Faculty

Institution

Unit

Venue

Deborah Leckband

Reid T Milner Professor

UIUC

Affiliations

The Grainger College of Engineering

Bioengineering

Department of Bioengineering

College of Liberal Arts & Sciences

Department of Chemical and Biomolecular Engineering

School of Chemical Sciences

Department of Chemical and Biomolecular Engineering

Deborah Leckband is currently serving as a Bioengineering Reid T Milner Professor at Uiuc.

Honors

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Experiences

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Education

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Deborah Leckband

UIUC

Reid T Milner Professor

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biophysics cell biology cell adhesion cellular physiology biological macromolecules matrix biology adhesion molecular biology protein science molecular cell biology mechanobiology cellular biochemistry cell signaling biophysical chemistry biomolecular engineering signal transduction molecular biophysics biomolecular interactions cell biomechanics biopolymers biomolecules cell-matrix interactions single molecule biophysics polymer science biophysical review polymeric surface structural molecular biology experimental biophysics cell interactions interface science biomolecular structure vascular biology mechanotransduction proteinlipid interaction signaling pathways membrane science molecular structure macromolecular science protein adsorption polymer testing macromolecular chemistry protein assembly protein chemistry endothelial dysfunction carbohydrate-protein interactions adhesive material surface functionalization cell motility amphiphilic system lipid movement ethylene glycol altmetric attention score cadherin adhesion protein refolding surface modification therapeutic nanomaterials polymer technology protein function molecular mechanics surface force apparatus adhesion proteins direct force measurements biochemical interaction analytical microsystems lab-on-a-chip biomolecular analysis intercellular adhesion force transduction surface nanotechnology molecular weight polyethylene glycol adhesion forces atomic force microscope grafting density ethylene oxide tissue morphogenesis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cadherins and Growth Factor Receptors: Ligand Selective Mechano-Switches at Cadherin Junctions. Journal of Cell Science (2025)

Vinh VuBrendan SullivanEvan HebnerZainab RahilYubo ZouDeborah Leckband

signaling pathwaysreceptorscellular physiologycell signalingsystems biologyforce transduction cascadescell biomechanicsmolecular cell biologymechanotransductionmechanobiologycell adhesionsignal transductionforce transductiongrowth factor receptorscell biology

Epidermal Growth Factor Receptor is an Essential Component in E-Cadherin Force-Transduction Complexes. Journal of Cell Science (2025)

Yubo ZouNicolas AllenEmaan RaufDeborah Leckband

e-cadherin force-transduction complexescell signalingextracellular matrixcell biologycytoskeletoncell interactionsmatrix biologymolecular cell biologyengineered cadherin mutantscellular physiologycadherin force transductionmolecular and cellular biologycell-matrix interactionsmolecular physiologycellular biochemistrysignaling pathwayssystems biologycell adhesionsignal transduction

Computational and Experimental Approaches to Quantify Protein Binding Interactions Under Confinement. Biophysical Journal (2024)

Deborah LeckbandDaniel K. SchwartzYinghao Wu

computational biophysicsbiomolecular interactionsmolecular biophysicsbiophysicsbiophysical reviewprotein modelingprotein structuremolecular modellingexperimental approachesmolecular dockingmolecular biologyprotein science

Editorial Overview: Biomechanics and Mechanobiology: Mechano-Genomics. Current Opinion in Biomedical Engineering (2024)

Deborah LeckbandMohammad R.K. Mofrad

editorial overviewkinesiologyorthopedic biomechanicsmechanotransductionmechanobiologybiomechanicsmechanical science

A Computational Study for Understanding the Impact of P120-Catenin on the Cis -Dimerization of Cadherin. Journal of Molecular Cell Biology (2023)

Zhaoqian SuVinh H VuDeborah E LeckbandYinghao Wu

biomolecular interactionsbiophysicscytoskeletoncell surfacemolecular modellingmolecular dockingmolecular biologycell adhesionprotein sciencecellular biochemistrycell surface receptorsconformational dynamics

Cadherins and Growth Factor Receptors: Signaling Mechano-Switches at Intercellular Junctions. Current Opinion in Biomedical Engineering (2023)

Deborah Leckband

signaling pathwaysreceptorscellular physiologycell signalingmatrix biologyintercellular communicationcell-matrix interactionsmechanobiologydevelopmental biologysignal transductiongrowth factor receptorscell biology

Development of Microfluidic Platform That Enables ‘On-Chip’ Imaging of Cells Exposed to Shear Stress and Cyclic Stretch. Microfluidics and Nanofluidics (2023)

