Faculty

Institution

Unit

Venue

Laszlo Prokai

Professor Pharmacology & Neuroscience ; Member Institute for Healthy Aging

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

University of North Texas Health Science Center

College of Public Health

Graduate School of Biomedical Sciences ; Pharmacology & Neuroscience ; Institute for Healthy Aging

School of Biomedical Sciences

Pharmacology and Neuroscience

Texas College of Osteopathic Medicine

Laszlo Prokai is currently serving as a College Of Biomedical And Translational Sciences Professor Pharmacology & Neuroscience ; Member Institute for Healthy Aging at University of North Texas Health Science Center.

Honors

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Experiences

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Education

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Laszlo Prokai

University of North Texas Health Science Center

Professor Pharmacology & Neuroscience ; Member Institute for Healthy Aging

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pharmacology neuroscience biochemistry mass spectrometry neuropharmacology analytical chemistry endocrinology molecular biology drug delivery medicinal chemistry drug discovery peptides protein science central nervous system protein mass spectrometry peptide science drug analysis pharmaceutical sciences chromatographic analysis redox biology medicinal research proteome research pharmacological research neuroprotection psychoneuroendocrinology neurochemistry analytical atomic spectrometry enzyme inhibition pharmaceutics clinical proteomics drug targeting neuropeptides liquid chromatography controlled release cancer biology biomolecules free radical biology peptide therapeutics tandem mass spectrometry thyrotropin-releasing hormone pharmaceutical chemistry psychopharmacology pharmaceutical research drug development lipid peroxidation chemical measurement neuroendocrine mechanisms hypothalamic peptide proteinlipid interaction cellular neurobiology molecular neurobiology mitochondrial function spectrochemical analysis thyroid hormone gas chromatography environmental analytical chemistry separation science proteomic analysis sequential metabolism peptide engineering neural science analytical instrumentation brain science behavioral neuroendocrinology thyrotropin-releasing hormone analogue sequential bioactivation prodrug design size-exclusion chromatography amino acids tyrosine nitration posttranslational protein carbonylation biological evaluation selective chemoprecipitation rat brain microdialysates phosphonate derivatives methoxime analogs drug delivery systems estrogen receptors artificial membranes protein carbonylation alzheimer disease size exclusion chromatography metabolism antioxidants lipids proteomics gas chromatography-mass spectrometry fourier analysis adrenergic antagonists gel permeation chromatography cyclotron resonance pharmaceutical preparations molecular weight intraocular pressure cell membranes fourier transforms neuroprotective agents oxidative stress chromatography blood-brain barrier neurology hydroxyl radical electrospray ionization

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 7053: Proteomics and Integrative Pathway Analysis to Understand the Mechanism of Action of Mithramycin and Etoposide Combination Induced Cell Death in Ewing Sarcoma Cells. Cancer Research (2025)

cell deathewing sarcoma cellscancer researchmalignant diseasetumor suppressorsetoposide combinationapoptosissarcomaabstract 7053oncogenescancer cellscancer biologypathologytumor biologycell biology

Comprehensive Insights Into Obesity and Type 2 Diabetes From Protein Network, Canonical Pathway, Phosphorylation and Antimicrobial Peptide Signatures of Human Serum. Proteomes (2025)

obesity medicinediabetesinsulin signalingtype 2diabetes researchsystems biologymetabolic syndromemetabolic disordersobesitycomprehensive insightsmetabolic healthhuman serummetabolismhealth sciencesbiochemistry

Estradiol, via Estrogen Receptor β Signaling, Mediates Stress-Susceptibility in the Male Brain. Molecular Psychiatry (2025)

physiologyreproductive endocrinologymale brainendocrinologypineal researchbehavioral neuroendocrinologystress hormoneshormonal receptorpsychoneuroendocrinologystress (biology)neurosciencebehavioral neuroscienceovarian hormones

Retina-Targeted 17β-Estradiol by the Dhed Prodrug Rescues Visual Function and Actuates Neuroprotective Protein Networks After Optic Nerve Crush in a Rat Model of Surgical Menopause. International Journal of Molecular Sciences (2025)

pharmacologyophthalmologyneuro-ophthalmologyretinaoptic nerve crushneuroprotectionsurgical menopausemolecular neurosciencerat modelmolecular neurodegenerationophthalmology retinaneuroscienceneurodegenerative diseases

Direct Sub‐Atmospheric Pressure Ionization Mass Spectrometry: Evaporation/Sublimation ‐Driven Ionization is Amazing, Fundamentally, and Practically. Journal of Mass Spectrometry (2024)

