Faculty

Institution

Unit

Venue

Makarand Risbud

James J Maguire Jr Professor of Spine Research Orthopaedic Surgery

Thomas Jefferson University

Affiliations

Sidney Kimmel Medical College

Orthopaedic Surgery

Makarand Risbud is currently serving as an Orthopaedic Surgery James J Maguire Jr Professor of Spine Research Orthopaedic Surgery at Thomas Jefferson University.

Honors

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Experiences

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Education

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Makarand Risbud

Thomas Jefferson University

James J Maguire Jr Professor of Spine Research Orthopaedic Surgery

You can click a keyword to filter the displayed items

cell biology neuroscience intervertebral disc physiology membrane biology orthopedic surgery gene expression regenerative medicine vascular biology nucleus pulposus cells bone research genetics inflammation cellular physiology orthopaedic research liver physiology mammalian biology bone homeostasis tumor biology matrix biology medicinal research rheumatology cell signaling spinal cord musculoskeletal disorders cell regulation bone health spinal biomechanics spinal cord medicine spine surgery molecular physiology bone metabolism cell-matrix interactions nucleus pulposus protein science spine care intervertebral disc degeneration biological chemistry arthritis cytokines spinal disorders hypoxia (medicine) biological function cell death transcription regulation osmoregulation cellular senescence lumbar spine back pain treatment and prevention apoptosis matrix methods orthopedic biomechanics gene function skeletal muscle bone disease musculoskeletal research molecular regulation heme homeostasis protein function aging process inflammatory cytokines physical aging redox signaling matrix homeostasis hypoxic regulation catabolic effects organ culture system spine research aggrecan gene expression notochordal cells adult intervertebral disc glycosaminoglycan synthesis extracellular osmolarity human disc cells matrix remodeling stem cell research orthopaedic surgery developmental biology spine biomechanics biomedical engineering

Notable Scholarly Works

Notable Federal Grants

Collaborators

Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in Lg /J Mice. Aging Cell (2025)

Olivia K. OttoneJorge J. MundoBoahen N. KwakyeAmber SlaweskiJohn A. CollinsQinglin WuMargery A. ConnellyFatemeh NiaziorimiKoen van de WeteringMakarand V. Risbud

biologyageingaging processaging-associated diseasesaging cellcellular senescenceintervertebral disc

Skeletal and Dental Tissue Mineralization: The Potential Role of the Endoplasmic Reticulum/Golgi Complex and the Endolysosomal and Autophagic Transport Systems. Bone (2025)

Irving M ShapiroMakarand V RisbudTengteng TangWilliam J Landis

bone healthskeletal muscledental tissue mineralizationautophagytissue (biology)oral biologyautophagic transport systemsbone researchcell biologybone homeostasisbone metabolismbone disease

A New Perspective on Intervertebral Disc Calcification—From Bench to Bedside. Bone Research (2024)

Emanuel J. NovaisRajkishen NarayananJose A. CansecoKoen van de WeteringChristopher K. KeplerAlan S. HilibrandAlexander R. VaccaroMakarand V. Risbud

health sciencesorthopedic surgeryintervertebral disc calcificationbone researchradiologyorthopaedic surgery

Increased Hif-2α Activity in the Nucleus Pulposus Causes Intervertebral Disc Degeneration in the Aging Mouse Spine. Frontiers in Cell and Developmental Biology (2024)

Shira N. JohnstonMaria TsingasRahatul AinRuteja A. BarveMakarand V. Risbud

developmental sciencestructural biologyageingnucleus pulposusneuroscienceneuroscience of agingdevelopmental biologyneuroanatomycellular physiologyaging mouse spinedevelopmental neurobiologyneurophysiologymammalian biologycellular biologyintervertebral disc degenerationphysiology

Neuroimmune Changes Underscore Pain-Associated Behaviors and Disc Herniations in Sm/J Mice. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Emanuel J. NovaisOlivia K. OttoneEric V. BrownVedavathi MadhuVictoria A. TranAbhijit S. DigheMichael D. SolgaAlexandra ManchelAngelo C. LeporeMakarand V. Risbud

neurologyorthopedic surgeryneuroscienceneuroimmune changesupper extremityimmunologydisc herniationspain-associated behaviorsvascular biologymammalian biologyneuroimmunology

Opa1 Protects Intervertebral Disc and Knee Joint Health in Aged Mice by Maintaining the Structure and Metabolic Functions of Mitochondria. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Vedavathi MadhuMiriam Hernandaz-MeadowsAshley ColemanKimheak SaoKameron InguitoOwen HaslamPaige K BoneskiHiromi SesakiJohn A CollinsMakarand V. Risbud

orthopaedic researchjoint healthmusculoskeletal scienceintervertebral discregenerative medicineapplied physiologymusculoskeletal researchageingneurosciencevascular biologyspinal cord injuryorthopedic surgerymetabolic functionsmitochondrial functionexercise physiologyneuroscience of agingrehabilitationorthopedic biomechanicsmusculoskeletal disordersphysiology

Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia. Neurospine (2024)

Kimheak SaoMakarand V. Risbud

neurologyproteomicsdegenerative spineneuroscienceneuropharmacologyneurochemistrymolecular neurosciencebone researchvascular biologymedicinal researchcell biologyneurophysiologymammalian biologyneurodegenerative diseasesintervertebral disc degenerationskeletal dysplasiapathologic lesionsproteoglycan dysfunction

Role of Mitochondria in Intervertebral Disc Health and Disease. Orthopaedic Proceedings (2024)

M. V. Risbud

intervertebral disc healthintervertebral discorthopaedic surgeryorthopaedic research

