receptorpharmacologymolecular pharmacologyallosteric modulator specificityneuropsychopharmacologymolecular physiology

Subunit Interfaces Contribute Differently to Activation and Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. Neuropharmacology (2014)

receptorsreceptor (biochemistry)neuronsallosteric modulationneuroscienceneurotransmitterssubunit interfacesbiochemistryneurotransmissionneuropsychopharmacologymolecular physiology

Does the β2 C Loop of the Neuronal Nicotinic Acetylcholine Receptor Dictate the Type of Allosteric Modulation?. Biochemical Pharmacology (2013)

receptorsreceptor (biochemistry)neuropharmacologyneuronsallosteric modulationneurosciencepharmacologyneurotransmissionβ2 c loopneurophysiologyneuropsychopharmacologyaddiction biology

Intra-Subunit Flexibility Underlies Activation and Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. Neuropharmacology (2013)

receptorsnicotineneuropharmacologymolecular neuroscienceneuronsallosteric modulationneuroscienceneurotransmitterspharmacologyneurotransmissionneurophysiologyneuropsychopharmacologymolecular physiology

Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors Requires Inter-Subunit Movement. Biochemical Pharmacology (2011)

receptorsreceptor (biochemistry)neuropharmacologyneuronsallosteric modulationneuroscienceneurotransmitterspharmacologyneurotransmissionneurophysiologyneuropsychopharmacologymolecular physiology

Specificity Determinants of Allosteric Modulation in the Neuronal Nicotinic Acetylcholine Receptor: A Fine Line Between Inhibition and Potentiation. Molecular Pharmacology (2011)

receptorsallosteric modulationneurosciencepharmacologymolecular pharmacologyneuropsychopharmacologyneurophysiologyneuropharmacologymolecular neurosciencephysiologyneurotransmissionneural circuitsneurochemistrynicotinepharmacological researchneuronsneurotransmittersfine linespecificity determinants

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Mark Levandoski

Grinnell College

Affiliations

Division of Science

Chemistry

Grinnell College

NoneMark Levandoski is currently serving as a Chemistry faculty at Grinnell College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mark Levandoski

Grinnell College

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Comparison of Distinct Allosteric Modulator Sites of Nicotinic Receptors by Molecular Dynamics. Biophysical Journal (2026)

Structural Determinants of Oxantel Analogs Reveal Modulatory Selectivity of α3β2 and α4β2 Neuronal Nicotinic Acetylcholine Receptors. ACS Omega (2025)

receptorsneuropeptide receptorsstructural determinantsneuropharmacologyneuronsmolecular neuroscienceneuroscienceneurotransmitterspharmacologyneurotransmissionneuropsychopharmacologyaddiction biology

Molecular Dynamics Simulations of Neuronal Nicotinic Acetylcholine Receptor Allosteric Modulation. Biophysical Journal (2024)

Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. (2016)

receptorsneurochemistrynicotineneuropharmacologyneuronspharmacological researchallosteric modulationneurosciencepharmacologyneuropsychopharmacology

The β2 Subunit C Loop of the Nicotinic Acetylcholine Receptor Directs Allosteric Modulator Specificity. Biochemical Pharmacology (2015)

Subunit Interfaces Contribute Differently to Activation and Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. Neuropharmacology (2014)

receptorsreceptor (biochemistry)neuronsallosteric modulationneuroscienceneurotransmitterssubunit interfacesbiochemistryneurotransmissionneuropsychopharmacologymolecular physiology

Does the β2 C Loop of the Neuronal Nicotinic Acetylcholine Receptor Dictate the Type of Allosteric Modulation?. Biochemical Pharmacology (2013)

receptorsreceptor (biochemistry)neuropharmacologyneuronsallosteric modulationneurosciencepharmacologyneurotransmissionβ2 c loopneurophysiologyneuropsychopharmacologyaddiction biology

Intra-Subunit Flexibility Underlies Activation and Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors. Neuropharmacology (2013)

Allosteric Modulation of Neuronal Nicotinic Acetylcholine Receptors Requires Inter-Subunit Movement. Biochemical Pharmacology (2011)

receptorsreceptor (biochemistry)neuropharmacologyneuronsallosteric modulationneuroscienceneurotransmitterspharmacologyneurotransmissionneurophysiologyneuropsychopharmacologymolecular physiology

Specificity Determinants of Allosteric Modulation in the Neuronal Nicotinic Acetylcholine Receptor: A Fine Line Between Inhibition and Potentiation. Molecular Pharmacology (2011)

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2
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