Faculty

Institution

Unit

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Joseph L. Johnson

Assistant Professor

University of Minnesota Duluth

Affiliations

Swenson College of Science and Engineering

Department Of Chemistry And Biochemistry

Joseph L. Johnson is currently serving as a Chemistry And Biochemistry Assistant Professor at University of Minnesota Duluth.

Honors

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Experiences

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Education

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Joseph L. Johnson

University of Minnesota Duluth

Assistant Professor

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organic synthesis pharmacology chemistry medicinal chemistry chemical synthesis stereoselective synthesis drug discovery anti-cancer agents cheminform abstract biomolecular engineering medicine efficient synthesis functionalized pyroglutamates scientific communication drug delivery cancer research natural products production research medicinal research molecular cancer scientific data biological macromolecules biomedical analysis protein science clinical proteomics cell research cellular biochemistry proteome research biomolecular structure drug development tumor targeting drug targeting therapeutic efficacy pharmaceutical chemistry natural product synthesis cancer treatment heterocyclic cell detection crystal structures vivo evaluation novel n-phenylindazolyl diarylureas anti-cancer evaluation triazole cinnamates baylis-hillman reaction concise synthesis biological evaluation anticancer agents dimerization hypothesis fluorescence microspectroscopy bace1b isoform process biochemistry proteomics biomolecules synthetic biology protein engineering structural molecular biology biophysical chemistry metabolic engineering enzymes biophysical review molecular science peptides bioanalysis chemical biology molecular biophysics molecular biology protein folding carbohydrate chemistry biological engineering computational biology biochemical engineering protein design biochemistry cell metabolism bioenergetics microbiology small molecules molecular informatics bioorganic chemistry biological chemistry protein structure systems biology structural biology biophysics molecular metabolism molecular modelling peptide science biotechnology advance biotechnology biochemical sciences enzyme inhibition

Notable Scholarly Works

Notable Federal Grants

Collaborators

Nitroxoline-O-Protected Derivatives Inhibit Metap2 and Activate Atf4 Through Mtorc1 to Inhibit Cancer Cell Growth. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Targeting Tumor Antioxidant Pathways With Novel Gstp1/M2 Inhibitors for Cancer Treatment. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Synthesis and Evaluation of Quinolino-Benzoxaboroles as Potential Antimicrobial Agents. International Journal of Organic Chemistry (2022)

Synthesis, in Vitro, and in Vivo Evaluation of Novel N-Phenylindazolyl Diarylureas as Potential Anti-Cancer Agents. Scientific Reports (2020)

Lucas N. SolanoGrady L. NelsonConor T. RonayneShirisha JonnalagaddaSravan K. JonnalagaddaKaija KottkeRobert ChitrenJoseph L. JohnsonManoj K. PandeySubash C. JonnalagaddaVenkatram R. Mereddy

production researchscientific communicationdrug deliverydrug developmenttumor targetingdrug targetinganti-cancer agentsvivo evaluationmedicinal researchmolecular cancermedicinal chemistrycancer researchnovel n-phenylindazolyl diarylureaspharmacologytherapeutic efficacyscientific datadrug discoverybiomolecular engineering

Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents. International Journal of Medicinal Chemistry (2018)

Grady L. NelsonMichael J. WilliamsShirisha JonnalagaddaMohammad A. AlamGautam MereddyJoseph L. JohnsonSravan K. Jonnalagadda

triazole cinnamatesbaylis-hillman reactionmedicinal chemistrychemical synthesispharmacologydrug discoveryorganic synthesis

Fluorescence Fluctuation Analysis of Bace1-Gfp Fusion Protein in Cultured Hek293 Cells. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2016)

Fluorescence Micro-Spectroscopy Assessment of the in Vitro Dimerization of Bace1-Gfp Fusion Protein in Cultured Cells. Biophysical Journal (2016)

biophysicsbiological macromoleculesbiomedical analysisbiological imagingprotein sciencecell biologymolecular imagingfluorescence spectroscopybioanalysiscell engineeringclinical proteomicscell researchfluorescencecellular biochemistrybiomolecular engineeringproteome researchcell and molecular biology

Fluorescence Microspectroscopy for Testing the Dimerization Hypothesis of Bace1 Protein in Cultured Hek293 Cells. (2016)

Ahmed HeikalJoseph JohnsonSpencer Gardeen

biological imagingdimerization hypothesiscell detectionfluorescence microspectroscopybiochemistry

An Efficient Synthesis of [2.2.1] Heterobicyclic Pyroglutamates. Journal of Heterocyclic Chemistry (2013)

Srinivas TekkamJoseph L. JohnsonSubash C. JonnalagaddaVenkatram R. Mereddy

efficient synthesischemical synthesischemistryorganic chemistryorganic synthesis

Application of a Bioinformatics-Based Approach to Identify Novel Putative in Vivo Bace1 Substrates. Biomedical Engineering and Computational Biology (2013)

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Joseph L. Johnson

Assistant Professor

University of Minnesota Duluth

Affiliations

Swenson College of Science and Engineering

Department Of Chemistry And Biochemistry

Joseph L. Johnson is currently serving as a Chemistry And Biochemistry Assistant Professor at University of Minnesota Duluth.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Joseph L. Johnson

University of Minnesota Duluth

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Nitroxoline-O-Protected Derivatives Inhibit Metap2 and Activate Atf4 Through Mtorc1 to Inhibit Cancer Cell Growth. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Targeting Tumor Antioxidant Pathways With Novel Gstp1/M2 Inhibitors for Cancer Treatment. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Synthesis and Evaluation of Quinolino-Benzoxaboroles as Potential Antimicrobial Agents. International Journal of Organic Chemistry (2022)

Synthesis, in Vitro, and in Vivo Evaluation of Novel N-Phenylindazolyl Diarylureas as Potential Anti-Cancer Agents. Scientific Reports (2020)

Lucas N. SolanoGrady L. NelsonConor T. RonayneShirisha JonnalagaddaSravan K. JonnalagaddaKaija KottkeRobert ChitrenJoseph L. JohnsonManoj K. PandeySubash C. JonnalagaddaVenkatram R. Mereddy

Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents. International Journal of Medicinal Chemistry (2018)

Grady L. NelsonMichael J. WilliamsShirisha JonnalagaddaMohammad A. AlamGautam MereddyJoseph L. JohnsonSravan K. Jonnalagadda

triazole cinnamatesbaylis-hillman reactionmedicinal chemistrychemical synthesispharmacologydrug discoveryorganic synthesis

Fluorescence Fluctuation Analysis of Bace1-Gfp Fusion Protein in Cultured Hek293 Cells. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2016)

Fluorescence Micro-Spectroscopy Assessment of the in Vitro Dimerization of Bace1-Gfp Fusion Protein in Cultured Cells. Biophysical Journal (2016)

Fluorescence Microspectroscopy for Testing the Dimerization Hypothesis of Bace1 Protein in Cultured Hek293 Cells. (2016)

Ahmed HeikalJoseph JohnsonSpencer Gardeen

biological imagingdimerization hypothesiscell detectionfluorescence microspectroscopybiochemistry

An Efficient Synthesis of [2.2.1] Heterobicyclic Pyroglutamates. Journal of Heterocyclic Chemistry (2013)

Srinivas TekkamJoseph L. JohnsonSubash C. JonnalagaddaVenkatram R. Mereddy

efficient synthesischemical synthesischemistryorganic chemistryorganic synthesis

Application of a Bioinformatics-Based Approach to Identify Novel Putative in Vivo Bace1 Substrates. Biomedical Engineering and Computational Biology (2013)

1
2
10 / page