Faculty

Institution

Unit

Venue

Margalit Mokyr

University of Illinois Chicago

Affiliations

College of Medicine

Department of Biochemistry and Molecular Genetics

NoneMargalit Mokyr is currently serving as a College Of Medicine faculty at University of Illinois Chicago.

Honors

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Experiences

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Education

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Margalit Mokyr

University of Illinois Chicago

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immunology oncology cancer immunotherapy medicine pharmacology tumor biology cancer research cancer treatment medicinal research immunotherapy clinical immunology cellular therapy tumor targeting immune responses melanoma cancer biology cell biology anti-cancer agents cytokines cancer care cancer cells pharmacotherapy leukemia medical mycology tumor suppressors cell therapy cell regulation cellular immune responses mammalian biology spleen cells antitumor cytotoxicity gene expression molecular cancer lymphoid neoplasia immunomodulation receptors cell death in vitro toxicology in vivo systems t-regulatory cell hematological malignancies clinical transplantation adaptive immune system lymphocyte development low dose adoptive chemoimmunotherapy enzyme inhibition surgical oncology oncogenes experimental medicine immunotoxicology cancer genetics immunosuppression therapeutic efficacy clinical medicine antitumor immunity low-dose melphalan therapy novel therapies treatment effects apoptosis immunosuppressive therapy cancer management cancer risk host antitumor immunity norepinephrine-mediated inhibition lymphoid cells tumor-eradicating immunity curative effectiveness immunosuppressed spleen cells cancer therapy therapeutic effectiveness low dose melphalan melphalan-induced enhancement mode of action cancer growth treatment options

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4755: Importance of an Induction Dose to the Immunogenicity of Cancer Vaccines: A Reverse Translational Study. Cancer Research (2010)

David A. BerdDonald BraunMargalit B. Mokyr

vaccinationmedicineoncologycancer researchcancer biologyimmunologyreverse translational studyinduction dosehealth sciences

The Xeroderma Pigmentosum Group E Gene Product Ddb2 Activates Nucleotide Excision Repair by Regulating the Level of P21 Waf1/Cip1. Molecular and Cellular Biology (2007)

Tanya StoyanovaTaewon YoonDragana KopanjaMargalit B. MokyrPradip Raychaudhuri

geneticsgene expressionmolecular and cellular biologycell regulationnucleotide excision repairgene regulationcell biologycell signalingmolecular regulationcell and molecular biologysignal transductiongene functionmolecular biologytranscription regulationxeroderma pigmentosum group

Importance of Signaling via the Ifn-α/β Receptor on Host Cells for the Realization of the Therapeutic Benefits of Cyclophosphamide for Mice Bearing a Large Mopc-315 Tumor. Cancer Immunology Immunotherapy (2005)

Margalit B. MokyrAaron T. PlaceJames E. ArtwohlVE Ted Valli

receptorscancer immunotherapysignaling pathwaysmedicineanti-cancer agentsoncologyhost cellscell signalingtherapeutic benefitsimmunotherapyimmunologypharmacologycancer treatmenttumor targetingcytokinesmedicinal research

Importance of Il-10 for Ctla-4-Mediated Inhibition of Tumor-Eradicating Immunity. The Journal of Immunology (2004)

Vladimir M. JovasevicLeonid GorelikJeffrey A. BluestoneMargalit B. Mokyr

immune responsesadaptive immune systemclinical immunologyimmunologycytokinestumor-eradicating immunity

Melphalan-Induced Up-Regulation of B7–1 Surface Expression on Normal Splenic B Cells. Cancer Immunology Immunotherapy (2003)

Manjula DonepudiVladimir M. JovasevicPradip RaychaudhuriMargalit B. Mokyr

cancer immunotherapymelphalan-induced up-regulationcell regulationcell biologycell signalingimmunotherapyimmunologypharmacology

Mechanism of Melphalan-Induced B7-1 Gene Expression in P815 Tumor Cells. The Journal of Immunology (2001)

Manjula DonepudiPradip RaychaudhuriJeffrey A. BluestoneMargalit B. Mokyr

tumor biologygeneticsmelanomacancer researchcancer biologycell biologycancer cellsimmunologygene expressioncancer genetics

Melphalan-Induced Expression of Ifn-β in Mopc-315 Tumor-Bearing Mice and Its Importance for the Up-Regulation of Tnf-α Expression. The Journal of Immunology (2001)

Vladimir M. JovasevicMargalit B. Mokyr

tumor biologygeneticsimmune responsesmelanomaoncologycell regulationmelphalan-induced expressionmolecular immunologyclinical immunologyimmunologypharmacologymammalian biologytnf-a expressiongene expressioncancer geneticsmedicinal research

Melphalan and Other Anticancer Modalities Up-Regulate B7-1 Gene Expression in Tumor Cells. The Journal of Immunology (2000)

Dorothy K. SojkaManjula DonepudiJeffrey A. BluestoneMargalit B. Mokyr

cancer immunotherapyanti-cancer agentsmelanomaoncologycancer researchcell regulationcancer biologycell biologyimmunologypharmacologycytokinesgene expressiontumor cells

