Faculty

Institution

Unit

Venue

John Marshall

Professor of Medical Science

Brown University

Affiliations

Division of Biology and Medicine

Molecular Biology, Cell Biology, and Biochemistry

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

John Marshall is currently serving as a Division Of Biology And Medicine Professor of Medical Science at Brown University.

Honors

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Experiences

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Education

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John Marshall

Brown University

Professor of Medical Science

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neuroscience pharmacology neurology cell signaling signal transduction molecular biology membrane biology neurophysiology gene expression protein science molecular neuroscience receptors molecular physiology cellular neurobiology cognitive neuroscience biological chemistry molecular neurobiology signaling pathways cell regulation neurochemistry cellular physiology medicinal research neuronal survival cell death molecular regulation neurotransmission peptide science cellular biology protein function apoptosis angelman syndrome peptidomimetic inhibitors peptides stem cell research biochemical sciences mammalian biology experimental medicine liver physiology enzyme inhibition brain science clinical neuroscience neural science receptor (biochemistry) retina gene regulatory networks cutaneous biology kainate receptors cyclic peptide redox biology fish biology hyperpolarization (biology) secretory pathway brain circuitry oncogenic agent cell trafficking protein phosphorylation protein transport brain mechanisms functional regulation protein expression dopamine neuroprotection mitochondrial function enzyme specificity functional recovery genomic clones rectifier potassium channels rat brain incomplete desensitization protective effects neurotoxicity-induced apoptosis unknown secretory pathway nmda receptors cask mediate sorting akt-dependent potentiation multiple trafficking signals glutamate receptors neuropsychopharmacology neurogenetics signal transduction pathways degenerative pathology molecular neurodegeneration seizure disorders

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Trkb-Mtor Peptidomimetic Promotes Axon Regeneration and Restores Walking After Adult Spinal Cord Injury. (2024)

Chao-wen BaiChang SheHua-jian ShanJin-long ChaiChen-yang XuJohn MarshallCong CaoXiaozhong Zhou

spinal traumaregeneration (biology)neurorehabilitationneurodegenerative diseasesneuroregenerationspinal cord injuryneuroscienceneurological rehabilitationspinal cordphysiologytrkb-mtor peptidomimetic promotesneuroanatomyrehabilitationbrain injury

Interlinked Destinies: How Ubiquitin-Proteasome and Autophagy Systems Underpin Neurocognitive Outcomes. Experimental Neurology (2024)

Xin YangJulia DuckhornJohn MarshallYu-Wen Alvin Huang

neurologyinterlinked destiniescognitive neuroscienceneuroscience

Peptidomimetic Inhibitors Targeting Trkb/Psd-95 Signaling Improves Cognition and Seizure Outcomes in an Angelman Syndrome Mouse Model. Neuropsychopharmacology (2024)

Emily Z. HuieXin YangMengia S. Rioult-PedottiKyle TranEmma R. MonsenKim HansenMichelle A. EricksonMandar NaikAnna Y. YotovaWilliam A. BanksYu-Wen Alvin HuangJill L. SilvermanJohn Marshall

epilepsyneuropharmacologyseizure outcomesmedicinal researchneuroscienceexperimental medicinepeptidomimetic inhibitorspharmacologyneurologydrug discoverycognitive neuroscience

Syn3, a Newly Developed Cyclic Peptide and Bdnf Signaling Enhancer, Ameliorates Retinal Ganglion Cell Degeneration in Diabetic Retinopathy. Protein & Cell (2024)

Ke-ran LiMeng-Jia HuanJin YaoJia-jun LiYuan CaoSuyu WangMandar T NaikYuan FangJohn MarshallChang-gong LanCong Cao

cell biologycell signalingprotein scienceneuroscienceophthalmologypeptide sciencemolecular physiologycyclic peptideprotein geneticspeptidesprotein biosynthesisretinacell and molecular biologyprotein functionstructural biologydiabetic retinopathyprotein chemistrysignal transductionprotein engineeringcellular physiology

Targeting the Postsynaptic Scaffolding Protein Psd-95 Enhances Bdnf Signaling to Mitigate Depression-Like Behaviors in Mice. Science Signaling (2024)

Xin ShiXiao-zhong ZhouGang ChenWei-feng LuoChengyu ZhouTian-ju HeMandar T. NaikQin JiangJohn MarshallCong Cao

clinical neuroscienceaffective neuroscienceneurosciencebehavioral sciencesbehavioral neurosciencesignal transductionneurologycognitive neurosciencedepression-like behaviors

Targeting Trkb–Psd-95 Coupling to Mitigate Neurological Disorders. Neural Regeneration Research (2024)

Xin YangYu-Wen Alvin HuangJohn Marshall

neurologytherapeutic targetsneuroscience

A Psd-95 Peptidomimetic Mitigates Neurological Deficits in a Mouse Model of Angelman Syndrome. Progress in Neurobiology (2023)

Kara A. LauXin YangMengia S. Rioult-PedottiStephen TangMark ApplemanJianan ZhangYuyang TianCaitlin MarinoMudi YaoQin JiangAyumi C. TsudaYu-Wen Alvin HuangCong CaoJohn Marshall

geneticsangelman syndromehuman geneticsneuroscienceneurologymouse model

Author Response for"Structure‐Based Design of Peptidomimetic Inhibitors of Scp Psd /Scp ‐95 With Improved Affinity for the Scp Pdz3 /Scp Domain". (2023)