Whitney E. SinclairAshtamurthy S. PawateTy’Nya A. LarryJeremy M. SchiefersteinJoseph J. WhittenbergDeborah E. LeckbandPaul J. A. Kenis

cell engineeringcyclic stretchbiomedical engineeringmicrofluidicsmicrofluidic platformmicroscale systemlab-on-a-chiporgan-on-a-chipmechanobiologymicroscopybiological imagingbiomedical imagingbiofabricationcell biology

Mechanical Activation of Epidermal Growth Factor Receptor at Intercellular Adhesions. Biophysical Journal (2023)

Deborah E. LeckbandVinh H. VuYubo ZouBrendan G. Sullivan

cellular physiologycytoskeletonmechanical activationmatrix biologycell-matrix interactionsmechanobiologycell adhesiondevelopmental biologyadhesionwound healingextracellular matrixcell biology

Protein Folding Stability and Kinetics in Alginate Hydrogels. Biomacromolecules (2023)

Roger ChangMartin GruebeleDeborah E. Leckband

biophysical chemistrybiophysicsmolecular biophysicsbiological macromoleculesprotein refoldingprotein chemistrybiopolymer gelalginate hydrogelsunfolding kineticsprotein structuregel encapsulationbiomolecular engineeringbiomaterialsprotein scienceprotein engineeringbiopolymersprotein folding

Extracellular Matrix Regulates Force Transduction at Ve-Cadherin Junctions. Molecular Biology of the Cell (2022)

Xinyu KongAdrian KapustkaBrendan SullivanGregory J. SchwarzDeborah E. Leckband

receptorscellular physiologycytoskeletonsystems biologycell signalingcell biomechanicssignal cascadesmolecular cell biologymatrix biologycell-matrix interactionsmechanobiologycell adhesionsignal transductionforce transductionextracellular matrixcell biology

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Deborah Leckband

Reid T Milner Professor

UIUC

Affiliations

The Grainger College of Engineering

Bioengineering

Department of Bioengineering

College of Liberal Arts & Sciences

Department of Chemical and Biomolecular Engineering

School of Chemical Sciences

Department of Chemical and Biomolecular Engineering

Deborah Leckband is currently serving as a Bioengineering Reid T Milner Professor at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Deborah Leckband

UIUC

Reid T Milner Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cadherins and Growth Factor Receptors: Ligand Selective Mechano-Switches at Cadherin Junctions. Journal of Cell Science (2025)

Vinh VuBrendan SullivanEvan HebnerZainab RahilYubo ZouDeborah Leckband

Epidermal Growth Factor Receptor is an Essential Component in E-Cadherin Force-Transduction Complexes. Journal of Cell Science (2025)

Yubo ZouNicolas AllenEmaan RaufDeborah Leckband

Computational and Experimental Approaches to Quantify Protein Binding Interactions Under Confinement. Biophysical Journal (2024)

Deborah LeckbandDaniel K. SchwartzYinghao Wu

Editorial Overview: Biomechanics and Mechanobiology: Mechano-Genomics. Current Opinion in Biomedical Engineering (2024)

Deborah LeckbandMohammad R.K. Mofrad

editorial overviewkinesiologyorthopedic biomechanicsmechanotransductionmechanobiologybiomechanicsmechanical science

A Computational Study for Understanding the Impact of P120-Catenin on the Cis -Dimerization of Cadherin. Journal of Molecular Cell Biology (2023)

Zhaoqian SuVinh H VuDeborah E LeckbandYinghao Wu

Cadherins and Growth Factor Receptors: Signaling Mechano-Switches at Intercellular Junctions. Current Opinion in Biomedical Engineering (2023)

Deborah Leckband

Development of Microfluidic Platform That Enables ‘On-Chip’ Imaging of Cells Exposed to Shear Stress and Cyclic Stretch. Microfluidics and Nanofluidics (2023)

Whitney E. SinclairAshtamurthy S. PawateTy’Nya A. LarryJeremy M. SchiefersteinJoseph J. WhittenbergDeborah E. LeckbandPaul J. A. Kenis

Mechanical Activation of Epidermal Growth Factor Receptor at Intercellular Adhesions. Biophysical Journal (2023)

Deborah E. LeckbandVinh H. VuYubo ZouBrendan G. Sullivan

cellular physiologycytoskeletonmechanical activationmatrix biologycell-matrix interactionsmechanobiologycell adhesiondevelopmental biologyadhesionwound healingextracellular matrixcell biology

Protein Folding Stability and Kinetics in Alginate Hydrogels. Biomacromolecules (2023)

Roger ChangMartin GruebeleDeborah E. Leckband

Extracellular Matrix Regulates Force Transduction at Ve-Cadherin Junctions. Molecular Biology of the Cell (2022)

Xinyu KongAdrian KapustkaBrendan SullivanGregory J. SchwarzDeborah E. Leckband

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4
5
34
10 / page