Sdc4 Deletion Perturbs Intervertebral Disc Matrix Homeostasis and Promotes Early Osteopenia in the Aging Mouse Spine. Matrix Biology (2024)

Kimheak SaoMakarand V. Risbud

matrix biologyspinal cordorthopaedic researchintervertebral discregenerative medicinegeneticsmembrane biologyageingcell-matrix interactionsdevelopmental biologyspinal biomechanicsspine surgeryvascular biologyearly osteopeniaorthopedic surgeryspine carestructural biologyaging mouse spinebone researchorthopaedic surgery

Sirt6 Loss Causes Intervertebral Disc Degeneration in Mice by Promoting Senescence and Sasp Status. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Pranay RamtekeBahiyah WatsonMallory TociVictoria A TranShira JohnstonMaria TsingasRuteja A. BarveRamkrishna MitraRichard F. LoeserJohn A. CollinsMakarand V. Risbud

biologyageingsasp statusmolecular neurodegenerationmolecular biologycellular senescenceintervertebral discintervertebral disc degeneration

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Makarand Risbud

James J Maguire Jr Professor of Spine Research Orthopaedic Surgery

Thomas Jefferson University

Affiliations

Sidney Kimmel Medical College

Orthopaedic Surgery

Makarand Risbud is currently serving as an Orthopaedic Surgery James J Maguire Jr Professor of Spine Research Orthopaedic Surgery at Thomas Jefferson University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Makarand Risbud

Thomas Jefferson University

James J Maguire Jr Professor of Spine Research Orthopaedic Surgery

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in Lg /J Mice. Aging Cell (2025)

Olivia K. OttoneJorge J. MundoBoahen N. KwakyeAmber SlaweskiJohn A. CollinsQinglin WuMargery A. ConnellyFatemeh NiaziorimiKoen van de WeteringMakarand V. Risbud

biologyageingaging processaging-associated diseasesaging cellcellular senescenceintervertebral disc

Skeletal and Dental Tissue Mineralization: The Potential Role of the Endoplasmic Reticulum/Golgi Complex and the Endolysosomal and Autophagic Transport Systems. Bone (2025)

Irving M ShapiroMakarand V RisbudTengteng TangWilliam J Landis

bone healthskeletal muscledental tissue mineralizationautophagytissue (biology)oral biologyautophagic transport systemsbone researchcell biologybone homeostasisbone metabolismbone disease

A New Perspective on Intervertebral Disc Calcification—From Bench to Bedside. Bone Research (2024)

Emanuel J. NovaisRajkishen NarayananJose A. CansecoKoen van de WeteringChristopher K. KeplerAlan S. HilibrandAlexander R. VaccaroMakarand V. Risbud

health sciencesorthopedic surgeryintervertebral disc calcificationbone researchradiologyorthopaedic surgery

Increased Hif-2α Activity in the Nucleus Pulposus Causes Intervertebral Disc Degeneration in the Aging Mouse Spine. Frontiers in Cell and Developmental Biology (2024)

Shira N. JohnstonMaria TsingasRahatul AinRuteja A. BarveMakarand V. Risbud

Neuroimmune Changes Underscore Pain-Associated Behaviors and Disc Herniations in Sm/J Mice. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Emanuel J. NovaisOlivia K. OttoneEric V. BrownVedavathi MadhuVictoria A. TranAbhijit S. DigheMichael D. SolgaAlexandra ManchelAngelo C. LeporeMakarand V. Risbud

neurologyorthopedic surgeryneuroscienceneuroimmune changesupper extremityimmunologydisc herniationspain-associated behaviorsvascular biologymammalian biologyneuroimmunology

Opa1 Protects Intervertebral Disc and Knee Joint Health in Aged Mice by Maintaining the Structure and Metabolic Functions of Mitochondria. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Vedavathi MadhuMiriam Hernandaz-MeadowsAshley ColemanKimheak SaoKameron InguitoOwen HaslamPaige K BoneskiHiromi SesakiJohn A CollinsMakarand V. Risbud

Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia. Neurospine (2024)

Kimheak SaoMakarand V. Risbud

Role of Mitochondria in Intervertebral Disc Health and Disease. Orthopaedic Proceedings (2024)

M. V. Risbud

intervertebral disc healthintervertebral discorthopaedic surgeryorthopaedic research

Sdc4 Deletion Perturbs Intervertebral Disc Matrix Homeostasis and Promotes Early Osteopenia in the Aging Mouse Spine. Matrix Biology (2024)

Kimheak SaoMakarand V. Risbud

Sirt6 Loss Causes Intervertebral Disc Degeneration in Mice by Promoting Senescence and Sasp Status. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Pranay RamtekeBahiyah WatsonMallory TociVictoria A TranShira JohnstonMaria TsingasRuteja A. BarveRamkrishna MitraRichard F. LoeserJohn A. CollinsMakarand V. Risbud

biologyageingsasp statusmolecular neurodegenerationmolecular biologycellular senescenceintervertebral discintervertebral disc degeneration

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Carlos M. Isales

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Augusta University

endocrinology

metabolic health

Meghan McGee-Lawrence

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osteoporosis

skeletal homeostasis

Maurizio Pacifici

Institution

University of Pennsylvania

developmental biology

cell biology

Mark Hamrick

Institution

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regenerative medicine

physiology

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orthopaedic surgery

systemic scleroderma

Nicola C. Partridge

Institution

New York University

parathyroid gland

pharmacological research

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Johns Hopkins University

regenerative medicine

bone research

Charles J. Malemud

Institution

Case Western Reserve University

osteoarthritis

pathology

Vicki Rosen

Institution

Harvard University

bone research

regenerative medicine

Renato V. Iozzo

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matrix biology

pathology