Faculty

Institution

Unit

Venue

Keith Gooch

Professor

Ohio State University

Affiliations

College of Engineering

Biomedical Engineering

Keith Gooch is currently serving as a Biomedical Engineering Professor at Ohio State University.

Honors

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Experiences

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Education

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Keith Gooch

Ohio State University

Professor

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biomedical engineering tissue engineering vascular biology regenerative medicine biomechanics biophysics cell biology cardiology biological engineering cell biomechanics angiology membrane biology angiogenesis structural biology biomechanical engineering matrix biology cellular physiology liver physiology nanotechnology applied physiology mechanical science circulatory physiology orthopedic biomechanics tissue physiology cardiovascular physiology spinal biomechanics ex vivo cartilage redox biology bone research cell-matrix interactions material research mammalian biology fibers nanobiotechnology tissue transplantation biomaterials design cell culture arterial disease cellular biology human physiology substrate stiffness tissue-engineered microvascular networks transmural pressure additive manufacturing free radical biology cell research cell physiology tissue development vascular adaptation micro technology biocompatible materials 3d bioprinting gene delivery biomedical modeling mechanical modeling biomedical technologies cell interactions growth factors tissue-engineered cartilage endothelial stiffness network formation mechanical forces porcine saphenous veins human saphenous veins intimal hyperplasia experimental biophysics tumor targeting therapeutic nanomaterials clinical gastroenterology oncogenic agent gastrointestinal oncology endothelial force generation cell stiffness endothelial actin differential effects bioengineering model

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Mechanistic Motor-Clutch Model That Explains Cell Shape Dynamics to Cyclic Stretch. Molecular Biology of the Cell (2022)

Benjamin W. ScandlingJia GouJessica ThomasJacqueline XuanChuan XueKeith J. Gooch

biophysicsmechanicscell biomechanicsmolecular biologycell shape dynamicsmechanistic motor-clutch modelstructural biologybiomechanicscell biology

Click Chemistry Functionalization of Self‐Assembling Peptide Hydrogels. Journal of Biomedical Materials Research Part A (2022)

Joe T. SharickAngelina J. AtiehKeith J. GoochJennifer L. Leight

materials sciencebiomedical engineeringclick chemistry functionalizationclick chemistrybiomaterialsadvanced materialspolymer science

Decreased Substrate Stiffness Promotes a Hypofibrotic Phenotype in Cardiac Fibroblasts. International Journal of Molecular Sciences (2021)

Rachel C. ChildersPamela A. LucchesiKeith J. Gooch

cardiac fibroblastsmechanobiologymembrane sciencesurface reactivitysubstrate stiffnesssingle molecule biophysicsmolecular sciencestructural biologyprotein sciencemembrane biologycardiologymammalian biologyhypofibrotic phenotypefragmentation effectstructural integritybiophysicsgeneticsmolecular biologystructural molecular biologynovel interfacemolecular medicine

Paired Pressure–Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts. Journal of Biomechanical Engineering (2021)

Rachel C. ChildersAaron J. TraskJun LiuPamela A. LucchesiKeith J. Gooch

cardiologybiomechanical engineeringspinal biomechanicsbiophysicscardiovascular physiologyvolume overloadbiomedical engineeringmechanical engineeringdeformationorthopedic biomechanicscell biomechanicsfluid mechanicspressure-volume loop analysisbiomechanicsmechanical science

Abstract 844: Β IV -Spectrin Regulates Cardiac Fibroblast Phenotype, Fibrosis, and Cardiac Function. Circulation Research (2019)

Nehal J PatelDrew M NassalBenjamin W ScandlingAmara D Greer-ShortSathya D UnudurthiXianyao XuPeter J MohlerKeith J GoochThomas J Hund

physiologycardiologycardiovascular functionfibrosiscardiovascular researchcardiac fibroblast phenotypegeneticstissue physiologymembrane biologycardiac functioncirculatory physiologyhealth sciences

ΒIv-Spectrin/Stat3 Complex Regulates Fibroblast Phenotype, Fibrosis, and Cardiac Function. JCI Insight (2019)

Nehal J. PatelDrew M. NassalAmara D. Greer-ShortSathya D. UnudurthiBenjamin W. ScandlingDaniel GratzXianyao XuAnuradha KalyanasundaramVadim V. FedorovFederica AccorneroPeter J. MohlerKeith J. GoochThomas J. Hund

immunologycardiovascular functionfibrosishematologyfibroblast phenotypegeneticsstatisticscardiac function

Independent Control of Matrix Adhesiveness and Stiffness Within a 3D Self-Assembling Peptide Hydrogel. Acta Biomaterialia (2018)

Nathaniel J. HogrebeJames W. ReinhardtNguyen K. TramAnna C. DebskiGunjan AgarwalMatthew A. ReillyKeith J. Gooch

materials sciencematrix adhesivenessbiomaterial modelingbiomedical engineeringmechanical engineeringself-assembling peptide hydrogelself-assemblybiomaterials designcomposite sciencebiomaterials3d bioprintingindependent controlpolymer sciencebiomechanics3d printingadditive manufacturingpolymer self-assembly

