Mariana Chavez Mac Gregor, M.D., MSC

Mariana Chavez Mac Gregor, M.D., MSC, is a tenured Professor in the Department of Breast Medical Oncology at The University of Texas MD Anderson Cancer Center. Her research focuses on optimizing breast cancer treatment, with specific interests in chemotherapy de-escalation and declination in early-stage hormone receptor-positive disease, real-world adoption of neoadjuvant chemoimmunotherapy in high-risk triple-negative breast cancer, and late effects of chemotherapy on older survivors. Her recent work includes ctDNA and tumor-based biomarkers of giredestrant response in the acelERA trial, published in Nature Communications, and population-based studies of Medicare enrollees in Texas. She is recognized for her contributions to cancer outcomes research and health services.