Faculty

Institution

Unit

Venue

John Weldon

Associate Professor

Towson University

Affiliations

Jess & Mildred Fisher College of Science & Mathematics

Department of Biological Sciences

John Weldon is currently serving as a Biological Sciences Associate Professor at Towson University.

Honors

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Experiences

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Education

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John Weldon

Towson University

Associate Professor

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immunology toxins microbiology immune responses microbial toxins pathogenic bacteria antimicrobial agents immunotherapy recombinant immunotoxins immunotoxicology virulence factors toxinology mycotoxin research bacteria cellular therapy applied microbiology recombinant immunotoxin protein engineering biomolecular engineering cancer immunotherapy therapeutic targets biological macromolecules immunomodulation allergy synthetic biology cell death biomolecules clinical immunology molecular microbiology bacteriology microbial cell factory in vitro toxicology medicinal research antimicrobial compounds laboratory immunology immunologic mechanisms adaptive immune system immunochemistry protein biosynthesis gene editing crispr high activity low off-target toxicity furin-cleavable linker reproductive immunology cell transplantation antiviral research experimental medicine protein science humoral response immunopathology novel therapies molecular immunology vaccine design synthetic immunology protein chemistry protein function antimicrobial stewardship antibiotic adjuvant tissue culture student learning higher education teaching faculty professional development lymphocyte development innate immune system protease-resistant immunotoxin animal toxicity increased activity b-cell malignancies b-cell epitopes immunodominant t-cell epitope low nonspecific toxicity low immunogenicity high antitumor activity disulfide bond improved activity biophysics molecular biology biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Faculty Rewards From Course-Based Undergraduate Research Experiences (Cure) in Biochemistry. Journal of Microbiology and Biology Education (2025)

educationstem educationundergraduate researchmentorshiphigher educationmedicinechemistry educationstudent learninghigher education teachingfaculty rewardsfaculty professional development

Intracellular Trafficking of Furin Enhances Cellular Intoxication by Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. Biology Open (2025)

recombinant immunotoxinsantimicrobial agentsmycotoxin researchpathogenic bacteriapathogenesisimmunologyprotein secretiontoxinologymicrobial toxinsmicrobiologytoxinspathogensimmune responsesintracellular traffickingmicrobial pathogenesis

Abstract 1626 Cytotoxic T Lymphocyte-Mediated Killing of Factor VIII-Specific B Lymphocytes Using a Bispecific Immunoconjugate. Journal of Biological Chemistry (2024)

John WeldonMargaret ReganMatthew BonettDavid Scott

bispecific immunoconjugatecell deathimmunologybiochemistrylymphocyte-mediated killingimmune responsesbiological chemistrylymphocyte development

Characterization of the Structural Requirements for the Nadase Activity of Bacterial Toll/Il-1R Domains in a Course-Based Undergraduate Research Experience. ImmunoHorizons (2024)

bacterial toll/il-1r domainsmolecular microbiologyimmunologylaboratory investigationmicrobiologybacterianadase activityimmune responsesstructural requirementsbiological chemistryapplied microbiologyinnate immune system

Data From a Recombinant Immunotoxin Against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity. (2023)

immunotoxicologycancer immunotherapyimmunologyimmunotherapycellular therapyallergytoxinsimmunomodulationimmune responseshigh activitya recombinant immunotoxintherapeutic targetsmesotheliomalow off-target toxicityimmunochemistry

Development of an Anti‐Lmp2 Disulfide‐Stabilized Recombinant Immunotoxin Based on Pseudomonas Exotoxin A. The FASEB Journal (2021)

antimicrobial agentsinfectious diseasespathogenic bacteriaimmunologymicrobial toxinsmicrobiologytoxinsimmune responsesimmunity (medicine)antimicrobial compoundsinfection controlmicrobial pathogenesis

