Kadir Akdemir

Kadir Akdemir is a Senior Professor at The University of Texas MD Anderson Cancer Center. His research focuses on cancer genetics and genomics, with particular emphasis on tumor biology, oncogenes, and the molecular mechanisms underlying tumorigenesis. His recent work employs spatial transcriptomics to characterize evolving tumor microenvironments across the lung premalignancy-adenocarcinoma continuum, and investigates chromosomal instability in esophageal adenocarcinoma via a cGAS–chemokine–myeloid axis. He has also explored dual phagocytosis-checkpoint blockade in glioblastoma models and the immunologic response to oncolytic adenoviral infection in chordoma. His studies on KDM6A-mediated genomic instability and metabolic reprogramming in bladder cancer have significant therapeutic implications.