Faculty

Institution

Unit

Venue

Laurent Brossay

Charles A and Helen B Stuart Professor of Medical Science Professor of Molecular Microbiology and Immunology

Brown University

Affiliations

Division of Biology and Medicine

Molecular Biology, Cell Biology, and Biochemistry

Molecular Microbiology and Immunology

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Molecular Microbiology and Immunology

Laurent Brossay is currently serving as a Division Of Biology And Medicine Charles A and Helen B Stuart Professor of Medical Science Professor of Molecular Microbiology and Immunology at Brown University.

Honors

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Experiences

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Education

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Laurent Brossay

Brown University

Charles A and Helen B Stuart Professor of Medical Science Professor of Molecular Microbiology and Immunology

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immunology immune responses cell biology adaptive immune system cell signaling cellular immune responses innate immune system gene expression mammalian biology molecular immunology t-regulatory cell virology medicine clinical microbiology molecular biology receptors clinical immunology host response nk cells microbial pathogenesis inflammation medicinal research cytokines virus-host interactions hematology immunochemistry lymphocyte development host factors venereology histocompatibility experimental medicine cellular therapy bacteriology veterinary microbiology experimental biology tissue development viral infection nkt cells antigen presentation submandibular gland stem cell research molecular cell biology cell death general virology molecular microbiology antigen processing tolerance induction cell culture viral genetics host genetics protein function immunogenetics pathogen characterization cancer biology natural killer cells structural requirements antigen-presenting function reproductive immunology proteome research clinical proteomics cellular biochemistry medical virology histopathology microbial genetics glycosylation granulocyte inhibitory activity cell migration mammalian evolution viral infections innate defense present glycolipids natural transformation simultaneous defects pilt mutations cytokine synthesis cytokine signaling infectious diseases immunity (medicine)

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tissue-Resident Nk Cells Do Their Own Glandscaping. The Journal of Experimental Medicine (2025)

Jacob A. MyersShanelle P. ReillyLaurent Brossay

tissue-resident nk cellsimmunologyexperimental medicineexperimental biology

Nk Cells Restrain Cytotoxic Cd8 + T Cells in the Submandibular Gland via Pd-1–Pd-L1. Science Immunology (2024)

Samantha M. BorysShanelle P. ReillyIan MagillDavid ZemmourLaurent Brossay

nk cellsmolecular immunologyimmunopathologycell signalingimmunologyhost responsesubmandibular glandimmune responsesimmunity (medicine)adaptive immune systemcellular immune responses

Cryptic Mhc-E Epitope From Influenza Elicits a Potent Cytolytic T Cell Response. Nature Immunology (2023)

Michael J. HoganNikita MaheshwariBridget E. BeggAnnalisa NicastriEmma J. HedgepethHiromi MuramatsuNorbert PardiMichael A. MillerShanelle P. ReillyLaurent BrossayKristen W. LynchNicola TernetteLaurence C. Eisenlohr

infectious diseasest-regulatory cellimmunologycryptic mhc-eimmune responsesmedicineadaptive immune systeminfluenza

Determining Antitumor Responses to Variable Cadherin Expression. The Journal of Immunology (2023)

Alexander R.D JordonCéline FugereSamantha BorysLaurent Brossay

variable cadherin expressioncancer immunotherapyimmunologyantitumor responsespharmacology

Pd-1 Mediated Regulation of Cd8+ T Cells in the Murine Submandibular Gland. The Journal of Immunology (2023)

Samantha BorysDavid ZemmourT ImmGenLaurent Brossay

t-regulatory cellcancer immunotherapycell signalingimmunologycell biologyimmune mediatorsimmunotherapydermatologypeptidesimmune responsescellular immune responsesmucosal immunologyadaptive immune systemmurine submandibular glandreceptors

Pd-1 Mediated Regulation of Unique Activated Cd8 + T Cells by Nk Cells in the Submandibular Gland. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Samantha M. BorysShanelle P. ReillyIan MagillDavid ZemmourLaurent Brossay

nk cellshost factorscell signalingimmunologycell biologyhost responsedermatologysubmandibular glandpeptidesimmune responsescellular immune responsesadaptive immune systemfunctional regulationgene expressionreceptors

The Antigen Presentation of MCMV Specific Qa-1-Restricted Cd8 +T Cells. The Journal of Immunology (2023)

Shanelle ReillyDelia DemersCeline FugereLaurent Brossay

epidemiologyimmunologyimmune responseshost factorsantigen presentation

Innate Lymphoid Cells; Essential Responders to Pulmonary Cytomegalovirus Infection. The Journal of Immunology (2022)

