Faculty

Institution

Unit

Venue

Justin P. Whalley

Assistant Professor

Rosalind Franklin University of Medicine and Science

Affiliations

School Of Chicago Medical

Center For Cancer Cell Biology, Immunology And Infection

Department Of Clinical Sciences

Department Of Foundational Sciences And Humanities

Chicago Medical School

Foundational Sciences and Humanities

Midwest Proteome Center

School Of Chicago Medical

College of Health Professions

Department Of Biomedical Sciences

Department Of Physician Assistant

Foundational Sciences and Humanities

Department of Humanities & Health Care

Illinois Board of Higher Education

Rosalind Franklin University of Medicine and Science

Justin P. Whalley is an Assistant Professor at Rosalind Franklin University of Medicine and Science. His research integrates immunology, molecular biology, and genetics to investigate inflammation, immune responses, and cancer biology. Recent work includes proteomic endotyping of pleural infection and sepsis, revealing diverse neutrophilic responses and patient-specific plasma signatures. He also studies the yeast homolog of the juvenile Batten disease gene CLN3, employing TOR-dependent regulation to gain functional insights. His publications span high-impact venues including Science Translational Medicine, European Respiratory Journal, and The Journal of Immunology, with collaborative studies on aged brain multi-omics and SARS-CoV-2-induced pro-inflammatory transcriptional profiles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Justin P. Whalley

Rosalind Franklin University of Medicine and Science

Assistant Professor

You can click a keyword to filter the displayed items

immunology cell biology immune responses genetics inflammation respiratory medicine cell research immunity (medicine) cancer research molecular cell biology infectious diseases genome biology infectious respiratory disease cancer genetics proteomics sepsis covid-19 bioinformatics cellular therapy medical virology cancer discovery oncogenes immunogenetics innate immune system molecular immunology immune dysregulation granulocyte adaptive immune system genome instability cancer genomics yeast laboratory medicine stem cell research virus research biomolecular structure structural molecular biology autophagy cell transplantation molecular cancer gene editing crispr induced pluripotent stem cells viral pathogenesis antiviral responses immune-related gene polymorphism gene characterization immunologic diseases cellular immune responses immunopathology mutagenesis somatic variant acute medicine acute care immune mediators system immunology pulmonary diseases inflammatory markers pleural effusion single-cell analysis molecular regulation sepsis plasma proteome patient response high-throughput mass spectrometry genome-wide crispr/cas9-knockout sars-cov-2 infection structural variation epigenomic analysis innate immune activation transcriptome-wide disease associations distinct eqtl natural killer cells cd8 t cells immature neutrophil covid-19 lungs new insights mutagenic processes

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tor-Dependent Regulation of the Yeast Homolog of the Juvenile Batten Disease-Associated Gene Cln3. Microbial Cell (2026)

geneticsmolecular cell biologygene functiongene expressionmolecular geneticstor-dependent regulationgene regulationyeast homologmolecular biologygenome biologymolecular and cellular biologyyeast

Abstract 1760 Regulation and Functional Insights Into the Yeast Homolog of the Juvenile Batten Disease Protein. Journal of Biological Chemistry (2025)

geneticsmolecular cell biologygene expressionyeast homologfunctional insightsabstract 1760molecular biologymolecular and cellular biologyyeastfungal geneticscell and molecular biologymolecular regulation

Aged Brain Multi-Omic Integration Captures Immunometabolic and Sex Variation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

brain healthsex variationageingneuroscienceneuroscience of agingaging-associated diseasesaging cell

Pleural Fluid Proteomics From Patients With Pleural Infection Shows Signatures of Diverse Neutrophilic Responses: The Oxford Pleural Infection Endotyping Study (Torpids-2). European Respiratory Journal (2025)

inflammationinfectious diseasespleural fluid proteomicsproteomicsdiverse neutrophilic responsesbiomarkerspathogenesisproteome researchclinical proteomicsimmunologypleural infectionpleural effusiongranulocyteinflammatory markers

Systemic 4-1Bb Stimulation Augments Extrafollicular Memory B Cell Formation and Recall Responses During Plasmodium Infection 2954. The Journal of Immunology (2025)

immunity (medicine)malariaadaptive immune systemimmune responseshumoral responseplasmodium infection 2954pathogenesisrecall responsescell researchimmunologymemorycell biologyimmunological memory

High-Throughput Mass Spectrometry Maps the Sepsis Plasma Proteome and Differences in Patient Response. Science Translational Medicine (2024)

Yuxin MiKatie L. BurnhamPhilip D. CharlesRaphael HeiligIolanda VendrellJustin WhalleyHew D. TorranceDavid B. AntcliffeShaun M. MayMatt J. NevilleGeorgina BerridgePaula HuttonCyndi G. GeogheganJayachandran RadhakrishnanAlexey I. NesvizhskiiFengchao YuEmma E. DavenportStuart McKechnieRoger DaviesDavid J. P. O’CallaghanParind PatelAna G. del ArroyoFredrik KarpeAnthony C. GordonGareth L. AcklandCharles J. HindsRoman FischerJulian C. KnightNigel WebsterHelen GalleyJane TaylorSally HallJenni AddisonSian RoughtonHeather TennantAchyut GuleriNatalia WaddingtonDilshan ArawwawalaJohn DurcanAlasdair ShortKaren SwanSarah WilliamsSusan SmolenChristine Mitchell-InwangEmily ErringtonMaie TempletonPyda VenateshGeraldine WardMarie McCauleySimon BaudouinCharley HighamJasmeet SoarSally GrierElaine HallStephen BrettDavid KitsonRobert WilsonLaura MountfordJuan MorenoPeter HallJackie HewlettChristopher GarrardJulian MilloDuncan YoungPenny ParsonsAlex SmithsRoser Faras-ArrayaJasmeet SoarParizade RaymodeJonathan ThompsonSarah BowreySandra KazembeNatalie RichPrem AndreouDawn HalesEmma RobertsSimon FletcherMelissa RosbergenGeorgina GlisterJeronimo Moreno CuestaJulian BionJoanne MillarElsa Jane PerryHeather WillisNatalie MitchellSebastian RuelRonald CarreraJude WildeAnnette NilsonSarah LeesAtul KapilaNicola JacquesJane AtkinsonAbby BrownHeather ProwseAnton KrigeMartin BlandLynne BullockDonna HarrisonGary Mills

