Faculty

Institution

Unit

Venue

John Tilton

Associate Professor

Case Western Reserve University

Affiliations

School of Medicine

Molecular Biology and Microbiology

Nutrition

John Tilton is currently serving as a Molecular Biology And Microbiology Associate Professor at Case Western Reserve University.

Honors

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Experiences

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Education

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John Tilton

Case Western Reserve University

Associate Professor

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virology immunology hiv virus research infectious diseases immune responses medicine general virology viral pathogenesis virus-host interactions medical virology epidemiology clinical microbiology antiviral therapy gene expression human retrovirus cellular immune responses molecular virology antiviral research t-regulatory cell viral genetics adaptive immune system drug resistance vaccines microbial pathogenesis host response andrology clinical immunology entry inhibitors hiv infection receptors infection control medicinal research pathogen transmission emerging infectious diseases cytokines host factors viral diagnostics viral replication virus transmission extracellular vesicles human immunodeficiency virus experimental medicine applied microbiology antimicrobial agents scientific data venereology experimental biology chronic viral infections arbovirus disease progression allostatic load antibody engineering antiviral responses disease detection innate immune system antimicrobial chemotherapy viral persistence viral evolution rna biology cell binding hiv entry molecular mechanisms diminished proliferation immunologic comparison extracellular loop domains alpha interferon production cytokine secretion antigen load chimpanzee immunization monocyte proinflammatory cytokines primary infection biomedical research biomedical informatics proteomics translational bioinformatics systems biology translational proteomics intracellular protein delivery protein delivery bioinformatics clinical proteomics

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of Individual Viral Particles by Flow Virometry. Viruses (2024)

Caroline O. TablerJohn C. Tilton

virologydermatologyindividual viral particlesflow virometry

Expression of Single Mrna Constructs Encoding Both Crispr-Cas9 Protein and Guide Rnas for Future Gene Therapy Applications. Columbia Undergraduate Science Journal (2024)

Elvis LangJohn TiltonThomas Sweet

gene therapygene expressionguide rnasundergraduate researchsingle mrna constructsgeneticsmolecular biologyrna biologybiological engineeringcrispr

Mechanism and Kinetics of Hiv-1 Protease Activation. Viruses (2024)

Caroline O. TablerJohn C. Tilton

immunologyhivvirus researchantiviral researchvirus-host interactionsviral pathogenesismolecular virologyvirologyinfectious diseases

Premature Activation of the Hiv-1 Protease is Influenced by Polymorphisms in the Hinge Region. Viruses (2024)

Caroline O. TablerSarah J. WegmanNajwa AlhusainiNicole F. LeeJohn C. Tilton

immunologyhivdermatologyvirus researchmicrobial pathogenesisvirus-host interactionsgeneral virologyviral pathogenesisvirologyviral evolutionhinge regioninfectious diseasesviral replicationvirus transmissionpremature activation

The Hiv-1 Viral Protease is Activated During Assembly and Budding Prior to Particle Release. Journal of Virology (2022)

Caroline O. TablerSarah J. WegmanJiji ChenHari ShroffNajwa AlhusainiJohn C. Tilton

immunologyvirologyhiv

Covid-19 and Cardiovascular Disease. Circulation Research (2021)

Mina K. ChungDavid A. ZidarMichael R. BristowScott J. CameronTimothy ChanClifford V. HardingDeborah H. KwonTamanna SinghJohn C. TiltonEmily J. TsaiNathan R. TuckerJohn BarnardJoseph Loscalzo

public healthcardiologymedicinecovid-19epidemiologycardiovascular disease

Extracellular Vesicles as Carriers of Viruses. ExRNA (2021)

Zach TroyerJohn C. Tilton

virus-host interactionsvenereologyextracellular vesiclesvirologyvirus transmissionmicrobiology

Extracellular Vesicles Carry Sars‐Cov‐2 Spike Protein and Serve as Decoys for Neutralizing Antibodies. Journal of Extracellular Vesicles (2021)

Zach TroyerNajwa AlhusainiCaroline O. TablerThomas SweetKarina Inacio Ladislau de CarvalhoDaniela M. SchlatzerLenore CariasChristopher L. KingKenneth MatreyekJohn C. Tilton

immunologyvirus researchsars-cov-2extracellular vesiclesvirologyantibody engineeringmicrobiologycell biology

The Nih Somatic Cell Genome Editing Program. Nature (2021)

