Faculty

Institution

Unit

Venue

Jun Li

The University of Texas MD Anderson Cancer Center

Affiliations

Metabolomics Core Facility

Department Of Bioinformatics And Computational Biology

The University of Texas MD Anderson Cancer Center

Jun Li is a Senior Professor at The University of Texas MD Anderson Cancer Center. His research integrates cancer genomics, functional proteomics, and computational oncology to dissect tumor biology and heterogeneity. Recent breakthroughs include DrBioRight 2.0, an LLM-powered bioinformatics chatbot for large-scale cancer proteomics analysis, and precision proteogenomics studies revealing the pan-cancer impact of germline variants. His work also encompasses the development of the Cancer Proteome Atlas and the MDA-OPC prospective cohort for oropharynx cancer outcomes. Li's contributions bridge molecular oncology with AI-driven data analysis, advancing precision medicine and cancer genetics.

Honors

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Experiences

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Education

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Jun Li

The University of Texas MD Anderson Cancer Center

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cancer research cancer biology cancer genomics oncology molecular biology cell biology tumor biology cancer genetics genetics genomics cancer cells proteomics genome biology molecular cancer systems biology bioinformatics oncogenes medicinal research cancer discovery proteome research gene expression protein science molecular cell biology thoracic oncology tumor heterogeneity functional genomics clinical proteomics cancer care protein bioinformatics gynecologic oncology cellular therapy cancer imaging genome analysis proteomic technologies human cancers molecular diagnostics signaling pathways cancer growth hematological malignancies cancer treatment omics datasets cellular biology long non-coding rna pathway analysis cell regulation translational proteomics cancer types pan-cancer analysis comprehensive molecular characterization tumor targeting computational genomics medical genetics molecular characterization epigenomics epidemiology of cancer rna biology mutagenesis large-scale datasets oncogenic agent genitourinary cancers cancer genome atlas pan-cancer proteomic perspective comprehensive characterization a-to-i rna mitochondrial genomes reverse-phase protein arrays cancer management kidney research genomic medicine cancer risk cell-of-origin patterns molecular classification oncogenic dedifferentiation cancer aneuploidy comprehensive analysis tumor exomes

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 6303: Drbioright: An AI-Driven Chatbot for Cancer Data Analysis. Cancer Research (2025)

artificial intelligencehealth informaticsbiomedical informaticsai healthcarecancer data analysisdigital medicineintelligent computingdata sciencesystems biologychatbotspersonalized medicine

Abstract B057: Drbioright: An AI Chat Assistant Enabling Scalable and Flexible Multi-Omics Analysis in Cancer. Clinical Cancer Research (2025)

translational bioinformaticsmulti-omics studiescomputational biologypathologybiomedical informaticsflexible multi-omics analysisabstract b057molecular informaticsomics datasetscancer researchai chat assistantsystems biologyomicsomics integrationbioinformaticsmultiomics

Drbioright 2.0: An Llm-Powered Bioinformatics Chatbot for Large-Scale Cancer Functional Proteomics Analysis. Nature Communications (2025)

Wei LiuJun LiYitao TangYining ZhaoChaozhong LiuMeiyi SongZhenlin JuShwetha V. KumarYiling LuRehan AkbaniGordon B. MillsHan Liang

nlp taskscientific communicationbiomedical informaticstumor biologyproteomicsdeep learningcancer imagingcancer discoverymachine learning researchprotein bioinformaticsllm-powered bioinformatics chatbotsystems biologychatbotscancer genomicsbioinformaticsproteome research

Precision Proteogenomics Reveals Pan-Cancer Impact of Germline Variants. Cell (2025)

somatic variantgenomicsmolecular cancercarcinogenesismolecular diagnosticscancer discoveryprecision proteogenomicsgeneticsomicstumor heterogeneitycancer genomicsgenome biology

Stiefel MD Anderson Oropharynx Cancer (Mda-Opc) Cohort: A Single-Institution, Prospective Longitudinal Outcomes Study. BMJ Open (2025)

radiation oncologyoral pathologycancer researchoral cancerepidemiology of cancermedicineprospective longitudinal outcomescancer careoncology

Abstract 4931: The Cancer Proteome Atlas: Expanded Datasets and Empowered With an AI-Driven Chatbot. Cancer Research (2024)

Han LiangWei LiuJun LiYitao Tang

cancer proteome atlascancer researchai-driven chatbot

Abstract Lb003: Comprehensive Multi-Omics Analysis Unveils Nfe2L2/Keap1 Mutations as Key Drivers of Treatment Resistance in Esophageal Squamous Cell Carcinoma During Chemoradiotherapy. Cancer Research (2024)

Kuaile ZhaoHu ChenZhenzhen XunJiaying DengYikai LuoJinjun YeJunqiang ChenWeiwei ChenJun LiHan Liang

treatment resistancetherapy resistanceesophageal cancercancer researchmolecular biology

A Protein Expression Atlas on Tissue Samples and Cell Lines From Cancer Patients Provides Insights Into Tumor Heterogeneity and Dependencies. Nature Cancer (2024)

Jun LiWei LiuKamalika MojumdarHong KimZhicheng ZhouZhenlin JuShwetha V. KumarPatrick Kwok-Shing NgHan ChenMichael A. DaviesYiling LuRehan AkbaniGordon B. MillsHan Liang

proteomicscarcinogenesiscancer discoverycell linestissue samplescell biologybiologycancer researchmolecular biologycancer cellscancer patientstumoral pathologyoncogenestumor microenvironmentcancer biologyproteome researchearly detectionprotein expression atlascancer imagingtumor heterogeneitycancer genomicsoncology

