Faculty

Institution

Unit

Venue

Lawrence Lash

Professor of Pharmacology

Wayne State University

Affiliations

Graduate School

School of Medicine

Pharmacology

Lawrence Lash is currently serving as a Graduate School Professor of Pharmacology at Wayne State University.

Honors

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Experiences

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Education

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Lawrence Lash

Wayne State University

Professor of Pharmacology

You can click a keyword to filter the displayed items

pharmacology toxicology nephrology membrane biology urology redox biology biochemistry physiology renal function medicinal research mitochondrial function liver physiology renal pathophysiology inflammation drug metabolism metabolism endocrinology environmental toxicology mammalian biology cellular physiology pharmacotherapy hepatotoxicity apoptosis protein science vascular biology clinical toxicology applied pharmacology regulatory toxicology experimental toxicology enzyme inhibition membrane transport protein transport primary cultures analytical toxicology cell metabolism cellular biochemistry in vitro toxicology experimental pharmacology nutrient physiology clinical pharmacology metal toxicity biochemical sciences inhalation toxicology secondary metabolism inorganic mercury redox signaling rat kidney pharmacokinetics comparative toxicology renal care distal tubular cells environmental exposures respiratory toxicology neurochemistry mitochondrial dysfunction treatment effects cell culture trace elements phytotoxicity toxinology glutathione transport mitochondrial glutathione human exposure experimental biophysics clinical medicine trace metals mitochondrial glutathione transport mercuric chloride glutathione metabolism uninephrectomized rats glutathione status occupational exposure urinary biomarkers human sciences exogenous glutathione renal glutathione transport

Notable Scholarly Works

Notable Federal Grants

Collaborators

Biomarkers for Exposure to Nephrotoxic Environmental Chemicals and Drugs Derived From Exosomes Secreted From Human Proximal Tubular Cells (Abstract Id: 230199). Journal of Pharmacology and Experimental Therapeutics (2026)

in vitro toxicologyextracellular microvesiclesbiomarkerspharmacologytoxicologytoxicological mechanismpharmacological researchbiochemistrycell biology

A Novel Model System to Predict Efficacy and Safety of Dexamethasone. Journal of Pharmacology and Experimental Therapeutics (2025)

medicinepharmacologypharmacotherapyapplied pharmacologypharmacovigilancepharmacological researchtranslational medicine

Protein Biomarkers Secreted From Human Proximal Tubular Cells Incubated With Nephrotoxic Environmental Chemicals and Drugs: Mitochondrial and Cytoskeletal Proteins (Abstract Id: 166504). Journal of Pharmacology and Experimental Therapeutics (2025)

physiologykidney researchbiomarker targetbiomarkersproteomicscellular physiologyproteome researchclinical proteomicsmitochondrial functionrenal pathophysiologyprotein biomarkersabstract idnephrotoxic environmental chemicalsmolecular physiologycellular biochemistrybiochemistrycell biology

Biomarkers of Exposure in Human Proximal Tubular Cells Incubated With Nephrotoxic Environmental Chemicals and Drugs: Altered Metabolic Pathways. Journal of Pharmacology and Experimental Therapeutics (2024)

Lawrence LashPatricia MathieuXin HuDean P. JonesPaul M. StemmerRita Rosati

public healthphysiologybiomarkerstoxicologybiomarker (medicine)nephrotoxic environmental chemicalscell biology

Mechanisms of Toxicant-Induced Acute Kidney Injury. Elsevier eBooks (2024)

Brian S. Cummings

pharmacologyemergency medicinenephrologytoxicologyrespiratory medicineacute kidney injurycritical care

Renal Glutathione: Dual Roles as Antioxidant Protector and Bioactivation Promoter. Biochemical Pharmacology (2024)

Lawrence H. Lash

bioactivation promoterantioxidant protectorpharmacologyregenerative medicinefree radical biologyredox biologyrenal glutathioneneurosciencebiochemistry

TRICHLOROETHYLENE: An Update on an Environmental Contaminant With Multiple Health Effects. The Annual Review of Pharmacology and Toxicology (2024)

Lawrence H. Lash

environmental toxicologypharmacologyenvironmental contaminanttoxicologymultiple health effects

A Novel Approach to Predicting Organic Anion Transporting Polypeptide Function in Human Hepatic Drug Disposition and Biliary Clearance. Journal of Pharmacology and Experimental Therapeutics (2023)