Krishanu SahaErik J. SontheimerP. J. BrooksMelinda R. DwinellCharles A. GersbachDavid R. LiuStephen A. MurrayShengdar Q. TsaiRoss C. WilsonDaniel G. AndersonAravind AsokanJillian F. BanfieldKrystof S. BankiewiczGang BaoJeff W. M. BulteNenad BursacJarryd M. CampbellDaniel F. CarlsonElliot L. ChaikofZheng-Yi ChenR. Holland ChengKarl J. ClarkDavid T. CurielJames E. DahlmanBenjamin E. DevermanMary E. DickinsonJennifer A. DoudnaStephen C. EkkerMarina E. EmborgGuoping FengBenjamin S. FreedmanDavid M. GammGuangping GaoIonita C. GhiranPeter M. GlazerShaoqin GongJason D. HeaneyJon D. HenneboldJohn T. HinsonAnastasia KhvorovaSamira KianiWilliam R. LagorKit S. LamKam W. LeongJon E. LevineJennifer A. LewisCathleen M. LutzDanith H. LySamantha MaraghPaul B. McCrayTodd C. McDevittOleg MirochnitchenkoRyuji MorizaneNiren MurthyRandall S. PratherJohn A. RonaldSubhojit RoySushmita RoyVenkata SabbisettiW. Mark SaltzmanPhilip J. SantangeloDavid J. SegalMary ShimoyamaMelissa C. SkalaAlice F. TarantalJohn C. TiltonGeorge A. TruskeyMoriel VandsburgerJonathan K. WattsKevin D. WellsScot A. WolfeQiaobing XuWen XueGuohua YiJiangbing Zhou

biomolecular engineeringbiological engineeringbiomedical engineeringgenome editing

Nanoscale Flow Cytometry Reveals Interpatient Variability in Hiv Protease Activity That Correlates With Viral Infectivity and Identifies Drug-Resistant Viruses. Scientific Reports (2020)

Michał M. BonarCaroline O. TablerAiman A. HaqqaniLauren E. LapointeJake A. GaliatsosSamira Joussef-PiñaMiguel E. Quiñones-MateuJohn C. Tilton

immunologyhivpharmacologynanomedicinevirus-host interactionsviral persistenceclinical microbiologyviral infectivityviral pathogenesishiv protease activitydrug resistancescientific datavirologyglobal health

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John Tilton

Associate Professor

Case Western Reserve University

Affiliations

School of Medicine

Molecular Biology and Microbiology

Nutrition

John Tilton is currently serving as a Molecular Biology And Microbiology Associate Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Tilton

Case Western Reserve University

Associate Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of Individual Viral Particles by Flow Virometry. Viruses (2024)

Caroline O. TablerJohn C. Tilton

virologydermatologyindividual viral particlesflow virometry

Expression of Single Mrna Constructs Encoding Both Crispr-Cas9 Protein and Guide Rnas for Future Gene Therapy Applications. Columbia Undergraduate Science Journal (2024)

Elvis LangJohn TiltonThomas Sweet

gene therapygene expressionguide rnasundergraduate researchsingle mrna constructsgeneticsmolecular biologyrna biologybiological engineeringcrispr

Mechanism and Kinetics of Hiv-1 Protease Activation. Viruses (2024)

Caroline O. TablerJohn C. Tilton

immunologyhivvirus researchantiviral researchvirus-host interactionsviral pathogenesismolecular virologyvirologyinfectious diseases

Premature Activation of the Hiv-1 Protease is Influenced by Polymorphisms in the Hinge Region. Viruses (2024)

Caroline O. TablerSarah J. WegmanNajwa AlhusainiNicole F. LeeJohn C. Tilton

The Hiv-1 Viral Protease is Activated During Assembly and Budding Prior to Particle Release. Journal of Virology (2022)

Caroline O. TablerSarah J. WegmanJiji ChenHari ShroffNajwa AlhusainiJohn C. Tilton

immunologyvirologyhiv

Covid-19 and Cardiovascular Disease. Circulation Research (2021)

Mina K. ChungDavid A. ZidarMichael R. BristowScott J. CameronTimothy ChanClifford V. HardingDeborah H. KwonTamanna SinghJohn C. TiltonEmily J. TsaiNathan R. TuckerJohn BarnardJoseph Loscalzo

public healthcardiologymedicinecovid-19epidemiologycardiovascular disease

Extracellular Vesicles as Carriers of Viruses. ExRNA (2021)

Zach TroyerJohn C. Tilton

virus-host interactionsvenereologyextracellular vesiclesvirologyvirus transmissionmicrobiology

Extracellular Vesicles Carry Sars‐Cov‐2 Spike Protein and Serve as Decoys for Neutralizing Antibodies. Journal of Extracellular Vesicles (2021)

Zach TroyerNajwa AlhusainiCaroline O. TablerThomas SweetKarina Inacio Ladislau de CarvalhoDaniela M. SchlatzerLenore CariasChristopher L. KingKenneth MatreyekJohn C. Tilton

immunologyvirus researchsars-cov-2extracellular vesiclesvirologyantibody engineeringmicrobiologycell biology

The Nih Somatic Cell Genome Editing Program. Nature (2021)

biomolecular engineeringbiological engineeringbiomedical engineeringgenome editing

Nanoscale Flow Cytometry Reveals Interpatient Variability in Hiv Protease Activity That Correlates With Viral Infectivity and Identifies Drug-Resistant Viruses. Scientific Reports (2020)

Michał M. BonarCaroline O. TablerAiman A. HaqqaniLauren E. LapointeJake A. GaliatsosSamira Joussef-PiñaMiguel E. Quiñones-MateuJohn C. Tilton

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hiv eradication

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cellular therapy

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