Faculty

Institution

Unit

Venue

C. Marcelo Aldaz, M.D., Ph.D.

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

C. Marcelo Aldaz, M.d., Ph.d. is currently serving as an Epigenetics And Molecular Carcinogenesis Professor at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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C. Marcelo Aldaz, M.D., Ph.D.

The University of Texas MD Anderson Cancer Center

Professor

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tumor biology cancer research genetics molecular biology carcinogenesis cancer genetics cell biology pathology cancer biology cancer cells breast cancer oncogenes oncology molecular cancer gene expression cutaneous biology molecular cell biology mammalian biology breast oncology cytogenetics skin cancer genome biology cancer genomics tumor suppressors transcription factors medicinal research chromosome biology dna repair cancer discovery cancer imaging protein science gynecologic oncology skin development molecular diagnostics histopathology signaling pathways mammary gland knockout mice anti-cancer agents experimental dermatology proteome research cancer letter gene regulation liver cancer malignant disease sencar mice stem cell research gene function biomolecular interactions oncogenic agent cancer growth endocrine-related cancers hormonal receptor dermatopathology photocarcinogenesis breast cancer cells mouse skin tumors epigenetic changes genome instability gene characterization oral cancer genitourinary cancers chromosomal rearrangements situ hybridization fra16d gene high frequency serial analysis mutated ha-ras-1 allele nonrandom duplication mouse mammary tumors wwox protein expression wwox deletion paraffin-embedded tissue sections wwox protein interactome genomic instability cigarette smoke

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endogenous Processes Underlying Clock‐Like Mutational Signatures. Genes Chromosomes and Cancer (2026)

mutagenesis (molecular biology technique)theoretical biologyevolutionary dynamicsendogenous processesmutation-based testinggeneticsdynamical systems

B-Cell–Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Proinflammatory Signatures in Myeloma Model. Blood Neoplasia (2025)

oncogenesb-cell–specific wwox deletionpathologymyeloma modeltumor biologycell deathplasmablastic tumor developmentimmunologycell biologyhematological malignanciescancer cellstumor microenvironmentmyeloid neoplasia

Partial Wwox Loss of Function Increases Severity of Murine Sepsis and Neuroinflammation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

inflammationpsychoneuroimmunologypartial wwox lossmurine sepsistranslational medicineimmunologysepsisneuroimmunologyfunction increases severitymedicineclinical researchcritical care

Repurposing of the Macrolide Antibiotic Clarithromycin for the Prevention of Lung Cancer. Molecular Cancer Therapeutics (2025)

antimicrobial agentsinfectious diseasespharmaceuticsantibiotic resistancelung cancermacrolide antibiotic clarithromycinantimicrobial compoundsmedicinepharmacologytherapeutic targetsantibioticsantibacterial agentsdrug discovery

Therapeutic Potential of Prmt1 as a Critical Survival Dependency Target in Multiple Myeloma. BMC Cancer (2025)

radiation oncologytumor biologycell biologyhematological malignanciesmolecular cancertherapeutic potentialcancer researchmultiple myelomatherapeutic targetscancer cellsoncologymyeloid neoplasia

Endothelial Knockdown of the Tumor Suppressor, Wwox, Increases Inflammation in Ventilator-Induced Lung Injury. American Journal of Physiology-Lung Cellular and Molecular Physiology (2024)

Zhenguo ZengEltyeb AbdelwahidWeiguo ChenChristian AscoliTrinh PhamJeffrey R. JacobsonSteven M. DudekViswanathan NatarajanC. Marcelo AldazRoberto F. MachadoSunit Singla

inflammationendothelial knockdownphysiologycellular physiologyventilator-induced lung injurymolecular physiologytumor suppressors

Abstract 17443: Wwox is a Critical Regulator of Pulmonary Artery Smooth Muscle Cell Homeostasis. Circulation (2023)

Marta T GomesJiwang ChenRafael PolidoroYang BaiClare ProhaskaSunit SinglaC. Marcelo M AldazRobert StearmanRoberto F Machado

vascular biologyregenerative medicinecardiologycirculatory physiologyphysiologypulmonary circulationcell biologyrespiratory medicinecritical regulatorhealth sciences

Data From a Molecular Portrait of High-Grade Ductal Carcinoma I in Situ /I. (2023)

Martin C. AbbaTing GongYue LuJaeho LeeYi ZhongEzequiel LacunzaMatias ButtiYoko TakataSally GaddisJianjun ShenMarcos R. EstecioAysegul A. SahinC. Marcelo Aldaz

molecular portraitradiation oncologyliver cancertumor biologycancer biologycancer researchmolecular biologycancer geneticscancer genomicsstructural biologygenetics

