Mamdooh H. Ghoneum

Charles R. Drew University of Medicine and Science

Affiliations

College of Medicine

Department Of General Surgery

Department Of Neuro-Ophthalmology And Ophthalmic Plastic Surgery

NoneMamdooh H. Ghoneum is currently serving as a College Of Medicine faculty at Charles R. Drew University of Medicine And Science.

Honors

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Experiences

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Education

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Mamdooh H. Ghoneum

Charles R. Drew University of Medicine and Science

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pharmacology immunology cell biology bioactive compounds cancer research tumor biology biochemistry phytotherapy research cell death cancer cells medicinal research immune responses molecular cancer cancer letter natural products oxidative stress oncogenes antioxidants medicinal foods cellular therapy in vitro toxicology oncology experimental medicine free radical biology biotechnology functional foods natural product research apoptosis arabinoxylan rice bran pharmacognosy cancer biology breast oncology cancer treatment biomedical research yeast chemoprevention strategies immunopathology nutritional sciences clinical immunology diabetes therapy hydroferrate fluid rice bran anti-cancer agents nanobiotechnology nanoplatinum liquid anti-inflammatory innate immune system cytokines key site hematological malignancies tumor targeting cancer prevention cancer detection gastrointestinal oncology immunomodulation experimental nutrition t-regulatory cell cellular immune responses saccharomyces cerevisiae placebo-controlled clinical trial novel kefir product human dendritic cells immunoglobulin e mucosal immunology cancer risk cancer screening hepatocellular carcinoma functional modification industrial mycology tumor necrosis modified arabinoxylan death receptor hole-piercing mechanism apoptotic effect chemotherapeutic agent interventional therapies

Notable Scholarly Works

Notable Federal Grants

Collaborators

Biobran/Mgn-3, Arabinoxylan Rice Bran, Ameliorates the Liver Architecture in Ehrlich Ascites Tumor-Bearing Mice as a Cotreatment With Chemotherapy. Integrative Cancer Therapies (2026)

oncogenescancer cellstumor biologyliver physiologymolecular medicinecell biologymetabolic pathwaysmolecular cancerbiochemistrycarcinogenesiscancer researchbioactive compoundscancer discoverypharmacologytherapeutic targetsphytotherapy researchcancer letter

Synchronizing Activity of Biobran/Mgn-3 With Exosomes: Therapeutic Targeting of Hypoxia Pathway to Inhibit Angiogenesis and Proliferation of Breast Invasive Ductal Carcinoma. Applied Food Research (2026)

extracellular matrixoncogenesmetastasistumor biologymatrix biologycell biologymedicinal researchmolecular cancerbiochemistrycancer researchcancer discoverypharmacologytherapeutic targetscancer cellscancer lettertumor microenvironmentbreast cancer

Biobran/Mgn-3: A Promising Natural Strategy for Mitigating Kidney Damage and Immune Modulation During Etoposide Therapy. Journal of Bioscience and Applied Research/Journal of Bioscience and Applied Research (2025)

inflammationvascular biologycell deathtranslational medicinemolecular medicinemedicinal researchcell signalingimmunologyfree radical biologycell biologymolecular physiologypharmacologyexperimental medicinemolecular pharmacologytherapeutic targetspharmacological researchreceptors

Chitosan || Biobran/Pva || Chitosan/Pva Tri-Layered Nanofiber Scaffold: A Biphasic Release System With Physicochemical Properties Conducive to Skin Tissue Engineering. Carbohydrate Polymer Technologies and Applications (2025)

controlled releasebiological engineeringcarbohydrate polymerfibre chemistrydrug deliverywound healingnanomedicinepharmaceuticsbiopolymersbiomedical engineeringbiomanufacturingbiomolecular engineeringnanoparticle researchbiomaterialsbiomimetic materialstissue engineeringbiofabrication

Efficacy of Plasmalogens on Monosodium Glutamate‐Induced Neurotoxicity in Male Rats Through Nf‐ κ B and P38 Mapk Signaling Pathways. Oxidative Medicine and Cellular Longevity (2025)

molecular neurosciencetoxicologymolecular neurodegenerationneuropharmacologymolecular pharmacologyphysiologyaddiction biologyneuropsychopharmacologyneurosciencefree radical biologyneuroimmunologyneurophysiologypharmacologydrug metabolismpharmacological researchmolecular psychiatryin vitro toxicology

Modulatory Effects of Chitosan Nanoparticles Against Alloxan-Induced Diabetes in Rats. Advances in Animal and Veterinary Sciences (2025)

diabetes therapycarbohydrate polymerdrug deliverynanoparticlesnanomedicinediabetespharmaceuticsdiabetic medicinebioactive compoundsbiomedical engineeringoxidative stresspharmacologybiomolecular engineeringnanoparticle researchbiomaterialscontrolled releasein vitro toxicology

Nanoparticle-Enhanced the Protective Effects of Mgn-3/Biobran Against Ehrlich Ascites Carcinoma-Induced Toxicity in the Liver, Kidneys, and Spleen of Mice. Mansoura Journal of Biology (2025)

future medicinal chemistrytoxicologydrug deliverynanomedicinemedicinal researchpharmaceuticsfree radical biologymedicinal chemistrybiochemistrybioactive compoundspharmacologytherapeutic targetsdrug metabolismphytotherapy researchcancer letterbiomolecular engineeringin vitro toxicology

Protective Effect of Biobran/Mgn-3, an Arabinoxylan From Rice Bran, Against the Cytotoxic Effects of Polyethylene Nanoplastics in Normal Mouse Hepatocytes: An in Vitro and in Silico Study. Nutrients (2025)

biological engineeringantioxidantstoxicologycontrolled releasephytotherapy researchdrug deliverynatural productspharmaceuticsbiopolymersbioactive compoundspharmacologybiomanufacturingbiomolecular engineeringcarbohydrate polymerbiomaterialsbiomimetic materialsin vitro toxicology

Protective Effects of Biobran/Mgn-3 Against Etoposide-Induced Immune Modulation and Hepatotoxicity in Male Rats. Journal of Applied Pharmaceutical Science (2025)

drug metabolisminflammationtoxicologyliver physiologymolecular pharmacologyneuropharmacologycell deathphysiologyimmunologymedicinal researchneuroimmunologypharmacologyoxidative stressfree radical biologyphytotherapy researchpharmacological researchin vitro toxicology

Anti-Radiation Effect of Mrn-100: A Hydro-Ferrate Fluid, in Vivo. Journal of Radiation Research (2024)

radiation oncologyabsorptionnanomedicinebiomedical engineeringnuclear medicineradiationin vitro toxicology