health sciencesmedicinerespiratory medicinesepsis plasma proteomeproteomicslaboratory medicinehigh-throughput mass spectrometrypatient responsetranslational medicinemass spectrometrysepsis

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery. Annals of Surgery (2023)

infectious respiratory diseaselung microbiomepulmonary diseasesrespiratory medicineinfectious diseasescritical careinfectious diseases (medical specialty)hospital infectionstranscriptomic approachpatient susceptibilityabdominal surgerysepsis

Mapping the Epigenomic Landscape of Human Monocytes Following Innate Immune Activation Reveals Context-Specific Mechanisms Driving Endotoxin Tolerance. BMC Genomics (2023)

immunity (medicine)endotoxin tolerancemolecular cell biologyimmune responsesinflammationimmune mediatorsepigenomic landscapesystem immunologyimmune dysregulationinnate immune systemsystems biologyimmunologyepigeneticscell biologyexperimental medicinehuman monocytesmolecular immunology

Sars-Cov-2 Infection Induces a Long-Lived Pro-Inflammatory Transcriptional Profile. Genome Medicine (2023)

viral pathogenesissars-cov-2inflammationinfectious diseasesmedical virologysars-cov-2 infectioncovid-19virus researchimmunologyantiviral responsesimmune responses

Single Cell Spatial Analysis Reveals Inflammatory Foci of Immature Neutrophil and Cd8 T Cells in Covid-19 Lungs. Nature Communications (2023)

infectious respiratory diseasepathologycellular immune responsesimmune responsesrespiratory medicineinflammationmedical virologycd8 t cellscovid-19 lungsimmature neutrophilcell researchimmunologyimmunopathologycell biologygranulocyte

1
2
10 / page

Justin P. Whalley

Assistant Professor

Rosalind Franklin University of Medicine and Science

Affiliations

School Of Chicago Medical

Center For Cancer Cell Biology, Immunology And Infection

Department Of Clinical Sciences

Department Of Foundational Sciences And Humanities

Chicago Medical School

Foundational Sciences and Humanities

Midwest Proteome Center

School Of Chicago Medical

College of Health Professions

Department Of Biomedical Sciences

Department Of Physician Assistant

Foundational Sciences and Humanities

Department of Humanities & Health Care

Illinois Board of Higher Education

Rosalind Franklin University of Medicine and Science

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Justin P. Whalley

Rosalind Franklin University of Medicine and Science

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tor-Dependent Regulation of the Yeast Homolog of the Juvenile Batten Disease-Associated Gene Cln3. Microbial Cell (2026)

geneticsmolecular cell biologygene functiongene expressionmolecular geneticstor-dependent regulationgene regulationyeast homologmolecular biologygenome biologymolecular and cellular biologyyeast

Abstract 1760 Regulation and Functional Insights Into the Yeast Homolog of the Juvenile Batten Disease Protein. Journal of Biological Chemistry (2025)

Aged Brain Multi-Omic Integration Captures Immunometabolic and Sex Variation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

brain healthsex variationageingneuroscienceneuroscience of agingaging-associated diseasesaging cell

Systemic 4-1Bb Stimulation Augments Extrafollicular Memory B Cell Formation and Recall Responses During Plasmodium Infection 2954. The Journal of Immunology (2025)

immunity (medicine)malariaadaptive immune systemimmune responseshumoral responseplasmodium infection 2954pathogenesisrecall responsescell researchimmunologymemorycell biologyimmunological memory

High-Throughput Mass Spectrometry Maps the Sepsis Plasma Proteome and Differences in Patient Response. Science Translational Medicine (2024)

health sciencesmedicinerespiratory medicinesepsis plasma proteomeproteomicslaboratory medicinehigh-throughput mass spectrometrypatient responsetranslational medicinemass spectrometrysepsis

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery. Annals of Surgery (2023)

Mapping the Epigenomic Landscape of Human Monocytes Following Innate Immune Activation Reveals Context-Specific Mechanisms Driving Endotoxin Tolerance. BMC Genomics (2023)

Sars-Cov-2 Infection Induces a Long-Lived Pro-Inflammatory Transcriptional Profile. Genome Medicine (2023)

viral pathogenesissars-cov-2inflammationinfectious diseasesmedical virologysars-cov-2 infectioncovid-19virus researchimmunologyantiviral responsesimmune responses

Single Cell Spatial Analysis Reveals Inflammatory Foci of Immature Neutrophil and Cd8 T Cells in Covid-19 Lungs. Nature Communications (2023)

1
2
10 / page