Faculty

Institution

Unit

Venue

Jonathan Soboloff

Professor

Temple University

Affiliations

Lewis Katz School of Medicine

Basic Science Departments

Cancer and Cellular Biology

Medical Genetics and Molecular Biochemistry

Jonathan Soboloff is currently serving as a Basic Science S Professor at Temple University.

Honors

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Experiences

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Education

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Jonathan Soboloff

Temple University

Professor

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cell signaling neuroscience cell biology signal transduction physiology pharmacology gene expression membrane biology cell regulation tumor biology cellular physiology electrophysiology neurophysiology receptors melanoma medicinal research skin cancer molecular cell biology molecular physiology protein science bone research mammalian biology signaling pathways cancer biology brain stimulation mitochondrial function molecular regulation sensory science reproductive biology reproductive science vascular biology orthopaedic research stem cell research tumor suppressors reproductive physiology animal reproduction adaptive immune system cellular immune responses trpc channels redox biology pharmacotherapy leukemia reproductive medicine cellular biology gene regulation bone homeostasis cancer genetics cytokines stim proteins redox signaling experimental pharmacology protein assembly orthopedic biomechanics cell physiology myeloid neoplasia hemostasis calcium entry signals t-cell activation calcium signals hen granulosa cells arthritis-induced bone erosion molecular neurobiology redox chemistry clinical medicine clinical physiology muscle function innate immune system ion-selective pore crac channel receptor activation calcium store sensor mcu channel activity functional link orai-activating site distinct orai-coupling domains crac channel activation

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeting Trpc Channels for Control of Arthritis-Induced Bone Erosion. Science Advances (2025)

Suravi RayJamie L. McCallJin Bin TianJaepyo JeonAidan DouglasKendall TylerSiyao LiuKendyl BerryBrady NicewarnerCasey HallKlaus GroschnerBernadett BacsaWerner GeldenhuysMichael X. ZhuHarry C. BlairJohn B. BarnettJonathan Soboloff

arthritisrheumatologytrpc channelsbiomedical engineeringbone homeostasisscience advancearthritis-induced bone erosionbone research

Channelling Calcium Signals to Therapeutics. The Journal of Physiology (2024)

Grace E. StutzmannJonathan Soboloff

physiological researchcalcium signalsneuropharmacologyphysiologycell signalingelectrophysiologyneurosciencemolecular physiologyneurophysiologypharmacologyapplied physiologyhuman physiologydisease physiology

Enforced Expression of Mitochondrial Calcium Uniporter in Donor T Cells Abolishes Gvhd Progression. Blood (2024)

Ying WANGAlicia Huaze LiRuqayyah sanders-BraggsYan ZhouMimi ChenTien BuiHongfa ZhuNasheed HossainJonathan SoboloffJohn ElrodElizabeth O. HexnerYi Zhang

graft rejectionimmunologygvhd progressionmitochondrial calcium uniportergene expression

Molecular Regulation of Bone Turnover in Juvenile Idiopathic Arthritis: Animal Models, Cellular Features and Tnfα. Frontiers in Bioscience-Landmark (2024)

Harry C BlairJonathan SoboloffIrina L TourkovaJamie L. McCallSuravi RayMargalit E RosenkranzCristina SobacchiLisa J RobinsonJohn B Barnett

animal modelsbone turnoverrheumatologycellular featuresdevelopmental biologymolecular biologygeneticsjuvenile idiopathic arthritis

Preclinical Evaluation of Elp‐004 in Mice. Pharmacology Research & Perspectives (2024)

Jamie L. McCallWerner J. GeldenhuysLisa J. RobinsonMichelle R. WittPeter M. GannettBjörn C. G. SöderbergHarry C. BlairJonathan SoboloffJohn B. Barnett

veterinary medicinepharmacological researchpreclinical evaluationpharmacology

Tpc2 Controls Mitf Expression and Metastasis in Melanoma. Cell Calcium (2024)

M Raza ZaidiJonathan Soboloff

metastasistumor biologycell biologymelanomaskin cancermolecular biologyoncology

Abstract 1551: Geranylgeranyltransferase Inhibitors Selectively Inhibit Stim2-Dependent Orai Function. Journal of Biological Chemistry (2023)

Alexander ArmsteadScott GrossGabriel WingertAidan DouglasIgor AstsaturovJonathan Soboloff

inhibitory activityneuropharmacologymedicinal chemistrybiochemistrygeranylgeranyltransferase inhibitorsmolecular biologypharmacologymolecular pharmacologydrug discoverybiological chemistrytranslational pharmacologyenzyme inhibition

Abstract 2536: Intracellular Ctla4 Overexpression Promotes Melanoma Progression and Metastasis. Cancer Research (2023)

Hasan Raza KazmiXuan MoBo ZhouSarah Preston AlpScott GrossHassaan WajeehCarmen MeraliJohn ElrodJonathan SoboloffSalim MeraliM. Raza Zaidi

metastasistumor biologymelanoma progressioncancer immunotherapyimmunologycell biologymelanomadermatologymolecular cancerskin cancergenitourinary cancerscancer researchcancer geneticsoncologycancer biology

Data From Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of Ctla-4. (2023)

