Faculty

Institution

Unit

Venue

Marie Egan

Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology

Yale University

Affiliations

Cellular & Molecular Physiology

Marie Egan is currently serving as a Cellular & Molecular Physiology Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology at Yale University.

Honors

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Experiences

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Education

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Marie Egan

Yale University

Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology

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cystic fibrosis immunology respiratory medicine pharmacology inflammation membrane biology cellular physiology fibrosis physiology medicinal research genetics veterinary medicine mammalian biology membrane transport molecular physiology gene expression nanomedicine pediatric pulmonology clinical microbiology cell physiology liver physiology nanotechnology nanoparticle research protein science infection control nanobiotechnology pharmaceutical nanotechnology protein transport nanomaterials redox biology mammalian physiology clinical immunology knockout mice animal physiology applied physiology biological chemistry vascular biology cellular biology therapeutic nanomaterials molecular neurobiology cell trafficking molecular regulation host factors gene editing paediatric medicine renal function release mechanism biochemical genetics heme homeostasis heme signaling nutrient physiology experimental pharmacology clinical infection cystic fibrosis defects chloride channel myosin ia ion transport cftr-mediated chloride transport physiological research human physiology microbial disease medical microbiology translational pharmacology pharmacokinetics viral evolution rectifying chloride channels autocrine mechanism global chemical effects major constituent conductance regulator defective regulation chronic colonization functional surface expression calcium-pump inhibitors site-specific fashion recombinant adeno-associated virus

Notable Scholarly Works

Notable Federal Grants

Collaborators

Effects of Elexacaftor/Tezacaftor/Ivacaftor on Cough Frequency, Physical Activity Patterns, and Sleep Quality in Adolescents and Adults With Cystic Fibrosis. Journal of Cystic Fibrosis (2026)

chronic obstructive pulmonary diseasemedicinesleep disordersphysical activity patternssleepsleep medicinecystic fibrosispulmonary carecough frequencyrespiratory medicinehealth sciences

182 Eti Treatment Modulates Ifn Signaling in Airway Immune Cells From Children With Cystic Fibrosis. Journal of Cystic Fibrosis (2025)

immune responsespediatric pulmonologyairway immune cellscystic fibrosisimmunologyrespiratory medicineinfectious respiratory diseaseimmunopathologyallergy

194 Restoration of Ezrin via Calpain Inhibition Reinstates Immune Function in Cystic Fibrosis Alveolar Macrophages. Journal of Cystic Fibrosis (2025)

immune responsespulmonary pharmacologyfibrosisinflammationcell biologycell signalingmedicinal researchcystic fibrosiscalpain inhibitionimmunologypharmacologyimmune functionsignal transductionmolecular medicinecellular physiology

197 Reduced Levels of Active Hepatocyte Growth Factor Correlate With Lung Damage in a Cf Mouse Model. Journal of Cystic Fibrosis (2025)

hepatologycf mouse modelreduced levelsliver physiologyfibrosisinflammationcell biologycystic fibrosisinterstitial lung diseasefibroblast growth factorsrespiratory medicineliver diseasecell deathmolecular medicinelung damagepathology

244 Restoration of in Vivo Cftr Function by Tracheal Basal Cell Engraftment. Journal of Cystic Fibrosis (2025)

developmental biologystem cell researchvivo cftr functionsoft tissue reconstructioncell biologycystic fibrosisregenerative medicinebiomedical engineeringtracheobronchitiscellular physiology

253 an Electrochemiluminescence Immunoassay to Quantify Cftr Protein Across Species. Journal of Cystic Fibrosis (2025)

immunochemistryanalytical biotechnologyprotein sciencemembrane proteinsbiochemistryproteomicsprotein expressioncftr proteinmolecular biologybiomedical analysisclinical proteomicsbioanalysisbiomarkers

362 Dramatic Shifts in Resident Immune Cell Populations Accompany Cf Mouse Ileum Remodeling During Development. Journal of Cystic Fibrosis (2025)

developmental biologyimmune responsesdigestive diseasesinflammationdramatic shiftsgut barriermicrobiomecell biologyimmunologyimmunity (medicine)cf mouse ileumgut microbesmucosal immunologydevelopmental immunology