Labeling of Endothelial Cells With Magnetic Microbeads by Angiophagy. Author eBooks (2018)

Jessica ThomasDesiree JonesLeni MoldovanMirela AnghelinaKeith J. GoochNicanor I. Moldovan

dermatologyvascular biologytissue engineeringmagnetic microbeadsendothelial cellsdevelopmental biologymembrane biologycell biology

Role of the Cytoskeleton in the Development of a Hypofibrotic Cardiac Fibroblast Phenotype in Volume Overload Heart Failure. AJP Heart and Circulatory Physiology (2018)

Rachel C. ChildersIan SunyeczT. Aaron WestMary J. CismowskiPamela A. LucchesiKeith J. Gooch

physiologycardiologyheart failurecardiovascular physiologyelectrophysiologycellular physiologycytoskeletonapplied physiologycardiovascular researchhuman physiologydevelopmental biologycirculatory physiologyneurophysiologycell biology

An Agent-Based Discrete Collagen Fiber Network Model of Dynamic Traction Force-Induced Remodeling. Journal of Biomechanical Engineering (2017)

James W. ReinhardtKeith J. Gooch

biomechanical engineeringbiomedical modelingbiomedical engineeringmechanical engineeringmechanical propertiesapplied physiologyorthopedic biomechanicstissue engineeringrehabilitation engineeringbone researchmatrix biologycell biomechanicsmechanical modelingfiber sciencebiomechanicsbiological engineeringmechanical sciencefibers

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Keith Gooch

Professor

Ohio State University

Affiliations

College of Engineering

Biomedical Engineering

Keith Gooch is currently serving as a Biomedical Engineering Professor at Ohio State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Keith Gooch

Ohio State University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Mechanistic Motor-Clutch Model That Explains Cell Shape Dynamics to Cyclic Stretch. Molecular Biology of the Cell (2022)

Benjamin W. ScandlingJia GouJessica ThomasJacqueline XuanChuan XueKeith J. Gooch

biophysicsmechanicscell biomechanicsmolecular biologycell shape dynamicsmechanistic motor-clutch modelstructural biologybiomechanicscell biology

Click Chemistry Functionalization of Self‐Assembling Peptide Hydrogels. Journal of Biomedical Materials Research Part A (2022)

Joe T. SharickAngelina J. AtiehKeith J. GoochJennifer L. Leight

materials sciencebiomedical engineeringclick chemistry functionalizationclick chemistrybiomaterialsadvanced materialspolymer science

Decreased Substrate Stiffness Promotes a Hypofibrotic Phenotype in Cardiac Fibroblasts. International Journal of Molecular Sciences (2021)

Rachel C. ChildersPamela A. LucchesiKeith J. Gooch

Rachel C. ChildersAaron J. TraskJun LiuPamela A. LucchesiKeith J. Gooch

Abstract 844: Β IV -Spectrin Regulates Cardiac Fibroblast Phenotype, Fibrosis, and Cardiac Function. Circulation Research (2019)

Nehal J PatelDrew M NassalBenjamin W ScandlingAmara D Greer-ShortSathya D UnudurthiXianyao XuPeter J MohlerKeith J GoochThomas J Hund

physiologycardiologycardiovascular functionfibrosiscardiovascular researchcardiac fibroblast phenotypegeneticstissue physiologymembrane biologycardiac functioncirculatory physiologyhealth sciences

ΒIv-Spectrin/Stat3 Complex Regulates Fibroblast Phenotype, Fibrosis, and Cardiac Function. JCI Insight (2019)

immunologycardiovascular functionfibrosishematologyfibroblast phenotypegeneticsstatisticscardiac function

Independent Control of Matrix Adhesiveness and Stiffness Within a 3D Self-Assembling Peptide Hydrogel. Acta Biomaterialia (2018)

Nathaniel J. HogrebeJames W. ReinhardtNguyen K. TramAnna C. DebskiGunjan AgarwalMatthew A. ReillyKeith J. Gooch

Labeling of Endothelial Cells With Magnetic Microbeads by Angiophagy. Author eBooks (2018)

Jessica ThomasDesiree JonesLeni MoldovanMirela AnghelinaKeith J. GoochNicanor I. Moldovan

dermatologyvascular biologytissue engineeringmagnetic microbeadsendothelial cellsdevelopmental biologymembrane biologycell biology

Role of the Cytoskeleton in the Development of a Hypofibrotic Cardiac Fibroblast Phenotype in Volume Overload Heart Failure. AJP Heart and Circulatory Physiology (2018)

Rachel C. ChildersIan SunyeczT. Aaron WestMary J. CismowskiPamela A. LucchesiKeith J. Gooch

An Agent-Based Discrete Collagen Fiber Network Model of Dynamic Traction Force-Induced Remodeling. Journal of Biomechanical Engineering (2017)

James W. ReinhardtKeith J. Gooch

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