Faculty

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Kumar B. Rajan

Rush University

Affiliations

College of Nursing

Department Of Women, Children And Family Nursing

Rush Institute For Healthy Aging

Kumar B. Rajan is a Senior Professor at Rush University, specializing in the neuroscience of aging, dementia, and public health. His research focuses on the epidemiological determinants of cognitive decline and Alzheimer's disease, particularly the impacts of socioeconomic status, social isolation, and cardiovascular health. His recent 2025 publications in journals such as *JAMA Network Open* and *Neurology* explore the interplay of *APOE4*, blood neurodegenerative biomarkers, and lifestyle factors on brain aging. His work also addresses methodological challenges in cognitive aging research through coordinated multi-cohort analyses.

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Kumar B. Rajan

Rush University

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health sciences public health geriatrics dementia cognitive decline alzheimer's disease neurology epidemiology neuroscience of aging cognitive impairment ageing older adults later adulthood mental health experimental gerontology social gerontology aging-associated diseases human genetics geriatric medicine cohort studies population health clinical gerontology cognitive function biogerontology healthy lifestyle biracial population sample human nutrition community-dwelling older adults psychological medicine respiratory medicine population aging healthy aging loneliness racial differences depressive symptoms elderly care nutritional sciences chicago health population sample vascular dementia vascular cognitive disorder retrospective cohort studies dietary health united states medicinal research biological psychiatry genome biology clinical nutrition public health nutrition molecular neurodegeneration psychiatric research epidemiologic research clinical neurology neuropsychiatry population studies clinical evidence community health human variation human cognition incident stroke alzheimer disease cognitive performance applied cognitive psychology developmental psychology neuropsychopharmacology cerebral blood flow cardiovascular research genetic predisposition psychosocial research cognitive psychology endocrine research blood pressure allelic variant psychiatric genetics mild cognitive impairment alzheimer disease dementia

Notable Scholarly Works

Notable Federal Grants

Collaborators

Apolipoprotein E ε4-Dependent Associations Between Carotenoids and Cognitive Decline: Findings From the Mind (Mediterranean-Dash Intervention for Neurodegenerative Delay) Randomized Controlled Trial. American Journal of Clinical Nutrition (2025)

mind randomizedbrain healthcognitive impairmentneuroscience of agingneurodegenerative diseasesaging-associated diseasesneurosciencecognitive declineneuropsychologypsychoneuroendocrinologyphysiologyapoe-ε4-dependent associationscognitive science

Approaches to Timescale Choice in Cognitive Aging Research and Potential Implications for Estimated Exposure Effects: Coordinated Analyses in 10 Cohorts of Older Adults. Epidemiology (2025)

Eleanor Hayes-LarsonRyan M. AndrewsKatrina L. KeziosAriane BercuAnaïs RouanetCatherine HelmerPaul K. CraneLaura GibbonsBrandon S. KlinedinstLinda K. McEvoyEmma NicholsJennifer WeuveKumar B. RajanPhillip H. HwangJesse MezMateo FarinaCrystal ShawKendra D. SimsTerry TherneauRonald C PetersenVincent BouteloupAlden GrossMarilyn AlbertJohn C. MorrisColin L. MastersSusan M. ResnickPaul MaruffJennifer J. ManlyIndira TurneyJet M.J. VonkJustina Avila-RiegerAlexandra WeigandRuijia ChenJingxuan WangCécile Proust-LimaElizabeth Rose Mayeda

potential implicationscohort studieslongitudinal studiesten cohortsolder adultsexposure effectsepidemiology

Association of Tailpipe-Related and Nontailpipe-Related Air Pollution Exposure With Neuroimaging Outcomes. Environmental Epidemiology (2025)

environmental healthinhalation toxicologyenvironmental exposuresenvironmental health perspectiveneuroscienceair qualityenvironmental epidemiologyair pollutionhuman exposureneuroimaging outcomes

Author Response: Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults. Neurology (2025)

incident alzheimer diseasestatin initiationcognitive impairmentclinical lipidologyneuroscience of agingalzheimer's diseaseneurodegenerative diseasesaging-associated diseasesvascular dementiaauthor responseageingneurologyhealth sciencesepidemiology

Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults. JAMA Network Open (2025)

cerebral blood flowneuroscience of agingneurodegenerative diseasesalzheimer's diseaseneurochemical biomarkersaging-associated diseasesvascular dementianeuroscienceolder adultsvascular cognitive disordermolecular neurodegenerationcardiovascular researchneurologyhealth sciences

