Faculty

Institution

Unit

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Julie M. George

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Gynecologic Oncology And Reproductive Medicine

Julie M. George is a Senior Professor at The University of Texas MD Anderson Cancer Center. Her research focuses on tumor biology, cancer immunology, and metabolic vulnerabilities in pancreatic and gastrointestinal malignancies. Recent breakthroughs include identifying long-chain sulfatide enrichment as a metabolic target in IPMN-associated pancreatic cancers and mapping ferroptosis-linked metastatic gastric cancer progression. Her work also explores YAP1-driven plasticity in relapsed small cell lung cancer and the impact of gut microbiome metabolites on CAR T-cell therapy responses. She has developed protocols for isolating ascites-derived cells and extracellular vesicles from peritoneal metastases, advancing translational oncology and precision medicine.

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Julie M. George

The University of Texas MD Anderson Cancer Center

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cancer research oncology immunology cancer biology health sciences tumor biology cell biology cancer cells proteomics medicinal research molecular cancer molecular diagnostics pancreatic cancer molecular biology lung cancer thoracic oncology oncogenes clinical proteomics immune responses cancer immunotherapy cancer care cancer genomics protein science cancer discovery gastrointestinal oncology genomics proteome research biomarker discovery cancer detection genome biology digestive diseases molecular gastroenterology cancer risk prognostic biomarkers cancer treatment respiratory medicine protein mass spectrometry cancer genetics clinical immunology bronchial neoplasm clinical biochemistry proteomic technologies early detection cellular immune responses tumor heterogeneity genomic medicine genitourinary cancers cancer immunosurveillance translational proteomics gastric adenocarcinoma malignant disease medical genetics adaptive immune system disease progression gene expression profiling innate immune system disease risk assessment rna biology chromosome biology cytogenetics microarray data analysis lung adenocarcinoma pancreatic cancer patients biomarker panel gastric adenocarcinoma progression protein microarrays coronary heart disease multi-analyte blood test tumor microbiome diversity validation study earlier detection tumor dna systemic lupus erythematosus clear cell biological behavior cancer-specific exosomal cargo

Notable Scholarly Works

Notable Federal Grants

Collaborators

Kap1 Promotes Gastric Adenocarcinoma Progression by Activating Hippo/Yap1 Signaling via Binding to Hnrnpab. Cancer Letters (2025)

Shumei SongYibo FanGengyi ZouLongfei HuoJanani KumarYuan LiRuiping WangEnyu DaiJiankang JinAiling W ScottShan ShaoMelissa Pool PizziJody V VykoukalHiryuki KatayamaSamir HanashGeorge A CalinXing ZhangMin Gyu LeeZhenning WangYuan-Hung LoQiong GanRebecca E WatersFeng YinLinghua WangXiaodong ChengJaffer A AjaniShilpa S Dhar

gastrointestinal oncologypathologydisease progressionmolecular cancertumor microenvironmentcancer researchcancer immunotherapycancer treatmentgastric adenocarcinoma progressiontumor biologyimmunologysignaling pathwaystumoral pathologysystems biologycancer discoverymolecular gastroenterologyoncologyoncogenescancer cells

Long-Chain Sulfatide Enrichment is an Actionable Metabolic Vulnerability in Intraductal Papillary Mucinous Neoplasm (Ipmn)-Associated Pancreatic Cancers. Gut (2025)

Yihui ChenRiccardo BallaròMarta SansFredrik Ivar ThegeMingxin ZuoRongzhang DouJimin MinMichele Yip-SchneiderJ ZhangRanran WuEhsan IrajizadYuki MakinoKimal I RajapaksheHamid K RudsariMark W HurdRicardo A León-LetelierHiroyuki KatayamaEdwin OstrinJody VykoukalJennifer B DennisonKim-Anh DoSamir M HanashRobert A WolffPaolo A GuerreroMichael KimC Max SchmidtAnirban MaitraJohannes F Fahrmann

mutant krasradiation oncologycancer researchmolecular cancerpancreatic cancercancer discoverymolecular diagnosticsoncologymass spectrometrycancer cellsmetabolomicstumor heterogeneitycancer biologypathologytumor biologysulfatide enrichment

Protocol for Isolating Patient-Derived Ascites Cells and Extracellular Vesicles From Gastric Cancer Peritoneal Metastases. STAR Protocols (2025)

extracellular microvesiclesmetastasispatient-derived ascites cellsextracellular vesiclescancer discoveryoncologygastroenterologycancer cellsgastrointestinal oncologycancer biologypathologytumor biologycell biology

Pt1.04.03 the Leap Study: A Biospecimen Bank for Validation of Liquid Biomarkers in a Lung Cancer Screening Cohort. Journal of Thoracic Oncology (2025)

leap studymedicinebiomarker targetbiomarkerspharmacologythoracic oncologybiomarker discoverycancer discoverybiostatisticsoncologymolecular diagnosticsliquid biomarkerslung cancerbiospecimen bankclinical proteomics

Yap1 Defines an Emergent, Plastic Population of Relapsed Small Cell Lung Cancer. Journal of Thoracic Oncology (2025)

bronchial neoplasmcancer biologythoracic oncologyyap1 definesplastic populationoncologyoncogenestumor heterogeneitylung cancerpathologytumor biologycell biology

Abstract 446: Integrated Spatial Transcriptomics and Lipidomics Analyses of Intraductal Papillary Mucinous Neoplasm Identifies Enrichment of Long Chain Sulfatide as an Early Metabolic Alteration. Cancer Research (2024)

