Faculty

Institution

Unit

Venue

Kate E. Keller

Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Ophthalmology

Institute Of Casey Eye

Oregon Health & Science University

Kate E. Keller is currently serving as an Ophthalmology Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences at Oregon Health & Science University.

Honors

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Experiences

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Education

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Kate E. Keller

Oregon Health & Science University

Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences

You can click a keyword to filter the displayed items

ophthalmology trabecular meshwork extracellular matrix cell biology glaucoma matrix biology cellular physiology biomedical engineering tissue (biology) mechanobiology ocular surface cell-matrix interactions trabecular meshwork cells cell biomechanics visual science cell adhesion biomechanics ophthalmology retina molecular cell biology ocular tissues tissue engineering ocular disease experimental ophthalmology cell signaling cell research outflow facility molecular biology vision research ocular surface physiology ocular pathology retina biomedical research hypertension mechanical science circulatory physiology vascular biology biofabrication stem cell research biophysical review eye health aqueous humour human tissues tissue physiology intraocular pressure regulation extracellular matrix turnover human trabecular meshwork orthopaedic research craniofacial research hearing research anatomical model blood pressure adult stem cells key site nanobiotechnology nanonetworks soft tissue reconstruction protein function cell regulation mechanical behavior structural plasticity tissue development genetic disorders disease gene identification medical genetics clinical medicine elastic modulus determination outflow resistance intraocular pressure homeostasis glaucomatous outflow regulation segmental versican expression segmental outflow pathways molecular differences mechanical stretching unique extracellular matrix ocular trabecular meshwork juxtacanalicular region pathology biomedical analysis dermatology developmental biology confocal microscopy cell and molecular biology optogenetics vision rehabilitation wound healing nature translational research biophotonics biological imaging scleroderma biological engineering medical optical imaging photomedicine developmental cell translational medicine neuro-ophthalmology laboratory investigation science advance in vitro toxicology regeneration (biology) biophysics regenerative medicine nature method cell engineering cytoskeleton histopathology experimental medicine biomolecular engineering cosmetic dermatology

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Switch From α5β1 to αVβ3 Integrin Activity Contributes to the Development of a Profibrotic Mesenchymal Phenotype in Trabecular Meshwork Cells. Frontiers in Cell and Developmental Biology (2026)

developmental biologycytoskeletoncell biologycell signalingmechanobiologyintegrin activitycell-matrix interactionsextracellular matrixcell researchmatrix biologymechanotransductioncell adhesiontrabecular meshwork cellscellular physiologyprofibrotic mesenchymal phenotype

Effects of Ascorbic Acid on Trabecular Meshwork Gene Expression and Collagen Secretion. BMJ Open Ophthalmology (2026)

Isobaric Quantitative Proteomics Reveals Altered Extracellular Matrix, Cytoskeletal, and Degradation Pathways in Glaucomatous Trabecular Meshwork Cells. Scientific Reports (2026)

developmental biologycell biomechanicsage-related dysregulationmolecular cell biologycell biologycell signalingmechanobiologycell-matrix interactionsmatrix biologymechanotransductioncell adhesiontrabecular meshwork cellscellular physiology

Fibrosis-Related Gene and Protein Expression in Normal and Glaucomatous Trabecular Meshwork Cells. Investigative Ophthalmology & Visual Science (2025)

trabecular meshworkocular tissuesfibrosisfibrosis-related genecell biologyglaucomaocular surface physiologymatrix biologytissue (biology)ophthalmologyprotein expressionocular surface

Tubulin Acetylation Enhances Microtubule Stability in Trabecular Meshwork Cells Under Mechanical Stress. Investigative Ophthalmology & Visual Science (2025)

Chien-Chia SuVaibhav DesikanKevin BetschMyoung Sup ShimKate E. KellerPaloma B. Liton

cell biomechanicstrabecular meshworkvisual sciencemechanobiologytubulin acetylationophthalmologymicrotubule stabilitymechanical stresstrabecular meshwork cellsbiomechanics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

