Faculty

Institution

Unit

Venue

J Lu

Professor Professor of Pharmacology

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Pharmacology

J Lu is currently serving as a Pharmacology Professor Professor of Pharmacology at Pennsylvania State University.

Honors

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Experiences

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Education

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J Lu

Pennsylvania State University

Professor Professor of Pharmacology

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cancer research oncology pharmacology cancer biology medicinal research tumor biology urology cancer treatment prostate cancer molecular cancer cancer cells carcinogenesis cancer care anti-cancer agents oncogenes medicine cancer genetics tumor targeting cell biology enzyme inhibition cancer growth cancer genomics cellular therapy apoptosis cancer management cancer imaging lung cancer genitourinary cancers breast cancer cell death medicinal chemistry cancer prevention vascular biology leukemia oncogenic agent thoracic oncology mammalian biology skin cancer treatment and prevention lung tumorigenesis phytotherapy research clinical nutrition cancer risk medical nutrition nutritional sciences signaling pathways methylseleninic acid prostate cancer cells pharmacotherapy clinical medicine drug targeting endocrine oncology cell regulation herbal medicine cancer chemoprevention transgenic adenocarcinoma in vivo systems mammary gland pathway analysis nutrient physiology cell cycle knockout mice immunotoxicology inhalation toxicology mammary cancer promotion androgen receptor cohort studies methyl selenium-induced apoptosis key executors sulfone metabolite mammary cancer selenium-induced inhibition chemopreventive levels growth inhibitory effects selenite induction dna strand breaks metabolomic profiling selenium deficiency metabolomics

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Double-Blinded, Placebo-Controlled, Cross-Over Pilot Trial in Healthy Men to Study the Effects of Angelica Gigas Herbal Supplement on Prostate Cancer–Relevant Inflammatory Cytokines.. Journal of Clinical Oncology (2024)

Anne-Laure StrongDeepkamal N. KareliaTodd D. SchellDiane HershockTongyao FanDongxiao SunJunjia ZhuElizabeth ProctorCheng JiangMonika JoshiJunxuan Lu

prostate cancertreatment and preventionmedicinecancer carecancer managementhealthy menclinical mycologycancer researchurologypreventive medicinecross-over pilot trialcancer treatmentcomplementary medicinepharmacologyherbal medicineclinical trialsoncologyclinical researchmedicinal researchexperimental medicine

Angelica Herbal Supplement Agn-Cogni.Q Acute Dose Safety and Pharmacokinetics (Pk) Dose-Response in Patients With Prostate Cancer (Pk Dose Trial).. Journal of Clinical Oncology (2023)

Monika JoshiJay D. RamanXin LiuDoris ShankTodd D. SchellJiangang Jason LiaoJunxuan Lu

pharmacologycancer carepharmacokineticsradiation oncologyurologyoncologycancer treatmentprostate cancer

Cannabinoids as Potential Cancer Therapeutics: The Concentration Conundrum. Cannabis and Cannabinoid Research (2023)

Nurgul Carkaci-SalliWesley M. Raup-KonsavageDeepkamal KareliaDongxiao SunCheng JiangJunxuan LuKent E. Vrana

oncologypharmacologyconcentration conundrum

Data From Kava Blocks 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone–Induced Lung Tumorigenesis in Association With Reducing I O Sup 6 /Sup /I -Methylguanine Dna Adduct in a/J Mice. (2023)

Pablo LeitzmanSreekanth C. NarayanapillaiSilvia BalboBo ZhouPramod UpadhyayaAhmad Ali ShaikM. Gerard O'SullivanStephen S. HechtJunxuan LuChengguo Xing

medicinal chemistrycell biologylung tumorigenesiscancer genomicsanti-cancer agentscancer biologycancer researchcancer growthlung cancertumor biologypharmacologythoracic oncologyliver cancergeneticscancer discoverycancer imagingoncologyoncogenescancer cells

Data From Role of P53-Senescence Induction in Suppression of Lncap Prostate Cancer Growth by Cardiotonic Compound Bufalin. (2023)

Yong ZhangYinhui DongMichael W. MelkusShutao YinSu-Ni TangPeixin JiangKartick PramanikWei WuSangyub KimMin YeHongbo HuJunxuan LuCheng Jiang

cellular senescencecell deathcancer geneticsprostate cancermolecular cancercardiotonic compound bufalincancer researchurologycancer growthfunctional modificationcell regulationtumor biologygene expressionpharmacologyenzyme inhibitionmolecular biologyoncologyoncogenescancer cells

Opportunities and Challenges of Kava in Lung Cancer Prevention. International Journal of Molecular Sciences (2023)

Breanne FreemanJessica MamallapalliTengfei BianKayleigh BallasAllison LynchAlexander ScalaZhiguang HuoKristianna M. FredenburgAdriaan W. BruijnzeelCarolyn J. BagloleJunxuan LuRamzi G. SalloumJohn MalatyChengguo Xing

public healthtreatment and preventionlung cancer preventionglobal healthrespiratory medicinelung cancercancer preventionhealth policy

Supplementary Tables and Figures From the Impact of One-Week Dietary Supplementation With Kava on Biomarkers of Tobacco Use and Nitrosamine-Based Carcinogenesis Risk Among Active Smokers. (2023)

Yi WangSreekanth C. NarayanapillaiKatelyn M. TessierLori G. StrayerPramod UpadhyayaQi HuRick KingstonRamzi G. SalloumJunxuan LuStephen S. HechtDorothy K. HatsukamiNaomi FujiokaChengguo Xing

public healthcarcinogenesisone-week dietary supplementationcancer researchsupplementary tablesbiostatisticsoncologynitrosamine-based carcinogenesis risknutritional sciencesactive smokershealth sciencestobacco controldietary healthtobacco use