Yihui ChenMarta SansFredrik ThegeRongzhang DouJimin MinMichele Yip-SchneiderJianjun ZhangRanran WuEhsan IrajizadYuki MakinoKimal RajapaksheMark HurdRicardo León-LetelierJody VykoukalJennifer DennisonKim-Anh DoRobert WolffPaola GuerreroMichael KimMax SchmidtAnirban MaitraSamir HanashJohannes Fahrmann

tumor microenvironmenttumoral pathologycancer researchmolecular cancerpancreatic cancerpdac tissuesvisium workflowmolecular pathologycancer imagingmolecular diagnosticsbiomedical analysiscancer cellsmetabolomicstumor heterogeneitypathologytumor biologylipidomic analysescell biology

Abstract A014: Combinations of Previously Reported Biomarkers Achieve Improved Sensitivity and Specificity of Detection of Early Stage Pancreatic Ductal Adenocarcinoma. Cancer Research (2024)

Brian HaabLu QianBen StaalManeesh JainJohannes FahrmannChristine WorthingtonDenise ProsserLiudmila VelokokhatnayaCamden LopezRunlong TangMark HurdGopalakrishnan NatarajanSushil KumarLynette SmithSamir HanashSurinder BatraAnirban MaitraAnna LokshinYing HuangRandall E. BrandLiudmila Velokokhatnaya

biomarkerscancer careradiation oncologycancer researchcancer imagingbiostatisticsoncologyclinical researchmolecular diagnosticsmedicinal researchinnovative diagnosticsearly detectioncancer biologycancer screeningtumor biologyhealth sciencescancer detection

Abstract Pr-13: Disruption of Sulfatide Metabolism by Targeting Ugt8 is an Actionable Metabolic Vulnerability for Pancreatic Cancer Early Interception. Cancer Research (2024)

Riccardo BallaròYihui ChenFredrik I ThegeRongzhang DouJimin MinMichele Yip-SchneiderJianjun ZhangRanran WuEhsan IrajizadYuki MakinoKimal I RajapaksheMark W HurdRicardo A León-LetelierEdwin OstrinJody VykoukalJennifer B DennisonKim-Anh DoSamir HanashRobert A WolffPaola A GuerreroMichael P KimC Max SchmidtAnirban MaitraJohannes F Fahrmann

gnas ipmn cellscancer researchmolecular cancerpancreatic cancerpdac early interceptioncancer discoverymolecular gastroenterologyoncogenescancer cellsmetabolomicsmetabolic pathwayscancer biologyabstract pr-13tumor biologybiochemistrycell biology

Antibiotic-Induced Loss of Gut Microbiome Metabolic Output Correlates With Clinical Responses to Car T-Cell Therapy. Blood (2024)

immunologymicrobiomegut microbesdigestive diseasesgut-organ axisclinical microbiologymucosal immunologyantibioticsclinical responsest-cell therapydysbiosisinfectious diseasesmicrobiologyantibiotic-induced loss

A Rigorous Multi-Laboratory Study of Known Pdac Biomarkers Identifies Increased Sensitivity and Specificity Over Ca19-9 Alone. Cancer Letters (2024)

Brian HaabLu QianBen StaalManeesh JainJohannes FahrmannChristine WorthingtonDenise ProsserLiudmila VelokokhatnayaCamden LopezRunlong TangMark W HurdGopalakrishnan NatarajanSushil KumarLynette SmithSam HanashSurinder K BatraAnirban MaitraAnna LokshinYing HuangRandall E Brand

immunologyrigorous multi-laboratory studypharmacologybiomarkersbiomarker discoverycancer researchnucleic acid biomarkersoncologymedicinal researchprotein sciencehealth sciences

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Julie M. George

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Gynecologic Oncology And Reproductive Medicine

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Julie M. George

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Kap1 Promotes Gastric Adenocarcinoma Progression by Activating Hippo/Yap1 Signaling via Binding to Hnrnpab. Cancer Letters (2025)

Long-Chain Sulfatide Enrichment is an Actionable Metabolic Vulnerability in Intraductal Papillary Mucinous Neoplasm (Ipmn)-Associated Pancreatic Cancers. Gut (2025)

Protocol for Isolating Patient-Derived Ascites Cells and Extracellular Vesicles From Gastric Cancer Peritoneal Metastases. STAR Protocols (2025)

Pt1.04.03 the Leap Study: A Biospecimen Bank for Validation of Liquid Biomarkers in a Lung Cancer Screening Cohort. Journal of Thoracic Oncology (2025)

Yap1 Defines an Emergent, Plastic Population of Relapsed Small Cell Lung Cancer. Journal of Thoracic Oncology (2025)

bronchial neoplasmcancer biologythoracic oncologyyap1 definesplastic populationoncologyoncogenestumor heterogeneitylung cancerpathologytumor biologycell biology

Abstract A014: Combinations of Previously Reported Biomarkers Achieve Improved Sensitivity and Specificity of Detection of Early Stage Pancreatic Ductal Adenocarcinoma. Cancer Research (2024)

Abstract Pr-13: Disruption of Sulfatide Metabolism by Targeting Ugt8 is an Actionable Metabolic Vulnerability for Pancreatic Cancer Early Interception. Cancer Research (2024)

Antibiotic-Induced Loss of Gut Microbiome Metabolic Output Correlates With Clinical Responses to Car T-Cell Therapy. Blood (2024)

A Rigorous Multi-Laboratory Study of Known Pdac Biomarkers Identifies Increased Sensitivity and Specificity Over Ca19-9 Alone. Cancer Letters (2024)

immunologyrigorous multi-laboratory studypharmacologybiomarkersbiomarker discoverycancer researchnucleic acid biomarkersoncologymedicinal researchprotein sciencehealth sciences

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5
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10 / page