Faculty

Institution

Unit

Venue

Karen M. Henkels

Wright State University

Affiliations

Boonshoft School of Medicine

Biochemistry and Molecular Biology

College of Science and Mathematics

Biochemistry and Molecular Biology

NoneKaren M. Henkels is currently serving as a Biochemistry And Molecular Biology faculty at Wright State University.

Honors

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Experiences

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Education

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Karen M. Henkels

Wright State University

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molecular biology cell biology biochemistry membrane biology pharmacology cell signaling protein science enzymes tumor biology gene expression structural biology enzyme inhibition medicinal research cellular physiology signal transduction biological chemistry molecular cell biology oncology cellular therapy cancer biology molecular physiology mammalian biology cellular biology biological inorganic chemistry molecular regulation cell death leukemia redox biology cellular biochemistry biochemical sciences cancer treatment cancer genomics cancer genetics cell migration signaling pathways protein phosphorylation rna biology protein function protein transport cisplatin-damaged dna phosphatidic acid gynecologic oncology cancer cells apoptosis catalyst activation biomolecular interactions oncogenic agent cell regulation cell physiology cell invasion lipid chemistry lipid science lipoprotein metabolism biomedical research cancer risk cancer growth adaptive immune system innate immune system transcription regulation cell interactions proteinlipid interaction enzyme specificity tumor suppressors tumor growth human ku autoantigen aurora kinase non-mitotic role two-step mechanism ldl phagocytosis foam cell formation leukocyte chemoattractant intracellular localization lipase activity comprehensive model leukocyte responses neutrophils infiltration

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Reply to Peer Reviews of Myotubularin-Related Proteins Regulate Kras Function by Controlling Plasma Membrane Levels of Polyphosphoinositides and Phosphatidylserine. (2024)

Karen HenkelsTaylor MillerAli NajiRansome van der HoevenHong LiangYong ZhouGerald R HammondJohn F. HancockKwang-Jin Cho

neurologymembrane biologyplasma membrane levelskras functionneurosciencemyotubularin-related proteinsphysiology

Evidence for the Involvement of Keratinocyte‐Derived Microvesicle Particles in the Photosensitivity Associated With Xeroderma Pigmentosum Type a Deficiency. Photochemistry and Photobiology (2024)

Lea ChristianPranali ManjrekarKaren M. HenkelsChristine M. RappRisha AnnamrajuRushabh P. LohadeShikshita SinghM. Alexandra CarpenterSaman KhanMichael G. KempYanfang ChenRavi P. SahuJeffrey B. Travers

ophthalmologykeratinocyte-derived microvesicle particlesimmunologydermatologyphotochemistryphotobiology

Evidence That Keratinocyte Microvesicle Particles Carrying Platelet-Activating Factor Mediate the Widespread Multiorgan Damage Associated With Intoxicated Thermal Burn Injury. Journal of Leukocyte Biology (2024)

Rushabh P LohadeChad BrewerChristine M RappKaren M HenkelsWenfeng ZhangAnita ThyagarajanShikshita SinghPranali ManjrekarTaskin SabitRavi P SahuJeffrey B Travers

cellular physiologythermal protectionimmune responseshematologyregenerative medicinecutaneous biologytumor biologythermal therapiesdermatologystem cell toxicologyvascular biologycell deathinflammationtissue injuryimmunologyplatelet-activating factorstem cell researchepidemiologykeratinocyte microvesicle particlesmedicinal research

Exposure to Benzo[a]Pyrene Augments Ultraviolet B Radiation-Induced Systemic Immunosuppression in a Platelet-Activating Factor-Receptor Dependent Manner. Journal of Pharmacology and Experimental Therapeutics (2024)

Anita ThyagarajanLangni LiuChristine M. RappKaren M. HenkelsJeffrey B. TraversRavi P. Sahu

inflammationradiation oncologyexposure assessmentradiationimmunosuppressionhuman exposureimmunologydermatologyradiation biologyradiation exposure

Intoxicated Thermal Burn Injury‐Mediated Systemic Immunosuppression Involves Platelet‐Activating Factor and Microvesicle Particles. Skin Research and Technology (2024)

Rushabh P. LohadeChristine M. RappKaren M. HenkelsJeffrey B. Travers

inflammationfragmentation effectliver physiologymicrovesicle particlescutaneous biologyimmunosuppressionhemostasistissue injuryimmunologydermatologyvascular biologytissue engineeringbone researchnephrologyplatelet-activating factorregenerative medicinewound healingepidemiology

Karen M. HenkelsTaylor E. MillerAli NajiRansome van der HoevenHong LiangYong ZhouGerald R.V. HammondJohn F. HancockKwang-jin Cho

hepatologymembrane biologyplasma membrane levelsbiophysicsliver physiologykras functionneurosciencecellular physiologyprotein functionmyotubularin-related proteinsvascular biologyprotein scienceprotein transportmolecular regulationphysiology

Radiation Therapy Generates Release of Microvesicle Particles in Keratinocytes. International Journal of Radiation Oncology*Biology*Physics (2023)

