Linda Fabris

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Hematopoietic Biology And Malignancy

NoneLinda Fabris is currently serving as a Hematopoietic Biology And Malignancy faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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Linda Fabris

The University of Texas MD Anderson Cancer Center

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cell biology tumor biology oncogenes cancer cells molecular biology cancer research cancer biology molecular cell biology non-coding rna cell signaling molecular cancer signal transduction carcinogenesis gene expression long non-coding rna genetics breast cancer breast oncology cell regulation cancer discovery molecular diagnostics tumor suppressors microrna detection signaling pathways cancer genetics cellular physiology cell death medicinal research cancer genomics rna biology epigenetic changes systems biology biomarkers cellular biochemistry cancer growth oncogenic agent cell proliferation epigenomics surgical oncology developmental cell protein science biological chemistry matrix biology thoracic oncology biomarker discovery tumor targeting cancer immunosurveillance cellular structure intracellular trafficking protein transport organelle dynamics cell cycle protein function molecular pathways molecular regulation cell physiology bronchial neoplasm anti-cancer agents small rna therapeutic efficacy prostate cancer biomarkers key modulators tumor immune response microtubule-dependent lipid raft egf pathway surgical trauma cell cycle entry mt stability free xeno‐micrornas t198 modification p27kip1 protein stability selective mirna era-positive breast cancer renal cell carcinoma clinical biomarkers potential implications

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1366: Cyp4a22-As1-Ybx1 Axis Drives Radiation Resistance in Cervical Adenocarcinoma via Pgk1 Transactivation.. Cancer Research (2026)

cancer geneticspgk1 transactivationradiation oncologycancer researchgynecologic oncologyradiation biologycervical adenocarcinomacervical cancercancer cellsoncogenescyp4a22-as1-ybx1 axis drivescancer biologytumor biologycell biology

Ep31670, a Dual-Bet + P300 Inhibitor, Demonstrates Pre-Clinical Efficacy, Including in Combination With Jak Inhibition, in the Hmplw515L Adoptive Transfer Model of Myelofibrosis (Mf). Blood (2025)

immunologyhematological malignanciesjak inhibitionleukemiapharmacologymyeloid neoplasiahematologymolecular cancernovel therapiestherapeutic targetsbone marrow transplantationoncogenesmedicinal researchpre-clinical efficacyexperimental medicinecell biology

The Mutational Landscape and Functional Effects of Noncoding Ultraconserved Elements in Human Cancers. Science Advances (2025)

Recep BayraktarYitao TangMihnea P. DragomirCristina IvanXinxin PengLinda FabrisJianhua ZhangAlessandro CarugoSerena AneliJintan LiuMei-Ju M. ChenSanjana SrinivasanIman SahnouneEmine BayraktarKadir C. AkdemirMeng ChenPranav NarayananWilson HuangLeonie Florence OttAgda Karina EterovicOscar Eduardo VillarrealMohammad Moustaf MohammadMichael D. PeoplesDanielle M. WalshJon Andrew HernandezMargaret B. MorganKenna R. ShawJennifer S. DavisDavid MenterConstantine S. TamPaul YehSarah-Jane DawsonLaura Z. RassentiThomas J. KippsTanja KunejZeev EstrovSimon A. JoosseLuca PaganiCatherine Alix-PanabièresKlaus PantelAlessandra FerajoliAndrew FutrealIgnacio I. WistubaMilan RadovichScott KopetzMichael J. KeatingGiulio F. DraettaJohn S. MattickHan LiangGeorge A. Calin

functional effectsultraconserved elementsscience advancemutational landscapehuman cancers

Mir-543 Regulates the Epigenetic Landscape of Myelofibrosis by Targeting Tet1 and Tet2. JCI Insight (2024)

gene expressionleukemiamyeloid neoplasianon-coding rnamolecular cancerepigenetic changesgeneticsmolecular cell biologymolecular diagnosticsoncogenescancer cellsepigeneticsepigenetic landscapecell biology

17β-Estradiol Promotes Extracellular Vesicle Release and Selective Mirna Loading in Erα-Positive Breast Cancer. Proceedings of the National Academy of Sciences (2023)

Rares DrulaBarbara PardiniXiao FuMireia Cruz De los SantosAncuta JurjLan PangSherien M. El-DalyLinda FabrisErik KnutsenMihnea P. DragomirRecep BayraktarYongfeng LiMeng ChenFilippo Del VecchioLéa BerlandJessica DaeDaniel FanMasayoshi ShimizuAnh M. TranMercedes BarziCarlotta PioppiniAngelica M. GutierrezCristina IvanSalyna MeasCarolyn S. HallSuresh K. AlahariIoana Berindan-NeagoeMuller FabbriAnthony LucciBanu ArunSimone AnfossiGeorge A. Calin

selective mirnaera-positive breast cancerbreast cancercancer cellscell biologytumor biologybreast oncology

Abstract 3795: Deciphering the in Vivo Roles of a Novel Long Non-Coding Rna in Chronic Lymphocytic Leukemia and Richter Syndrome. Cancer Research (2023)

hematological malignanciespathologycell biologyabstract 3795transcription factorsmolecular cell biologymolecular diagnosticslong non-coding rnanucleic acidsleukemiarna processingtranscription (biology)chronic lymphocytic leukemiatranscriptomegene expressionnon-coding rnamolecular biologyoncogenesrna biologymolecular medicine

Abstract 3799: Regulation of P16-E2F1-Cdk4/6 Signaling by Truc-16 Ultraconserved Long Non-Coding Rna. Cancer Research (2023)

abstract 3799gene expressiontranscription regulationp16-e2f1-cdk4/6 signalingnon-coding rnacell signalingmolecular and cellular biologytranscription factorscell researchmolecular cell biologynucleic acidslong non-coding rnamolecular biologyoncogenesrna biologysignal transductioncell biology

Abstract 5750: The Mutational Landscape of Ultraconserved Elements in Human Cancers. Cancer Research (2023)

Recep BayraktarYitao TangMihnea P. DragomirLinda FabrisGiulio F. DraettaHan LiangGeorge A. Calin

cancer researchultraconserved elementsmutational landscapehuman cancers

Circulating Non-Coding Rnas in Renal Cell Carcinoma—Pathogenesis and Potential Implications as Clinical Biomarkers. Frontiers in Cell and Developmental Biology (2020)

Dominik A. BarthRares DrulaLeonie OttLinda FabrisOndrej SlabyGeorge A. CalinMartin Pichler

carcinogenesisbiomarkersnon-coding rnaclinical biomarkerssystems biologypotential implicationscancer discoverylong non-coding rnakidney cancerdevelopmental biologytumor biologyrenal cell carcinomacell biology

N-Blr, a Primate-Specific Non-Coding Transcript Leads to Colorectal Cancer Invasion and Migration. UNC Libraries (2020)

carcinogenesiscancer geneticscancer researchmolecular cancercancer genomicsmolecular diagnosticsoncogenescancer cellscolorectal cancerprimate-specific non-coding transcriptcancer biologypathologytumor biologycolorectal cancer invasioncell biology