Assessing the Antinociceptive Effects and Tolerance Development of Decursinol in Nociceptive, Inflammatory, and Neuropathic Pain. The FASEB Journal (2022)

LaTaijah CrawfordAngela Henderson‐RedmondSangyub KimDeepkamal KareliaDiana SepulvedaJunxuan LuDaniel Morgan

physiologyneuropathic painpharmacologytolerance developmenttreatment effectsantinociceptive effectsneuroscienceinflammation

In Vivo Structure‐Activity Relationship of Dihydromethysticin in Reducing Nicotine‐Derived Nitrosamine Ketone (Nnk)‐Induced Lung Dna Damage Against Lung Carcinogenesis in a/J Mice. ChemMedChem (2022)

Santanu HatiQi HuZhiguang HuoJunxuan LuChengguo Xing

nicotine-derived nitrosamine ketonepharmacologylung carcinogenesiscancer biologyradiation oncologycancer researchlung dna damagemolecular biologyoncologyoncogenic agentmedicinal researchdna repairchemoprevention strategieslung cancergenome instabilitymolecular medicineinhalation toxicology

Seleno‐Aspirin Compound as‐10 Promotes Histone Acetylation Ahead of Suppressing Androgen Receptor Transcription, G1 Arrest, and Apoptosis of Prostate Cancer Cells. The Prostate (2022)

Deepkamal N. KareliaSangyub KimDaniel PlanoArun K. SharmaCheng JiangJunxuan Lu

prostate cancer cellsprostate cancerneurologymedicinetumor targetingmolecular canceranti-cancer agentsandrogen receptor transcriptioncancer researchurologytumor suppressorscell regulationtumor biologyreceptorsgenitourinary cancersoncologyoncogenesmedicinal researchcancer cellscellular therapy

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J Lu

Professor Professor of Pharmacology

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Pharmacology

J Lu is currently serving as a Pharmacology Professor Professor of Pharmacology at Pennsylvania State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

J Lu

Pennsylvania State University

Professor Professor of Pharmacology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Anne-Laure StrongDeepkamal N. KareliaTodd D. SchellDiane HershockTongyao FanDongxiao SunJunjia ZhuElizabeth ProctorCheng JiangMonika JoshiJunxuan Lu

Angelica Herbal Supplement Agn-Cogni.Q Acute Dose Safety and Pharmacokinetics (Pk) Dose-Response in Patients With Prostate Cancer (Pk Dose Trial).. Journal of Clinical Oncology (2023)

Monika JoshiJay D. RamanXin LiuDoris ShankTodd D. SchellJiangang Jason LiaoJunxuan Lu

pharmacologycancer carepharmacokineticsradiation oncologyurologyoncologycancer treatmentprostate cancer

Cannabinoids as Potential Cancer Therapeutics: The Concentration Conundrum. Cannabis and Cannabinoid Research (2023)

Nurgul Carkaci-SalliWesley M. Raup-KonsavageDeepkamal KareliaDongxiao SunCheng JiangJunxuan LuKent E. Vrana

oncologypharmacologyconcentration conundrum

Data From Kava Blocks 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone–Induced Lung Tumorigenesis in Association With Reducing I O Sup 6 /Sup /I -Methylguanine Dna Adduct in a/J Mice. (2023)

Pablo LeitzmanSreekanth C. NarayanapillaiSilvia BalboBo ZhouPramod UpadhyayaAhmad Ali ShaikM. Gerard O'SullivanStephen S. HechtJunxuan LuChengguo Xing

Data From Role of P53-Senescence Induction in Suppression of Lncap Prostate Cancer Growth by Cardiotonic Compound Bufalin. (2023)

Yong ZhangYinhui DongMichael W. MelkusShutao YinSu-Ni TangPeixin JiangKartick PramanikWei WuSangyub KimMin YeHongbo HuJunxuan LuCheng Jiang

Opportunities and Challenges of Kava in Lung Cancer Prevention. International Journal of Molecular Sciences (2023)

public healthtreatment and preventionlung cancer preventionglobal healthrespiratory medicinelung cancercancer preventionhealth policy

Supplementary Tables and Figures From the Impact of One-Week Dietary Supplementation With Kava on Biomarkers of Tobacco Use and Nitrosamine-Based Carcinogenesis Risk Among Active Smokers. (2023)

Yi WangSreekanth C. NarayanapillaiKatelyn M. TessierLori G. StrayerPramod UpadhyayaQi HuRick KingstonRamzi G. SalloumJunxuan LuStephen S. HechtDorothy K. HatsukamiNaomi FujiokaChengguo Xing

Assessing the Antinociceptive Effects and Tolerance Development of Decursinol in Nociceptive, Inflammatory, and Neuropathic Pain. The FASEB Journal (2022)

LaTaijah CrawfordAngela Henderson‐RedmondSangyub KimDeepkamal KareliaDiana SepulvedaJunxuan LuDaniel Morgan

physiologyneuropathic painpharmacologytolerance developmenttreatment effectsantinociceptive effectsneuroscienceinflammation

Santanu HatiQi HuZhiguang HuoJunxuan LuChengguo Xing

Seleno‐Aspirin Compound as‐10 Promotes Histone Acetylation Ahead of Suppressing Androgen Receptor Transcription, G1 Arrest, and Apoptosis of Prostate Cancer Cells. The Prostate (2022)

Deepkamal N. KareliaSangyub KimDaniel PlanoArun K. SharmaCheng JiangJunxuan Lu

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