Marian Kalocsay

Marian Kalocsay is an Assistant Professor at The University of Texas MD Anderson Cancer Center, where his research integrates cell biology, molecular biology, proteomics, and genetics to address fundamental questions in cell signaling and protein science. His recent work employs proximity proteomics and high-throughput platforms to map protein interaction networks, including NANOG neighborhood hubs linked to mesenchymal stem cell stemness and chromatin control. He has also pioneered a human iPSC-derived sensory neuron platform for discovering neuroprotectants against chemotherapy-induced peripheral neuropathy, and his collaborative studies have elucidated TYK2-mediated neuroinflammation in Alzheimer’s disease with TDP-43 pathology, CDK12/7/9 degradation enhancing PARP inhibitor sensitivity in prostate cancer, and structural dynamics of metabotropic glutamate receptor/beta-arrestin coupling. His publications appear in venues such as Nature Communications, Science Advances, and Cell Reports Medicine.