Host B7-1 and B7-2 Costimulatory Molecules Contribute to the Eradication of B7-1-Transfected P815 Tumor Cells via a Cd8+ T Cell-Dependent Mechanism. The Journal of Immunology (1999)

Ross N. La MotteArlene H. SharpeJeffrey A. BluestoneMargalit B. Mokyr

vaccinationtumor biologyimmune responsescellular therapyapoptosisoncologycancer researcht-regulatory cellcell regulationdermatologycell biologycancer cellsadaptive immune systemclinical immunologyimmunology

Norepinephrine-Mediated Inhibition of Antitumor Cytotoxic T Lymphocyte Generation Involves a Beta-Adrenergic Receptor Mechanism and Decreased Tnf-Alpha Gene Expression.. PubMed (1999)

V V KalinichenkoM B MokyrL H GrafR L CohenD A Chambers

tumor biologyimmune responsescancer immunotherapynovel therapiescell biologyoncogenesimmunologypharmacologynorepinephrine-mediated inhibitiontnf-alpha gene expressionbeta-adrenergic receptor mechanismcytokinesgene expressiontumor microenvironmentcellular immune responses

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Margalit Mokyr

University of Illinois Chicago

Affiliations

College of Medicine

Department of Biochemistry and Molecular Genetics

NoneMargalit Mokyr is currently serving as a College Of Medicine faculty at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Margalit Mokyr

University of Illinois Chicago

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4755: Importance of an Induction Dose to the Immunogenicity of Cancer Vaccines: A Reverse Translational Study. Cancer Research (2010)

David A. BerdDonald BraunMargalit B. Mokyr

vaccinationmedicineoncologycancer researchcancer biologyimmunologyreverse translational studyinduction dosehealth sciences

The Xeroderma Pigmentosum Group E Gene Product Ddb2 Activates Nucleotide Excision Repair by Regulating the Level of P21 Waf1/Cip1. Molecular and Cellular Biology (2007)

Tanya StoyanovaTaewon YoonDragana KopanjaMargalit B. MokyrPradip Raychaudhuri

Margalit B. MokyrAaron T. PlaceJames E. ArtwohlVE Ted Valli

Importance of Il-10 for Ctla-4-Mediated Inhibition of Tumor-Eradicating Immunity. The Journal of Immunology (2004)

Vladimir M. JovasevicLeonid GorelikJeffrey A. BluestoneMargalit B. Mokyr

immune responsesadaptive immune systemclinical immunologyimmunologycytokinestumor-eradicating immunity

Melphalan-Induced Up-Regulation of B7–1 Surface Expression on Normal Splenic B Cells. Cancer Immunology Immunotherapy (2003)

Manjula DonepudiVladimir M. JovasevicPradip RaychaudhuriMargalit B. Mokyr

cancer immunotherapymelphalan-induced up-regulationcell regulationcell biologycell signalingimmunotherapyimmunologypharmacology

Mechanism of Melphalan-Induced B7-1 Gene Expression in P815 Tumor Cells. The Journal of Immunology (2001)

Manjula DonepudiPradip RaychaudhuriJeffrey A. BluestoneMargalit B. Mokyr

tumor biologygeneticsmelanomacancer researchcancer biologycell biologycancer cellsimmunologygene expressioncancer genetics

Melphalan-Induced Expression of Ifn-β in Mopc-315 Tumor-Bearing Mice and Its Importance for the Up-Regulation of Tnf-α Expression. The Journal of Immunology (2001)

Vladimir M. JovasevicMargalit B. Mokyr

Melphalan and Other Anticancer Modalities Up-Regulate B7-1 Gene Expression in Tumor Cells. The Journal of Immunology (2000)

Dorothy K. SojkaManjula DonepudiJeffrey A. BluestoneMargalit B. Mokyr

cancer immunotherapyanti-cancer agentsmelanomaoncologycancer researchcell regulationcancer biologycell biologyimmunologypharmacologycytokinesgene expressiontumor cells

Host B7-1 and B7-2 Costimulatory Molecules Contribute to the Eradication of B7-1-Transfected P815 Tumor Cells via a Cd8+ T Cell-Dependent Mechanism. The Journal of Immunology (1999)

Ross N. La MotteArlene H. SharpeJeffrey A. BluestoneMargalit B. Mokyr

Norepinephrine-Mediated Inhibition of Antitumor Cytotoxic T Lymphocyte Generation Involves a Beta-Adrenergic Receptor Mechanism and Decreased Tnf-Alpha Gene Expression.. PubMed (1999)

V V KalinichenkoM B MokyrL H GrafR L CohenD A Chambers

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brain tumor research

oncology

Robert Baiocchi

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Ohio State University

evolutionary data mining

optimization-based data mining

Zihai Li

Institution

Ohio State University

biomedical informatics

systems biology

Herbert Kim Lyerly

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oncology

cancer research

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proteomics

chemical cleavage mechanisms

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