E.J.V. TorralbaS. SinghW.R. RuckK. HenkelsC. RappJ.B. TraversR. Short

microvesicle particlesradiation oncologyradiationradiation therapydermatology

Radiation Therapy Produces Microvesicle Particle Release in Hacat Keratinocytes. Skin Research and Technology (2023)

Ericson John V. TorralbaShikshita SinghRobert F. ShortChristine M. RappKaren M. HenkelsRavi P. SahuJeffrey B. Travers

microvesicle particle releaseradiation oncologyradiationradiation therapyradiation biologydermatologyhacat keratinocytescell biology

Blocking K-Ras Interaction With the Plasma Membrane is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity. Frontiers in Molecular Biosciences (2021)

Karen M. HenkelsKristen M. RehlKwang-jin Cho

tumor targetingplasma membranegene therapyanti-cancer agentsk-ras interactionmolecular cancerbiological therapiesmolecular medicinetumor biologyanticoagulantscell deathneurologypharmacologyoncogenic k-ras activityoncogenic agentinflammationcellular therapyenzyme inhibitionradiation oncologymedicinal researchtherapeutic targets

Avicin G is a Potent Sphingomyelinase Inhibitor and Blocks Oncogenic K- and H-Ras Signaling. Scientific Reports (2020)

Christian M. GarridoKaren M. HenkelsKristen M. RehlHong LiangYong ZhouJordan U. GuttermanKwang-jin Cho

neurologypharmacologyreceptorsavian biologygene expressionh-ras signalingcancer researchhost factorsenzyme inhibitionmolecular biologycell signalingtumor biologymedicinal researchfunctional regulationvascular biologyprotein sciencein vivo systems

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Karen M. Henkels

Wright State University

Affiliations

Boonshoft School of Medicine

Biochemistry and Molecular Biology

College of Science and Mathematics

Biochemistry and Molecular Biology

NoneKaren M. Henkels is currently serving as a Biochemistry And Molecular Biology faculty at Wright State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Karen M. Henkels

Wright State University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Reply to Peer Reviews of Myotubularin-Related Proteins Regulate Kras Function by Controlling Plasma Membrane Levels of Polyphosphoinositides and Phosphatidylserine. (2024)

Karen HenkelsTaylor MillerAli NajiRansome van der HoevenHong LiangYong ZhouGerald R HammondJohn F. HancockKwang-Jin Cho

neurologymembrane biologyplasma membrane levelskras functionneurosciencemyotubularin-related proteinsphysiology

Evidence for the Involvement of Keratinocyte‐Derived Microvesicle Particles in the Photosensitivity Associated With Xeroderma Pigmentosum Type a Deficiency. Photochemistry and Photobiology (2024)

Lea ChristianPranali ManjrekarKaren M. HenkelsChristine M. RappRisha AnnamrajuRushabh P. LohadeShikshita SinghM. Alexandra CarpenterSaman KhanMichael G. KempYanfang ChenRavi P. SahuJeffrey B. Travers

ophthalmologykeratinocyte-derived microvesicle particlesimmunologydermatologyphotochemistryphotobiology

Rushabh P LohadeChad BrewerChristine M RappKaren M HenkelsWenfeng ZhangAnita ThyagarajanShikshita SinghPranali ManjrekarTaskin SabitRavi P SahuJeffrey B Travers

Anita ThyagarajanLangni LiuChristine M. RappKaren M. HenkelsJeffrey B. TraversRavi P. Sahu

inflammationradiation oncologyexposure assessmentradiationimmunosuppressionhuman exposureimmunologydermatologyradiation biologyradiation exposure

Intoxicated Thermal Burn Injury‐Mediated Systemic Immunosuppression Involves Platelet‐Activating Factor and Microvesicle Particles. Skin Research and Technology (2024)

Rushabh P. LohadeChristine M. RappKaren M. HenkelsJeffrey B. Travers

Karen M. HenkelsTaylor E. MillerAli NajiRansome van der HoevenHong LiangYong ZhouGerald R.V. HammondJohn F. HancockKwang-jin Cho

Radiation Therapy Generates Release of Microvesicle Particles in Keratinocytes. International Journal of Radiation Oncology*Biology*Physics (2023)

E.J.V. TorralbaS. SinghW.R. RuckK. HenkelsC. RappJ.B. TraversR. Short

microvesicle particlesradiation oncologyradiationradiation therapydermatology

Radiation Therapy Produces Microvesicle Particle Release in Hacat Keratinocytes. Skin Research and Technology (2023)

Ericson John V. TorralbaShikshita SinghRobert F. ShortChristine M. RappKaren M. HenkelsRavi P. SahuJeffrey B. Travers

microvesicle particle releaseradiation oncologyradiationradiation therapyradiation biologydermatologyhacat keratinocytescell biology

Blocking K-Ras Interaction With the Plasma Membrane is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity. Frontiers in Molecular Biosciences (2021)

Karen M. HenkelsKristen M. RehlKwang-jin Cho

Avicin G is a Potent Sphingomyelinase Inhibitor and Blocks Oncogenic K- and H-Ras Signaling. Scientific Reports (2020)

Christian M. GarridoKaren M. HenkelsKristen M. RehlHong LiangYong ZhouJordan U. GuttermanKwang-jin Cho

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