Miles Alexander MundyLaurent Brossay

public healthimmunologyrespiratory medicineimmune responsespulmonary cytomegalovirus infectionessential respondersveterinary medicineinnate lymphoid cellsemergency medicineinnate immune system

The Characterization of MCMV Specific Qa-1-Restricted Cd8+ T Cells. The Journal of Immunology (2022)

Shanelle ReillyCourtney AndersonLaurent Brossay

molecular immunologyt-regulatory cellimmunologycell biologysingle-cell analysismicrobiologyimmune responsescellular immune responsesadaptive immune systemgene expressionreceptors

The Role of Immune Checkpoint Pd-1 in the Submandibular Gland. The Journal of Immunology (2022)

Samantha BorysLaurent Brossay

immunologysubmandibular glandimmunotherapyimmune checkpoint inhibitorsclinical immunology

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Laurent Brossay

Charles A and Helen B Stuart Professor of Medical Science Professor of Molecular Microbiology and Immunology

Brown University

Affiliations

Division of Biology and Medicine

Molecular Biology, Cell Biology, and Biochemistry

Molecular Microbiology and Immunology

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Molecular Microbiology and Immunology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Laurent Brossay

Brown University

Charles A and Helen B Stuart Professor of Medical Science Professor of Molecular Microbiology and Immunology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tissue-Resident Nk Cells Do Their Own Glandscaping. The Journal of Experimental Medicine (2025)

Jacob A. MyersShanelle P. ReillyLaurent Brossay

tissue-resident nk cellsimmunologyexperimental medicineexperimental biology

Nk Cells Restrain Cytotoxic Cd8 + T Cells in the Submandibular Gland via Pd-1–Pd-L1. Science Immunology (2024)

Samantha M. BorysShanelle P. ReillyIan MagillDavid ZemmourLaurent Brossay

nk cellsmolecular immunologyimmunopathologycell signalingimmunologyhost responsesubmandibular glandimmune responsesimmunity (medicine)adaptive immune systemcellular immune responses

Cryptic Mhc-E Epitope From Influenza Elicits a Potent Cytolytic T Cell Response. Nature Immunology (2023)

infectious diseasest-regulatory cellimmunologycryptic mhc-eimmune responsesmedicineadaptive immune systeminfluenza

Determining Antitumor Responses to Variable Cadherin Expression. The Journal of Immunology (2023)

Alexander R.D JordonCéline FugereSamantha BorysLaurent Brossay

variable cadherin expressioncancer immunotherapyimmunologyantitumor responsespharmacology

Pd-1 Mediated Regulation of Cd8+ T Cells in the Murine Submandibular Gland. The Journal of Immunology (2023)

Samantha BorysDavid ZemmourT ImmGenLaurent Brossay

Pd-1 Mediated Regulation of Unique Activated Cd8 + T Cells by Nk Cells in the Submandibular Gland. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Samantha M. BorysShanelle P. ReillyIan MagillDavid ZemmourLaurent Brossay

The Antigen Presentation of MCMV Specific Qa-1-Restricted Cd8 +T Cells. The Journal of Immunology (2023)

Shanelle ReillyDelia DemersCeline FugereLaurent Brossay

epidemiologyimmunologyimmune responseshost factorsantigen presentation

Innate Lymphoid Cells; Essential Responders to Pulmonary Cytomegalovirus Infection. The Journal of Immunology (2022)

Miles Alexander MundyLaurent Brossay

public healthimmunologyrespiratory medicineimmune responsespulmonary cytomegalovirus infectionessential respondersveterinary medicineinnate lymphoid cellsemergency medicineinnate immune system

The Characterization of MCMV Specific Qa-1-Restricted Cd8+ T Cells. The Journal of Immunology (2022)

Shanelle ReillyCourtney AndersonLaurent Brossay

molecular immunologyt-regulatory cellimmunologycell biologysingle-cell analysismicrobiologyimmune responsescellular immune responsesadaptive immune systemgene expressionreceptors

The Role of Immune Checkpoint Pd-1 in the Submandibular Gland. The Journal of Immunology (2022)

Samantha BorysLaurent Brossay

immunologysubmandibular glandimmunotherapyimmune checkpoint inhibitorsclinical immunology

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10 / page

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Institution

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human diseases

nanoparticle research

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Case Western Reserve University

clinical immunology

tuberculosis

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t-regulatory cell

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gene discovery

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