365 Chronic Lung Inflammation in Cystic Fibrosis Drives Maladaptive Trained Tmmunity in Hematopoietic Stem Cells. Journal of Cystic Fibrosis (2025)

chronic obstructive pulmonary diseasestem cell researchimmune responsesfibrosisinflammationchronic lung inflammationstem cellscell biologycystic fibrosisimmunologytrained tmmunityrespiratory medicinecystic fibrosis drivespulmonary diseasespathology

Chronic Pulmonary Lps Exposure in Cystic Fibrosis Drives Maladaptive Pro-Inflammatory Hematopoietic Stem and Progenitor Cells. Blood (2025)

chronic obstructive pulmonary diseaseimmune responsesfibrosisprogenitor cellsinflammationcell biologycystic fibrosisimmunologyautoimmunityrespiratory medicinepulmonary diseasespathology

Increased Prevalence of Autoantibodies Neutralizing Ifnλ2/3 in Young Individuals With Cystic Fibrosis. Journal of Human Immunity (2025)

inborn errors of immunityimmune responsesautoimmune diseasesautoantibody productiondisease susceptibilityfibrosisimmunologic diseasesyoung individualscystic fibrosisimmunologyimmunity (medicine)autoimmunityrheumatismpediatric allergypathology

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Marie Egan

Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology

Yale University

Affiliations

Cellular & Molecular Physiology

Marie Egan is currently serving as a Cellular & Molecular Physiology Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Marie Egan

Yale University

Professor of Pediatrics Respiratory and of Cellular And Molecular Physiology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Effects of Elexacaftor/Tezacaftor/Ivacaftor on Cough Frequency, Physical Activity Patterns, and Sleep Quality in Adolescents and Adults With Cystic Fibrosis. Journal of Cystic Fibrosis (2026)

chronic obstructive pulmonary diseasemedicinesleep disordersphysical activity patternssleepsleep medicinecystic fibrosispulmonary carecough frequencyrespiratory medicinehealth sciences

182 Eti Treatment Modulates Ifn Signaling in Airway Immune Cells From Children With Cystic Fibrosis. Journal of Cystic Fibrosis (2025)

immune responsespediatric pulmonologyairway immune cellscystic fibrosisimmunologyrespiratory medicineinfectious respiratory diseaseimmunopathologyallergy

194 Restoration of Ezrin via Calpain Inhibition Reinstates Immune Function in Cystic Fibrosis Alveolar Macrophages. Journal of Cystic Fibrosis (2025)

197 Reduced Levels of Active Hepatocyte Growth Factor Correlate With Lung Damage in a Cf Mouse Model. Journal of Cystic Fibrosis (2025)

244 Restoration of in Vivo Cftr Function by Tracheal Basal Cell Engraftment. Journal of Cystic Fibrosis (2025)

developmental biologystem cell researchvivo cftr functionsoft tissue reconstructioncell biologycystic fibrosisregenerative medicinebiomedical engineeringtracheobronchitiscellular physiology

253 an Electrochemiluminescence Immunoassay to Quantify Cftr Protein Across Species. Journal of Cystic Fibrosis (2025)

immunochemistryanalytical biotechnologyprotein sciencemembrane proteinsbiochemistryproteomicsprotein expressioncftr proteinmolecular biologybiomedical analysisclinical proteomicsbioanalysisbiomarkers

362 Dramatic Shifts in Resident Immune Cell Populations Accompany Cf Mouse Ileum Remodeling During Development. Journal of Cystic Fibrosis (2025)

365 Chronic Lung Inflammation in Cystic Fibrosis Drives Maladaptive Trained Tmmunity in Hematopoietic Stem Cells. Journal of Cystic Fibrosis (2025)

Chronic Pulmonary Lps Exposure in Cystic Fibrosis Drives Maladaptive Pro-Inflammatory Hematopoietic Stem and Progenitor Cells. Blood (2025)

chronic obstructive pulmonary diseaseimmune responsesfibrosisprogenitor cellsinflammationcell biologycystic fibrosisimmunologyautoimmunityrespiratory medicinepulmonary diseasespathology

Increased Prevalence of Autoantibodies Neutralizing Ifnλ2/3 in Young Individuals With Cystic Fibrosis. Journal of Human Immunity (2025)

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