Faculty

Institution

Unit

Venue

J. Lawrence Marsh

Professor Developmental & Cell Biology Director Developmental Biology Center

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Developmental and Cell Biology

J. Lawrence Marsh is currently serving as a Developmental And Cell Biology Professor Developmental & Cell Biology Director Developmental Biology Center at University of California, Irvine.

Honors

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Experiences

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Education

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J. Lawrence Marsh

University of California, Irvine

Professor Developmental & Cell Biology Director Developmental Biology Center

You can click a keyword to filter the displayed items

genetics neuroscience molecular biology huntington's disease insect molecular biology pharmacology molecular genetics gene expression genomics avian biology neuropharmacology signal transduction mammalian biology human genetics structural biology genome biology molecular cell biology molecular neurodegeneration protein science insect science cancer genetics medical genetics embryonic development gene regulation cancer biology medicinal research animal genetics developmental genetics cell regulation neuroprotection molecular neurobiology huntington disease cell death enzyme inhibition oncogenes signaling pathways gene function cellular neurobiology protein genetics gene structure evolutionary genetics colorectal cancer molecular regulation dopa decarboxylase drosophila melanogaster colon cancer cellular biochemistry molecular physiology peptide science animal science protein function protein chemistry in vivo systems pathway analysis epigenomics transcription regulation sequence analysis breast oncology cancer genomics brain science gene evolution hypersensitivity chromosome biology cytogenetics twisted gastrulation drosophila model polyglutamine aggregation germ line developmental expression drosophila species polyglutamine diseases polyglutamine-dependent neurodegeneration histone deacetylase inhibitors mouse model histone deacetylase inhibitor suberoylanilide hydroxamic acid cellular senescence cell signaling degenerative disease developmental biology abnormal growth cell biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cavitation Bubble Dynamics Using a Shock Tube Model for Blast Injury Research. Journal of Dynamic Behavior of Materials (2024)

J. L. MarshL. ZinnelS. A. Bentil

numerical simulationsfiberstraumaaerospace engineeringapplied physicsnonlinear dynamicsmechanical engineeringcavitating flowsmechanical behaviorhydrodynamic cavitationcavitation bubble dynamicsshock wavesblast engineeringmechanics of materialsfluid dynamicsblast injury researchshock tube modelrheologybubble dynamicsfluid mechanics

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model. Frontiers in Neuroscience (2022)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaJ. Lawrence MarshAli Khoshnan

neurologypathogenesisdrosophila modelavian biologygeneticsmammalian biologyanimal sciencegut bacteriahuntington's diseaseneuroscience

Effects of Flanking Sequences and Cellular Context on Subcellular Behavior and Pathology of Mutant Htt. Human Molecular Genetics (2020)

Anjalika ChongthamDouglas J BornemannBrett A BarbaroTamas LukacsovichNamita AgrawalAdeela SyedShane WorthgeJudith PurcellJohn BurkeTheodore M ChinJ Lawrence Marsh

genomicsgenome biologysubcellular behaviorgeneticsmutant httmolecular geneticsmolecular biologycellular contextpathologyhuman genetics

Serine Residues 13 and 16 Are Key Modulators of Mutant Huntingtin Induced Toxicity in Drosophila. Experimental Neurology (2020)

Megha ChatterjeeJoan S. SteffanTamas LukacsovichJ. Lawrence MarshNamita Agrawal

neurologyavian biologygeneticsmammalian biologyneuropharmacologymolecular regulationkey modulatorsinsect molecular biologyneurosciencegene regulation

Miles to Go (Mtgo) Encodes Fndc3 Proteins That Interact With the Chaperonin Subunit Cct3 and Are Required for Nmj Branching and Growth in Drosophila. Developmental Biology (2018)

Adeela SyedTamás LukacsovichMiles PomeroyA. Jane BardwellGentry Thomas DeckerKatrina G. WaymireJudith PurcellWeijian HuangJames GuiEmily M. PadillaCindy ParkAntor PaulThai Bin T. PhamYanete RodriguezStephen WeiShane WorthgeRonak ZebarjediBing ZhangLee BardwellJ. Lawrence MarshGrant R. MacGregor

nmj branchinggeneticsdevelopmental biology

Nonmammalian Models of Huntington’s Disease. Methods in molecular biology (2018)

Anjalika ChongthamBrett BarbaroTomas FilipAdeela SyedWeijian HuangMarianne R. SmithJ. Lawrence Marsh

huntington's diseasemolecular biologygeneticsnonmammalian models

Systematic Genetic Interaction Studies Identify Histone Demethylase Utx as Potential Target for Ameliorating Huntington’s Disease. Human Molecular Genetics (2018)

Wan SongNóra ZsindelyAnikó FaragóJ Lawrence MarshLászló Bodai

histone demethylase utxgeneticsmedical geneticshuntington's diseasepotential target

Letter to the Editor - Round Table Unites Totackle Culture Change in an Effort to Improve Animal Research Reporting. BMC Veterinary Research (2017)

