Lucio Miele

Lucio Miele is a Professor at Louisiana State University Health Sciences Center, New Orleans, where he leads research in oncology and cancer biology. His work focuses on breast cancer, particularly triple-negative breast cancer, with emphasis on Notch signaling pathways, immunomodulation, and tumor immunology. Recent publications explore Cbl-b-Notch1 axis blockers to rewire immunosuppressive tumors, adeno-associated virus-mediated Notch targeting, and Tolvaptan as a potential anticancer agent. He also investigates adenosine signaling in double-negative T-cell responses, obesity-diabetes links to prostate cancer aggressiveness, and proteome-wide association studies for prostate cancer markers. His research integrates pharmacology, cell biology, and translational approaches to improve cancer care.