Data From Breast Cancer Molecular Signatures as Determined by Sage: Correlation With Lymph Node Status. (2023)

Martín C. AbbaHongxia SunKathleen A. HawkinsJeffrey A. DrakeYuhui HuMaria I. NunezSally GaddisTao ShiSteve HorvathAysegul SahinC. Marcelo Aldaz

immunologylymph node statushematologycancer researchhealth sciencesoncologybreast cancer

Data From From Mice to Humans. (2023)

Yuhui HuHongxia SunJeffrey DrakeFrances KittrellMartin C. AbbaLi DengSally GaddisAysegul SahinKeith BaggerlyDaniel MedinaC. Marcelo Aldaz

biostatisticsbiological datagenomicsdata modelingdata sciencescientific datamammalian biologystatistics

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C. Marcelo Aldaz, M.D., Ph.D.

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

C. Marcelo Aldaz, M.d., Ph.d. is currently serving as an Epigenetics And Molecular Carcinogenesis Professor at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

C. Marcelo Aldaz, M.D., Ph.D.

The University of Texas MD Anderson Cancer Center

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endogenous Processes Underlying Clock‐Like Mutational Signatures. Genes Chromosomes and Cancer (2026)

mutagenesis (molecular biology technique)theoretical biologyevolutionary dynamicsendogenous processesmutation-based testinggeneticsdynamical systems

B-Cell–Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Proinflammatory Signatures in Myeloma Model. Blood Neoplasia (2025)

Partial Wwox Loss of Function Increases Severity of Murine Sepsis and Neuroinflammation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

inflammationpsychoneuroimmunologypartial wwox lossmurine sepsistranslational medicineimmunologysepsisneuroimmunologyfunction increases severitymedicineclinical researchcritical care

Repurposing of the Macrolide Antibiotic Clarithromycin for the Prevention of Lung Cancer. Molecular Cancer Therapeutics (2025)

Therapeutic Potential of Prmt1 as a Critical Survival Dependency Target in Multiple Myeloma. BMC Cancer (2025)

radiation oncologytumor biologycell biologyhematological malignanciesmolecular cancertherapeutic potentialcancer researchmultiple myelomatherapeutic targetscancer cellsoncologymyeloid neoplasia

Endothelial Knockdown of the Tumor Suppressor, Wwox, Increases Inflammation in Ventilator-Induced Lung Injury. American Journal of Physiology-Lung Cellular and Molecular Physiology (2024)

Zhenguo ZengEltyeb AbdelwahidWeiguo ChenChristian AscoliTrinh PhamJeffrey R. JacobsonSteven M. DudekViswanathan NatarajanC. Marcelo AldazRoberto F. MachadoSunit Singla

inflammationendothelial knockdownphysiologycellular physiologyventilator-induced lung injurymolecular physiologytumor suppressors

Abstract 17443: Wwox is a Critical Regulator of Pulmonary Artery Smooth Muscle Cell Homeostasis. Circulation (2023)

Marta T GomesJiwang ChenRafael PolidoroYang BaiClare ProhaskaSunit SinglaC. Marcelo M AldazRobert StearmanRoberto F Machado

vascular biologyregenerative medicinecardiologycirculatory physiologyphysiologypulmonary circulationcell biologyrespiratory medicinecritical regulatorhealth sciences

Data From a Molecular Portrait of High-Grade Ductal Carcinoma I in Situ /I. (2023)

Martin C. AbbaTing GongYue LuJaeho LeeYi ZhongEzequiel LacunzaMatias ButtiYoko TakataSally GaddisJianjun ShenMarcos R. EstecioAysegul A. SahinC. Marcelo Aldaz

molecular portraitradiation oncologyliver cancertumor biologycancer biologycancer researchmolecular biologycancer geneticscancer genomicsstructural biologygenetics

Data From Breast Cancer Molecular Signatures as Determined by Sage: Correlation With Lymph Node Status. (2023)

Martín C. AbbaHongxia SunKathleen A. HawkinsJeffrey A. DrakeYuhui HuMaria I. NunezSally GaddisTao ShiSteve HorvathAysegul SahinC. Marcelo Aldaz

immunologylymph node statushematologycancer researchhealth sciencesoncologybreast cancer

Data From From Mice to Humans. (2023)

Yuhui HuHongxia SunJeffrey DrakeFrances KittrellMartin C. AbbaLi DengSally GaddisAysegul SahinKeith BaggerlyDaniel MedinaC. Marcelo Aldaz

biostatisticsbiological datagenomicsdata modelingdata sciencescientific datamammalian biologystatistics

1
2
3
4
5
18
10 / page