Cognitive Activity From Early to Late Life and the Risk of Ad Dementia. Neurology Open Access (2025)

Klodian DhanaRobert S. WilsonTodd BeckDenis A. EvansKumar B. Rajan

ad dementiacognitive impairmentneuroscience of agingneurodegenerative diseasescognitive activitydementiaearly life exposureslate lifecognitive science

Development and Validation of a Harmonized Memory Score for Multicenter Alzheimer’s Disease and Related Dementia Research. medRxiv (2025)

Mark Sanderson-CiminoAlden L. GrossLeslie S. GaynorEmily W. PaolilloRowan SalonerMarilyn S. AlbertLiana G. ApostolovaBrooke BoersemaAdam L. BoxerBrad F. BoeveKaitlin B. CasalettoSavannah R HallgarthValentina E DiazLindsay R. ClarkPauline MaillardAni EloyanSarah Tomaszewski FariasMitzi M. GonzalesDustin B. HammersRenaud La JoieYann CobigoAmy WolfBenjamin M. HampsteadDawn Mechanic-HamiltonBruce L. MillerGil D. RabinoviciJohn M. RingmanHowie J. RosenSephira G. RymanJillian L. PrestopnikDavid P. SalmonGlenn E. SmithCharles DeCarliKumar B. RajanLee-Way JinJason HinmanDavid K. JohnsonDanielle HarveyMyriam FornageJoel H. KramerAdam M Staffaroni

memory losscognitive impairmentmemoryalzheimer's diseaseneurodegenerative diseasesdementianeuroscience of agingrelated dementia researchneurosciencememory assessmentharmonized memory scoremulticenter alzheimercognitive sciencedegenerative diseaseneurology

Dietary Fat Intake, Blood Tau Levels, and Cognitive Decline in Older Adults. Alzheimer s & Dementia (2025)

cognitive impairmentneuroscience of agingaging-associated diseasesgeriatric endocrinologynutritionageingblood tau levelscognitive declinedietary fat intakepublic healthhealth sciencesexperimental gerontologyhealthy aging

Effect of Weight Loss Through Dietary Interventions on Cardiometabolic Health in Older Adults. International Journal of Obesity (2025)

obesity managementpublic health nutritionnutritionlifestyle modificationcardiometabolic healthweight lossolder adultsobesitypublic healthhealth sciencesdietary healthmetabolic syndromehealth promotion

Apoe4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults. JAMA Network Open (2025)

cognitive impairmentneuroscience of agingneurodegenerative diseasesneurochemical biomarkersdementiaaging-associated diseasesvascular dementiablood neurodegenerative biomarkerscommunity-dwelling older adultsageingneurosciencecognitive declinevascular cognitive disordermolecular neurodegenerationneurology

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Kumar B. Rajan

Rush University

Affiliations

College of Nursing

Department Of Women, Children And Family Nursing

Rush Institute For Healthy Aging

Honors

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Experiences

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Education

Create free account to unlock more features

Kumar B. Rajan

Rush University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Approaches to Timescale Choice in Cognitive Aging Research and Potential Implications for Estimated Exposure Effects: Coordinated Analyses in 10 Cohorts of Older Adults. Epidemiology (2025)

potential implicationscohort studieslongitudinal studiesten cohortsolder adultsexposure effectsepidemiology

Association of Tailpipe-Related and Nontailpipe-Related Air Pollution Exposure With Neuroimaging Outcomes. Environmental Epidemiology (2025)

environmental healthinhalation toxicologyenvironmental exposuresenvironmental health perspectiveneuroscienceair qualityenvironmental epidemiologyair pollutionhuman exposureneuroimaging outcomes

Author Response: Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults. Neurology (2025)

Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults. JAMA Network Open (2025)

Cognitive Activity From Early to Late Life and the Risk of Ad Dementia. Neurology Open Access (2025)

Klodian DhanaRobert S. WilsonTodd BeckDenis A. EvansKumar B. Rajan

ad dementiacognitive impairmentneuroscience of agingneurodegenerative diseasescognitive activitydementiaearly life exposureslate lifecognitive science

Development and Validation of a Harmonized Memory Score for Multicenter Alzheimer’s Disease and Related Dementia Research. medRxiv (2025)

Dietary Fat Intake, Blood Tau Levels, and Cognitive Decline in Older Adults. Alzheimer s & Dementia (2025)

Effect of Weight Loss Through Dietary Interventions on Cardiometabolic Health in Older Adults. International Journal of Obesity (2025)

Apoe4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults. JAMA Network Open (2025)

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