Ted S. AcottMichael P. FautschWeiming MaoC. Ross EthierAlex S. HuangMary J. KelleyMini AgaSanjoy K. BhattacharyaTerete BorrasDiane BovenkampUttio Roy ChowdhuryAbbot F. ClarkMohammed I. DibasYiqin DuMichael H. ElliottJennifer A. FaralliHaiyan GongSamuel HerbergMurray A. JohnstonePaul L. KaufmanKate E. KellerRuth A. KellyDavid KrizajMarkus H. KuehnHoi Lam LiRaquel LiebermanShan C. LinYutao LiuFiona S. McDonnellColleen M. McDowellGillian J. McLellanPhilip MzykKayarat Saidas NairDarryl R. OverbyDonna M. PetersVijayKrishna RaghunathanPonugoti Vasantha RaoGavin W. RoddyNajam A. SharifMyoung Sup ShimYang SunBenjamin R. ThomsonCarol B. TorisColin E. WilloughbyHao F. ZhangThomas F. FreddoRudolf FuchshoferKamisha R. HillAlireza KarimiKrishnakumar KizhatilCasey C. KopcyznskiPaloma LitonGaurang PatelMichael PengPadmanabhan P. PattabiramanGanesh PrasannaEster Reina-TorresE. Griffen SamplesJohn R. SamplesCynthia L. SteelClemens A. StrohmaierPreeti SubramanianChenna Kesavulu SugaliJoseph van Batenburg-SherwoodCydney WongHannah YoungbloodGulab S. ZodeElizabeth WhiteW. Daniel Stamer

visual scienceocular tissuesintraocular pressure regulationvision researchocular surface physiologyophthalmologyoutflow facilityexperimental ophthalmologyocular surfacemedical optical imaging

Consensus Recommendations for Trabecular Meshwork Cell Isolation, Characterization and Culture. UNC Libraries (2024)

tissue engineeringcell manipulationcell cultureconsensus recommendationsbiological engineeringtissue culturebiomedical engineeringmatrix biologycell researchtissue (biology)

Digital Spatial Profiling of Segmental Outflow Regions in Trabecular Meshwork Reveals a Role for Adam15. PLoS ONE (2024)

Jennifer A. FaralliMark S. FillaYong-Feng YangYing Ying SunKassidy JohnsKate E. KellerDonna M. Peters

trabecular meshworkcell biologydigital spatial profilingmaterials sciencesegmental outflow regionshealth sciencesstructural biology

Nanotubules and Cellular Communication in Trabecular Meshwork Cells. Methods in molecular biology (2024)

biophysicscell biomechanicscytoskeletonbiomedical engineeringmatrix biologytrabecular meshwork cellscellular physiology

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Kate E. Keller

Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Ophthalmology

Institute Of Casey Eye

Oregon Health & Science University

Kate E. Keller is currently serving as an Ophthalmology Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Kate E. Keller

Oregon Health & Science University

Professor of Ophthalmology Graduate Faculty Program in Molecular and Cellular Biosciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Effects of Ascorbic Acid on Trabecular Meshwork Gene Expression and Collagen Secretion. BMJ Open Ophthalmology (2026)

Isobaric Quantitative Proteomics Reveals Altered Extracellular Matrix, Cytoskeletal, and Degradation Pathways in Glaucomatous Trabecular Meshwork Cells. Scientific Reports (2026)

Fibrosis-Related Gene and Protein Expression in Normal and Glaucomatous Trabecular Meshwork Cells. Investigative Ophthalmology & Visual Science (2025)

trabecular meshworkocular tissuesfibrosisfibrosis-related genecell biologyglaucomaocular surface physiologymatrix biologytissue (biology)ophthalmologyprotein expressionocular surface

Tubulin Acetylation Enhances Microtubule Stability in Trabecular Meshwork Cells Under Mechanical Stress. Investigative Ophthalmology & Visual Science (2025)

Chien-Chia SuVaibhav DesikanKevin BetschMyoung Sup ShimKate E. KellerPaloma B. Liton

cell biomechanicstrabecular meshworkvisual sciencemechanobiologytubulin acetylationophthalmologymicrotubule stabilitymechanical stresstrabecular meshwork cellsbiomechanics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

visual scienceocular tissuesintraocular pressure regulationvision researchocular surface physiologyophthalmologyoutflow facilityexperimental ophthalmologyocular surfacemedical optical imaging

Consensus Recommendations for Trabecular Meshwork Cell Isolation, Characterization and Culture. UNC Libraries (2024)

tissue engineeringcell manipulationcell cultureconsensus recommendationsbiological engineeringtissue culturebiomedical engineeringmatrix biologycell researchtissue (biology)

Digital Spatial Profiling of Segmental Outflow Regions in Trabecular Meshwork Reveals a Role for Adam15. PLoS ONE (2024)

Jennifer A. FaralliMark S. FillaYong-Feng YangYing Ying SunKassidy JohnsKate E. KellerDonna M. Peters

trabecular meshworkcell biologydigital spatial profilingmaterials sciencesegmental outflow regionshealth sciencesstructural biology

Nanotubules and Cellular Communication in Trabecular Meshwork Cells. Methods in molecular biology (2024)

biophysicscell biomechanicscytoskeletonbiomedical engineeringmatrix biologytrabecular meshwork cellscellular physiology

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10 / page