Sarah TrimpinEllen D. InutanVincent S. PagnottiSantosh KarkiDarrell D. MarshallKhoa HoangBeixi WangChristopher B. LietzAlicia L. RichardsFrank S. YenchickChuping LeeI‐Chung LuMadeleine FennerSara MadarshahianSarah SaylorNicolas D. ChubatyiTeresa ZimmermanAbigail Moreno‐PedrazaTongwen WangAdetoun Adeniji‐AdeleAnil K. MeherHasini MadagedaraZachary OwczarzakAhmed MusaviTamara L. HendricksonPatricia M. PeacockJohn W. TomshoBarbara S. LarsenLaszlo ProkaiVladimir ShulaevMilan PophristicCharles N. McEwen

analytical chemistryenvironmental sciencemass spectrometry

Identification of Estrogen-Responsive Proteins in Mouse Seminal Vesicles Through Mass Spectrometry-Based Proteomics. Pharmaceuticals (2024)

proteomicsreproductive endocrinologymass spectrometry-based proteomicsproteome researchreproductive biologyprotein mass spectrometryproteomic technologiesestrogen-responsive proteinsgynecologymouse seminal vesiclescell biology

Identification of Protein Networks and Biological Pathways Driving the Progression of Atherosclerosis in Human Carotid Arteries Through Mass Spectrometry-Based Proteomics. International Journal of Molecular Sciences (2024)

protein networkshuman carotid arteriesproteomicsmass spectrometry-based proteomicsbiomarker discoverycardiovascular researchsystems biologyatherosclerosisproteome researchvascular biologytranslational proteomicsvascular diseaseproteomic technologiesblood vesselsbiochemistryclinical proteomics

Installation of an Indole on the Brca1 Disordered Domain Using Triazine Chemistry. Biomolecules (2024)

Liam E. ClatonChrissy BakerHayes MartinSergei V. DzyubaKhadiza ZamanLaszlo ProkaiMikaela D. StewartEric E. Simanek

triazine chemistryprotein structurebiomolecular engineeringmolecular biologybiomoleculesbiomolecular structurebiochemistry

Neuroprotection by Estrogens. Elsevier eBooks (2024)

Katalin Prokai-TatraiKhadiza ZamanLaszlo Prokai

neurologyendocrinologyneuroscienceneuroprotection

Oral Administration of Ethinyl Estradiol and the Brain-Selective Estrogen Prodrug Dhed in a Female Common Marmoset Model of Menopause: Effects on Cognition, Thermoregulation, and Sleep. Hormones and Behavior (2024)

Emily S RothwellShaun S ViechwegLaszlo ProkaiJessica A MongAgnès Lacreuse

endocrinologypsychologysleepbrain-selective estrogen prodrugmenopause hormone therapyoral administrationpsychoneuroendocrinologyneuroscienceethinyl estradiolbehavioral sciences

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Laszlo Prokai

Professor Pharmacology & Neuroscience ; Member Institute for Healthy Aging

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

University of North Texas Health Science Center

College of Public Health

Graduate School of Biomedical Sciences ; Pharmacology & Neuroscience ; Institute for Healthy Aging

School of Biomedical Sciences

Pharmacology and Neuroscience

Texas College of Osteopathic Medicine

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Laszlo Prokai

University of North Texas Health Science Center

Professor Pharmacology & Neuroscience ; Member Institute for Healthy Aging

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

cell deathewing sarcoma cellscancer researchmalignant diseasetumor suppressorsetoposide combinationapoptosissarcomaabstract 7053oncogenescancer cellscancer biologypathologytumor biologycell biology

Comprehensive Insights Into Obesity and Type 2 Diabetes From Protein Network, Canonical Pathway, Phosphorylation and Antimicrobial Peptide Signatures of Human Serum. Proteomes (2025)

Estradiol, via Estrogen Receptor β Signaling, Mediates Stress-Susceptibility in the Male Brain. Molecular Psychiatry (2025)

Direct Sub‐Atmospheric Pressure Ionization Mass Spectrometry: Evaporation/Sublimation ‐Driven Ionization is Amazing, Fundamentally, and Practically. Journal of Mass Spectrometry (2024)

analytical chemistryenvironmental sciencemass spectrometry

Identification of Estrogen-Responsive Proteins in Mouse Seminal Vesicles Through Mass Spectrometry-Based Proteomics. Pharmaceuticals (2024)

Installation of an Indole on the Brca1 Disordered Domain Using Triazine Chemistry. Biomolecules (2024)

Liam E. ClatonChrissy BakerHayes MartinSergei V. DzyubaKhadiza ZamanLaszlo ProkaiMikaela D. StewartEric E. Simanek

triazine chemistryprotein structurebiomolecular engineeringmolecular biologybiomoleculesbiomolecular structurebiochemistry

Neuroprotection by Estrogens. Elsevier eBooks (2024)

Katalin Prokai-TatraiKhadiza ZamanLaszlo Prokai

neurologyendocrinologyneuroscienceneuroprotection

Emily S RothwellShaun S ViechwegLaszlo ProkaiJessica A MongAgnès Lacreuse

endocrinologypsychologysleepbrain-selective estrogen prodrugmenopause hormone therapyoral administrationpsychoneuroendocrinologyneuroscienceethinyl estradiolbehavioral sciences

1
2
3
4
5
25
10 / page