The Influence of Furin and the Kdel Receptor on the Efficacy of Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. The FASEB Journal (2021)

antimicrobial susceptibilitytoxinologybacteriaclinical microbiologyrecombinant immunotoxinsinfectious diseasesmycotoxin researchpathogenesistoxinspathogensinfection controlkdel receptorpathogenic bacteriamicrobial toxinsmicrobiologyapplied microbiologymicrobial pathogenesisantimicrobial agentsantimicrobial resistancevirulence factors

An Anti‐Mesothelin Recombinant Immunotoxin Based on Deoxyribonuclease‐I. The FASEB Journal (2020)

immunotoxicologymycotoxin researchimmunologymedicinal researchimmunotherapyanti‐mesothelin recombinant immunotoxintoxinsimmune responses

Developing and Evaluating Recombinant Immunotoxins Against Latent Epstein Barr Virus Infected Cells. The FASEB Journal (2020)

infectious diseasesvaccinesantiviral responsesimmunologyimmunotherapycellular therapyimmune responsesimmunity (medicine)adaptive immune systemlaboratory immunologymedical virologyimmunologic mechanismsevaluating recombinant immunotoxinsclinical immunologyvirus research

Mutations in the Furin Cleavage Site to Improve Cytotoxicity in Anti‐Mesothelin Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. The FASEB Journal (2020)

medical microbiologyimmunotoxicologyantimicrobial agentsinfectious diseasesmycotoxin researchpathogenic bacteriapathogenesisimmunologytoxinologymicrobial toxinsmicrobiologytoxinspathogensvirulence factorsanti‐mesothelin recombinant immunotoxinsimprove cytotoxicityfurin cleavage sitemicrobial pathogenesis

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John Weldon

Associate Professor

Towson University

Affiliations

Jess & Mildred Fisher College of Science & Mathematics

Department of Biological Sciences

John Weldon is currently serving as a Biological Sciences Associate Professor at Towson University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Weldon

Towson University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Faculty Rewards From Course-Based Undergraduate Research Experiences (Cure) in Biochemistry. Journal of Microbiology and Biology Education (2025)

educationstem educationundergraduate researchmentorshiphigher educationmedicinechemistry educationstudent learninghigher education teachingfaculty rewardsfaculty professional development

Intracellular Trafficking of Furin Enhances Cellular Intoxication by Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. Biology Open (2025)

Abstract 1626 Cytotoxic T Lymphocyte-Mediated Killing of Factor VIII-Specific B Lymphocytes Using a Bispecific Immunoconjugate. Journal of Biological Chemistry (2024)

John WeldonMargaret ReganMatthew BonettDavid Scott

bispecific immunoconjugatecell deathimmunologybiochemistrylymphocyte-mediated killingimmune responsesbiological chemistrylymphocyte development

Characterization of the Structural Requirements for the Nadase Activity of Bacterial Toll/Il-1R Domains in a Course-Based Undergraduate Research Experience. ImmunoHorizons (2024)

Data From a Recombinant Immunotoxin Against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity. (2023)

Development of an Anti‐Lmp2 Disulfide‐Stabilized Recombinant Immunotoxin Based on Pseudomonas Exotoxin A. The FASEB Journal (2021)

antimicrobial agentsinfectious diseasespathogenic bacteriaimmunologymicrobial toxinsmicrobiologytoxinsimmune responsesimmunity (medicine)antimicrobial compoundsinfection controlmicrobial pathogenesis

The Influence of Furin and the Kdel Receptor on the Efficacy of Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. The FASEB Journal (2021)

An Anti‐Mesothelin Recombinant Immunotoxin Based on Deoxyribonuclease‐I. The FASEB Journal (2020)

immunotoxicologymycotoxin researchimmunologymedicinal researchimmunotherapyanti‐mesothelin recombinant immunotoxintoxinsimmune responses

Developing and Evaluating Recombinant Immunotoxins Against Latent Epstein Barr Virus Infected Cells. The FASEB Journal (2020)

Mutations in the Furin Cleavage Site to Improve Cytotoxicity in Anti‐Mesothelin Recombinant Immunotoxins Based on Pseudomonas Exotoxin A. The FASEB Journal (2020)

1
2
3
4
10 / page