Lawrence Harold Lash

medicinal chemistrydrug metabolismexperimental pharmacologyclinical pharmacologyliver physiologydrug developmentmedicinepharmacokineticsdrug deliveryhepatologypharmacological researchpharmacologypharmacotherapybiliary clearancedrug discoverytarget predictionorganic anionpolypeptide functionexperimental medicine

Common Pathways in Human Proximal Tubular Cells Altered by Exposures to Diverse Environmental Agents and Nephrotoxic Therapeutic Drugs. Journal of Pharmacology and Experimental Therapeutics (2023)

Lawrence LashPatricia MathieuRita RosatiPaul StemmerXin HuDean P. Jones

nephrotoxic therapeutic drugsnanomedicineshort-term variabilitytoxinstoxicologyenvironmental agentsneurologyenvironmental toxicologyvascular biologykey sitehepatotoxicityhealth sciencesinflammationdermatologytherapeutic targetsregulatory toxicologyrenal functioncommon pathwaysrenal pathophysiologymedicinal researchecotoxicology

Enzymes and Pathways Involved in Processing of Glutathione Conjugates. Elsevier eBooks (2023)

Lawrence H. Lash

gene expressionstructure-function enzyme kineticstranscription (biology)geneticsmolecular metabolismcellular enzymologyprotein synthesismolecular biologycellular biochemistryenzyme catalysisglutathione conjugatesprotein biosynthesisprotein sciencemembrane biologybiochemistry

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Lawrence Lash

Professor of Pharmacology

Wayne State University

Affiliations

Graduate School

School of Medicine

Pharmacology

Lawrence Lash is currently serving as a Graduate School Professor of Pharmacology at Wayne State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Lawrence Lash

Wayne State University

Professor of Pharmacology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

in vitro toxicologyextracellular microvesiclesbiomarkerspharmacologytoxicologytoxicological mechanismpharmacological researchbiochemistrycell biology

A Novel Model System to Predict Efficacy and Safety of Dexamethasone. Journal of Pharmacology and Experimental Therapeutics (2025)

medicinepharmacologypharmacotherapyapplied pharmacologypharmacovigilancepharmacological researchtranslational medicine

Lawrence LashPatricia MathieuXin HuDean P. JonesPaul M. StemmerRita Rosati

public healthphysiologybiomarkerstoxicologybiomarker (medicine)nephrotoxic environmental chemicalscell biology

Mechanisms of Toxicant-Induced Acute Kidney Injury. Elsevier eBooks (2024)

Brian S. Cummings

pharmacologyemergency medicinenephrologytoxicologyrespiratory medicineacute kidney injurycritical care

Renal Glutathione: Dual Roles as Antioxidant Protector and Bioactivation Promoter. Biochemical Pharmacology (2024)

Lawrence H. Lash

bioactivation promoterantioxidant protectorpharmacologyregenerative medicinefree radical biologyredox biologyrenal glutathioneneurosciencebiochemistry

TRICHLOROETHYLENE: An Update on an Environmental Contaminant With Multiple Health Effects. The Annual Review of Pharmacology and Toxicology (2024)

Lawrence H. Lash

environmental toxicologypharmacologyenvironmental contaminanttoxicologymultiple health effects

A Novel Approach to Predicting Organic Anion Transporting Polypeptide Function in Human Hepatic Drug Disposition and Biliary Clearance. Journal of Pharmacology and Experimental Therapeutics (2023)

Lawrence Harold Lash

Common Pathways in Human Proximal Tubular Cells Altered by Exposures to Diverse Environmental Agents and Nephrotoxic Therapeutic Drugs. Journal of Pharmacology and Experimental Therapeutics (2023)

Lawrence LashPatricia MathieuRita RosatiPaul StemmerXin HuDean P. Jones

Enzymes and Pathways Involved in Processing of Glutathione Conjugates. Elsevier eBooks (2023)

Lawrence H. Lash

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Similar Faculty Members

Nathan J Cherrington

Institution

University of Arizona

organic anion transport

toxicology

Rick Schnellmann

Institution

University of Arizona

diabetes therapies

diabetic kidney disease

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Neil Kaplowitz, MD

Institution

University of Southern California

hepatotoxicity

toxicological aspect

Vassilios Papadopoulos

Institution

University of Southern California

steroid metabolism

endocrine mechanism

Xinxin Ding

Institution

University of Arizona

translational research

toxicological aspect

Jeffrey Peters

Institution

Pennsylvania State University

nuclear receptors

toxicological mechanism

Mark Donowitz

Institution

Johns Hopkins University

pharmacology

gastroenterology

Yon Rojanasakul

Institution

West Virginia University

cancer letter

free radical biology

Max Costa

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molecular biology

epigenetics