Nicola J. OsborneMerel Ritskes-HoitingaAmrita AhluwahliaSabina AlamMatthew BrownHayley HendersonWim de LeeuwJoan MarshDavid MoherErica van OortFrances RawleBeat M. RiedererJose Sanchez-MorgadoEmily S. SenaCaroline StruthersMatthew WestmoreMarc T. AveyRony KalmanAnnette O’ConnorJan SargeantAnja PetrieAdrian Smith

veterinary researchround table unitesculture change

Phosphorylation of Huntingtin at Residue T3 is Decreased in Huntington’s Disease and Modulates Mutant Huntingtin Protein Conformation. Proceedings of the National Academy of Sciences (2017)

Cristina CariuloLucia AzzolliniMargherita VeraniPaola MartufiRoberto BoggioAnass ChikiSean M. DeguireMarta CherubiniSilvia GinesJ. Lawrence MarshPaola ConfortiElena CattaneoIolanda SantimoneFerdinando SquitieriHilal A. LashuelLara PetriccaAndrea Caricasole

biophysicsgeneticsstructural biologyprotein sciencehuntington's diseasebiochemistry

Polyglutamine Expansion Affects Huntingtin Conformation in Multiple Huntington’s Disease Models. Scientific Reports (2017)

Manuel DaldinValentina FodaleCristina CariuloLucia AzzolliniMargherita VeraniPaola MartufiMaria Carolina SpieziaSean M. DeguireMarta CherubiniDouglas MacdonaldAndreas WeissAlberto BrescianiJean-Paul Gerard VonsattelLara PetriccaJ. Lawrence MarshSilvia GinesIolanda SantimoneMassimo MaranoHilal A. LashuelFerdinando SquitieriAndrea Caricasole

neurologyhuntington's diseasebiophysicsneuroscience

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J. Lawrence Marsh

Professor Developmental & Cell Biology Director Developmental Biology Center

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Developmental and Cell Biology

J. Lawrence Marsh is currently serving as a Developmental And Cell Biology Professor Developmental & Cell Biology Director Developmental Biology Center at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

J. Lawrence Marsh

University of California, Irvine

Professor Developmental & Cell Biology Director Developmental Biology Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cavitation Bubble Dynamics Using a Shock Tube Model for Blast Injury Research. Journal of Dynamic Behavior of Materials (2024)

J. L. MarshL. ZinnelS. A. Bentil

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model. Frontiers in Neuroscience (2022)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaJ. Lawrence MarshAli Khoshnan

neurologypathogenesisdrosophila modelavian biologygeneticsmammalian biologyanimal sciencegut bacteriahuntington's diseaseneuroscience

Effects of Flanking Sequences and Cellular Context on Subcellular Behavior and Pathology of Mutant Htt. Human Molecular Genetics (2020)

Anjalika ChongthamDouglas J BornemannBrett A BarbaroTamas LukacsovichNamita AgrawalAdeela SyedShane WorthgeJudith PurcellJohn BurkeTheodore M ChinJ Lawrence Marsh

genomicsgenome biologysubcellular behaviorgeneticsmutant httmolecular geneticsmolecular biologycellular contextpathologyhuman genetics

Serine Residues 13 and 16 Are Key Modulators of Mutant Huntingtin Induced Toxicity in Drosophila. Experimental Neurology (2020)

Megha ChatterjeeJoan S. SteffanTamas LukacsovichJ. Lawrence MarshNamita Agrawal

neurologyavian biologygeneticsmammalian biologyneuropharmacologymolecular regulationkey modulatorsinsect molecular biologyneurosciencegene regulation

Miles to Go (Mtgo) Encodes Fndc3 Proteins That Interact With the Chaperonin Subunit Cct3 and Are Required for Nmj Branching and Growth in Drosophila. Developmental Biology (2018)

nmj branchinggeneticsdevelopmental biology

Nonmammalian Models of Huntington’s Disease. Methods in molecular biology (2018)

Anjalika ChongthamBrett BarbaroTomas FilipAdeela SyedWeijian HuangMarianne R. SmithJ. Lawrence Marsh

huntington's diseasemolecular biologygeneticsnonmammalian models

Systematic Genetic Interaction Studies Identify Histone Demethylase Utx as Potential Target for Ameliorating Huntington’s Disease. Human Molecular Genetics (2018)

Wan SongNóra ZsindelyAnikó FaragóJ Lawrence MarshLászló Bodai

histone demethylase utxgeneticsmedical geneticshuntington's diseasepotential target

Letter to the Editor - Round Table Unites Totackle Culture Change in an Effort to Improve Animal Research Reporting. BMC Veterinary Research (2017)

veterinary researchround table unitesculture change

Phosphorylation of Huntingtin at Residue T3 is Decreased in Huntington’s Disease and Modulates Mutant Huntingtin Protein Conformation. Proceedings of the National Academy of Sciences (2017)

biophysicsgeneticsstructural biologyprotein sciencehuntington's diseasebiochemistry

Polyglutamine Expansion Affects Huntingtin Conformation in Multiple Huntington’s Disease Models. Scientific Reports (2017)

neurologyhuntington's diseasebiophysicsneuroscience

1
2
3
4
5
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10 / page

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