Supplementary Video S1 From Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas. (2024)

Jun LiRehan AkbaniWei ZhaoYiling LuJohn N. WeinsteinGordon B. MillsHan Liang

cancer proteome atlasproteomicscancer biologycancer researchcancer discoverysystems biologyproteome research

Author Correction: Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers. Nature Genetics (2023)

Yuan YuanYoung Seok JuYoungwook KimJun LiYumeng WangChristopher J. YoonYang YangInigo MartincorenaChad J. CreightonJohn N. WeinsteinYanxun XuLeng HanHyung-Lae KimHidewaki NakagawaKeunchil ParkPeter J. CampbellHan LiangLauri A. AaltonenFederico AbascalAdam AbeshouseHiroyuki AburataniDavid J. AdamsNishant AgrawalKeun Soo AhnSung-Min AhnHiroshi AikataRehan AkbaniKadir C. AkdemirHikmat Al-AhmadieSultan T. Al-SedairyFatima Al-ShahrourMalik AlawiMonique AlbertKenneth AldapeLudmil B. AlexandrovAdrian AllyKathryn AlsopEva G. AlvarezFernanda AmarySamirkumar B. AminBrice AminouOle AmmerpohlMatthew J. AndersonYeng AngDavide AntonelloPavana AnurSamuel AparicioElizabeth L. AppelbaumYasuhito AraiAxel AretzKoji ArihiroShun-ichi AriizumiJoshua ArmeniaLaurent ArnouldSylvia AsaYassen AssenovGurnit AtwalSietse AukemaJ. Todd AumanMiriam R. R. AurePhilip AwadallaMarta AymerichGary D. BaderAdrian Baez-OrtegaMatthew H. BaileyPeter J. BaileyMiruna BalasundaramSaianand BaluPratiti BandopadhayayRosamonde E. BanksStefano BarbiAndrew P. BarbourJonathan BarenboimJill Barnholtz-SloanHugh BarrElisabet BarreraJohn BartlettJavier BartolomeClaudio BassiOliver F. BatheDaniel BaumhoerPrashant BaviStephen B. BaylinWojciech BazantDuncan BeardsmoreTimothy A. BeckSam BehjatiAndreas BehrenBeifang NiuCindy BellSergi BeltranChristopher BenzAndrew BerchuckAnke K. BergmannErik N. BergstromBenjamin P. BermanDaniel M. BerneyStephan H. BernhartRameen BeroukhimMario Berrios

molecular geneticshuman cancershuman geneticsgeneticsgenomicscancer researchmitochondrial genomesmolecular biologymolecular cancersystems biologymedical geneticscancer biologygenome biologygenome analysisleukemiacomprehensive molecular characterizationauthor correctioncancer geneticscancer genomicsoncology

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Jun Li

The University of Texas MD Anderson Cancer Center

Affiliations

Metabolomics Core Facility

Department Of Bioinformatics And Computational Biology

The University of Texas MD Anderson Cancer Center

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jun Li

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 6303: Drbioright: An AI-Driven Chatbot for Cancer Data Analysis. Cancer Research (2025)

artificial intelligencehealth informaticsbiomedical informaticsai healthcarecancer data analysisdigital medicineintelligent computingdata sciencesystems biologychatbotspersonalized medicine

Abstract B057: Drbioright: An AI Chat Assistant Enabling Scalable and Flexible Multi-Omics Analysis in Cancer. Clinical Cancer Research (2025)

Drbioright 2.0: An Llm-Powered Bioinformatics Chatbot for Large-Scale Cancer Functional Proteomics Analysis. Nature Communications (2025)

Wei LiuJun LiYitao TangYining ZhaoChaozhong LiuMeiyi SongZhenlin JuShwetha V. KumarYiling LuRehan AkbaniGordon B. MillsHan Liang

Precision Proteogenomics Reveals Pan-Cancer Impact of Germline Variants. Cell (2025)

somatic variantgenomicsmolecular cancercarcinogenesismolecular diagnosticscancer discoveryprecision proteogenomicsgeneticsomicstumor heterogeneitycancer genomicsgenome biology

Stiefel MD Anderson Oropharynx Cancer (Mda-Opc) Cohort: A Single-Institution, Prospective Longitudinal Outcomes Study. BMJ Open (2025)

radiation oncologyoral pathologycancer researchoral cancerepidemiology of cancermedicineprospective longitudinal outcomescancer careoncology

Abstract 4931: The Cancer Proteome Atlas: Expanded Datasets and Empowered With an AI-Driven Chatbot. Cancer Research (2024)

Han LiangWei LiuJun LiYitao Tang

cancer proteome atlascancer researchai-driven chatbot

Kuaile ZhaoHu ChenZhenzhen XunJiaying DengYikai LuoJinjun YeJunqiang ChenWeiwei ChenJun LiHan Liang

treatment resistancetherapy resistanceesophageal cancercancer researchmolecular biology

A Protein Expression Atlas on Tissue Samples and Cell Lines From Cancer Patients Provides Insights Into Tumor Heterogeneity and Dependencies. Nature Cancer (2024)

Jun LiWei LiuKamalika MojumdarHong KimZhicheng ZhouZhenlin JuShwetha V. KumarPatrick Kwok-Shing NgHan ChenMichael A. DaviesYiling LuRehan AkbaniGordon B. MillsHan Liang

Supplementary Video S1 From Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas. (2024)

Jun LiRehan AkbaniWei ZhaoYiling LuJohn N. WeinsteinGordon B. MillsHan Liang

cancer proteome atlasproteomicscancer biologycancer researchcancer discoverysystems biologyproteome research

Author Correction: Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers. Nature Genetics (2023)

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