Xuan MoHanghang ZhangSarah PrestonKayla MartinBo ZhouNish VadaliaAna M. GameroJonathan SoboloffItalo TemperaM. Raza Zaidi

melanoma cellscell signalingimmunologycell biologymelanomaskin cancertranscription regulationdata sciencesignal transductiongene expressioncell regulationmolecular regulation

Dual Functions of Mitochondrial Calcium Uniporter in T Cell Alloimmunity. Blood (2023)

Ying WANGAlicia Huaze LiRuqayyah sanders-BraggsYan ZhouMimi ChenTien BuiHongfa ZhuJonathan SoboloffJohn ElrodElizabeth O HexnerYi Zhang

immunologycell biologyhematologymitochondrial calcium uniportermitochondrial functiondual functions

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Jonathan Soboloff

Professor

Temple University

Affiliations

Lewis Katz School of Medicine

Basic Science Departments

Cancer and Cellular Biology

Medical Genetics and Molecular Biochemistry

Jonathan Soboloff is currently serving as a Basic Science S Professor at Temple University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jonathan Soboloff

Temple University

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeting Trpc Channels for Control of Arthritis-Induced Bone Erosion. Science Advances (2025)

arthritisrheumatologytrpc channelsbiomedical engineeringbone homeostasisscience advancearthritis-induced bone erosionbone research

Channelling Calcium Signals to Therapeutics. The Journal of Physiology (2024)

Grace E. StutzmannJonathan Soboloff

Enforced Expression of Mitochondrial Calcium Uniporter in Donor T Cells Abolishes Gvhd Progression. Blood (2024)

Ying WANGAlicia Huaze LiRuqayyah sanders-BraggsYan ZhouMimi ChenTien BuiHongfa ZhuNasheed HossainJonathan SoboloffJohn ElrodElizabeth O. HexnerYi Zhang

graft rejectionimmunologygvhd progressionmitochondrial calcium uniportergene expression

Molecular Regulation of Bone Turnover in Juvenile Idiopathic Arthritis: Animal Models, Cellular Features and Tnfα. Frontiers in Bioscience-Landmark (2024)

Harry C BlairJonathan SoboloffIrina L TourkovaJamie L. McCallSuravi RayMargalit E RosenkranzCristina SobacchiLisa J RobinsonJohn B Barnett

animal modelsbone turnoverrheumatologycellular featuresdevelopmental biologymolecular biologygeneticsjuvenile idiopathic arthritis

Preclinical Evaluation of Elp‐004 in Mice. Pharmacology Research & Perspectives (2024)

Jamie L. McCallWerner J. GeldenhuysLisa J. RobinsonMichelle R. WittPeter M. GannettBjörn C. G. SöderbergHarry C. BlairJonathan SoboloffJohn B. Barnett

veterinary medicinepharmacological researchpreclinical evaluationpharmacology

Tpc2 Controls Mitf Expression and Metastasis in Melanoma. Cell Calcium (2024)

M Raza ZaidiJonathan Soboloff

metastasistumor biologycell biologymelanomaskin cancermolecular biologyoncology

Abstract 1551: Geranylgeranyltransferase Inhibitors Selectively Inhibit Stim2-Dependent Orai Function. Journal of Biological Chemistry (2023)

Alexander ArmsteadScott GrossGabriel WingertAidan DouglasIgor AstsaturovJonathan Soboloff

Abstract 2536: Intracellular Ctla4 Overexpression Promotes Melanoma Progression and Metastasis. Cancer Research (2023)

Hasan Raza KazmiXuan MoBo ZhouSarah Preston AlpScott GrossHassaan WajeehCarmen MeraliJohn ElrodJonathan SoboloffSalim MeraliM. Raza Zaidi

Data From Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of Ctla-4. (2023)

Xuan MoHanghang ZhangSarah PrestonKayla MartinBo ZhouNish VadaliaAna M. GameroJonathan SoboloffItalo TemperaM. Raza Zaidi

melanoma cellscell signalingimmunologycell biologymelanomaskin cancertranscription regulationdata sciencesignal transductiongene expressioncell regulationmolecular regulation

Dual Functions of Mitochondrial Calcium Uniporter in T Cell Alloimmunity. Blood (2023)

Ying WANGAlicia Huaze LiRuqayyah sanders-BraggsYan ZhouMimi ChenTien BuiHongfa ZhuJonathan SoboloffJohn ElrodElizabeth O HexnerYi Zhang

immunologycell biologyhematologymitochondrial calcium uniportermitochondrial functiondual functions

1
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4
5
11
10 / page

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Similar Faculty Members

Kamel Khalili

Institution

Temple University

neuroscience

neurodegenerative disease

Stephen D. Nimer

Institution

University of Miami

molecular biology

haematopoiesis

James R. Goldenring

Institution

Vanderbilt University

gastrointestinal oncology

gastroenterology

Albert Fornace

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Georgetown University

molecular biology

radiation oncology

Timothy Scott Blackwell, M.D.

Institution

Vanderbilt University

respiratory medicine

immunology

Donald McDonnell

Institution

Duke University

pharmacology

endocrinology

Harvey R. Herschman

Institution

University of California, Los Angeles

imaging genomics

cell biology

Amato J. Giaccia

Institution

Stanford University

radiation oncology

cancer biology

Sarah Spiegel

Institution

Virginia Commonwealth University

signaling pathway

cancer cell

Mohamed Trebak

Institution

University of Pittsburgh

circulatory physiology

protein science