None Mandar T. NaikNone Nandita NaikNone Tony HuNone Szu‐Huan WangNone John Marshall

structure-based designauthor responsepeptidomimetic inhibitorskey sitepharmacologydrug discovery

Structure‐Based Design of Peptidomimetic Inhibitors of Psd ‐95 With Improved Affinity for the Pdz3 Domain. FEBS Letters (2023)

Mandar T. NaikNandita NaikTony HuSzu‐Huan WangJohn Marshall

structure-based designneurosciencepeptidomimetic inhibitorspharmacologyrational drug designdrug discovery

Structure-Based Development of New Cyclic Compounds Targeting Psd-95 Pdz3 Domain. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Mandar T. NaikNandita NaikTony HuSzu-Huan WangJohn Marshall

structure-based developmentgeneticsstructural biologyneuroscience

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John Marshall

Professor of Medical Science

Brown University

Affiliations

Division of Biology and Medicine

Molecular Biology, Cell Biology, and Biochemistry

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

John Marshall is currently serving as a Division Of Biology And Medicine Professor of Medical Science at Brown University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Marshall

Brown University

Professor of Medical Science

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Trkb-Mtor Peptidomimetic Promotes Axon Regeneration and Restores Walking After Adult Spinal Cord Injury. (2024)

Chao-wen BaiChang SheHua-jian ShanJin-long ChaiChen-yang XuJohn MarshallCong CaoXiaozhong Zhou

Interlinked Destinies: How Ubiquitin-Proteasome and Autophagy Systems Underpin Neurocognitive Outcomes. Experimental Neurology (2024)

Xin YangJulia DuckhornJohn MarshallYu-Wen Alvin Huang

neurologyinterlinked destiniescognitive neuroscienceneuroscience

Peptidomimetic Inhibitors Targeting Trkb/Psd-95 Signaling Improves Cognition and Seizure Outcomes in an Angelman Syndrome Mouse Model. Neuropsychopharmacology (2024)

Emily Z. HuieXin YangMengia S. Rioult-PedottiKyle TranEmma R. MonsenKim HansenMichelle A. EricksonMandar NaikAnna Y. YotovaWilliam A. BanksYu-Wen Alvin HuangJill L. SilvermanJohn Marshall

epilepsyneuropharmacologyseizure outcomesmedicinal researchneuroscienceexperimental medicinepeptidomimetic inhibitorspharmacologyneurologydrug discoverycognitive neuroscience

Syn3, a Newly Developed Cyclic Peptide and Bdnf Signaling Enhancer, Ameliorates Retinal Ganglion Cell Degeneration in Diabetic Retinopathy. Protein & Cell (2024)

Ke-ran LiMeng-Jia HuanJin YaoJia-jun LiYuan CaoSuyu WangMandar T NaikYuan FangJohn MarshallChang-gong LanCong Cao

Targeting the Postsynaptic Scaffolding Protein Psd-95 Enhances Bdnf Signaling to Mitigate Depression-Like Behaviors in Mice. Science Signaling (2024)

Xin ShiXiao-zhong ZhouGang ChenWei-feng LuoChengyu ZhouTian-ju HeMandar T. NaikQin JiangJohn MarshallCong Cao

clinical neuroscienceaffective neuroscienceneurosciencebehavioral sciencesbehavioral neurosciencesignal transductionneurologycognitive neurosciencedepression-like behaviors

Targeting Trkb–Psd-95 Coupling to Mitigate Neurological Disorders. Neural Regeneration Research (2024)

Xin YangYu-Wen Alvin HuangJohn Marshall

neurologytherapeutic targetsneuroscience

A Psd-95 Peptidomimetic Mitigates Neurological Deficits in a Mouse Model of Angelman Syndrome. Progress in Neurobiology (2023)

Kara A. LauXin YangMengia S. Rioult-PedottiStephen TangMark ApplemanJianan ZhangYuyang TianCaitlin MarinoMudi YaoQin JiangAyumi C. TsudaYu-Wen Alvin HuangCong CaoJohn Marshall

geneticsangelman syndromehuman geneticsneuroscienceneurologymouse model

Author Response for"Structure‐Based Design of Peptidomimetic Inhibitors of Scp Psd /Scp ‐95 With Improved Affinity for the Scp Pdz3 /Scp Domain". (2023)

None Mandar T. NaikNone Nandita NaikNone Tony HuNone Szu‐Huan WangNone John Marshall

structure-based designauthor responsepeptidomimetic inhibitorskey sitepharmacologydrug discovery

Structure‐Based Design of Peptidomimetic Inhibitors of Psd ‐95 With Improved Affinity for the Pdz3 Domain. FEBS Letters (2023)

Mandar T. NaikNandita NaikTony HuSzu‐Huan WangJohn Marshall

structure-based designneurosciencepeptidomimetic inhibitorspharmacologyrational drug designdrug discovery

Structure-Based Development of New Cyclic Compounds Targeting Psd-95 Pdz3 Domain. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Mandar T. NaikNandita NaikTony HuSzu-Huan WangJohn Marshall

structure-based developmentgeneticsstructural biologyneuroscience

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