Faculty

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Unit

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John Krstenansky

Keck Graduate Institute

Affiliations

Department Of Pharmacy

Keck Graduate Institute

School of Medicine

NoneJohn Krstenansky is currently serving as a Pharmacy faculty at Keck Graduate Institute.

Honors

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Experiences

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Education

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John Krstenansky

Keck Graduate Institute

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pharmacology drug discovery molecular pharmacology chemical synthesis pharmacological research biochemistry therapeutic targets pharmacotherapy organic chemistry frontier mechanisms of action medicinal chemistry small molecules pharmaceutics medicinal research chemical sciences natural product research organic process research sustainable chemistry pharmaceutical sciences sustainable synthesis solvent extraction system pharmacology enantioselective synthesis stereoselective synthesis ionic liquid immunology molecular biology enzymes bioorganic chemistry enzyme inhibition medical virology virus research neuropsychopharmacology peptides future medicinal chemistry applied pharmacology tumor targeting drug targeting cancer-associated virus viral oncology experimental pharmacology drug development peptide therapeutics deep eutectic solvents pharmacological agents pharmaceutical chemistry nicotine tobacco policy tobacco use drug targets receptor (biochemistry) molecular pain asymmetric catalysis green methodology green analytical method small molecule inhibitors promising anti-cancer target potential binding pocket pharmacological characterization ethylenediamine synthetic opioids conventional solvent novel mixed μ‐/κ‐opioid vitro pharmacology vivo activity u‐47700 analogs synthetic opioid ah‐7921 diastereofacial selectivity chiral cubane analogs organic solvents ionic liquid method

Notable Scholarly Works

Notable Federal Grants

Collaborators

Simplified Nomenclature and Projection Diagrams of Chiral Cubane Analogs. ACS Omega (2024)

symmetryenantioselective synthesiscategory theorystructural chemistrychiral cubane analogsmathematicsstereoselective synthesis

Diastereofacial Selectivity of α-Aminonitrile Formation From Substituted Cyclohexanones. Tetrahedron Letters (2023)

organic chemistryenantioselective synthesisasymmetric catalysisdiastereofacial selectivitychemical scienceschemistryorganic chemistry frontierchemical synthesisstereoselective synthesis

Synthesis, Structure, in Vitro Pharmacology, and in Vivo Activity of Trans ‐3, 4‐Dichloro‐ N ‐[[1‐(Dimethylamino)‐4‐Phenylcyclohexyl]Methyl]‐Benzamide ( Ap01 ; 4‐Phenyl‐Ah ‐7921), a Novel Mixed μ‐/κ‐Opioid. Journal of Forensic Sciences (2023)

medicinal chemistrypharmaceutical chemistrymechanisms of actiondrug metabolismmolecular pharmacologyapplied pharmacologyvivo activitypharmaceutical sciencesbiochemistryvitro pharmacologyfuture medicinal chemistrychemical synthesisnovel mixed μ‐/κ‐opioidpharmacological researchpharmacologysystem pharmacologypharmacotherapydrug discoverypharmacological agentspharmaceutics

ACE2: S1 Rbd Interaction-Targeted Peptides and Small Molecules as Potential Covid-19 Therapeutics. Advances in Pharmacological and Pharmaceutical Sciences (2021)

Lennox ChitsikeJohn KrstenanskyPenelope J. Duerksen-Hughes

medicinepharmacologypeptidescovid-19pharmaceutical sciencespharmacotherapymolecular pharmacologytherapeutic targetsdrug discoverymedicinal researchinfectious diseasespeptide therapeuticsdrug deliverydrug developmentpharmacological researchpharmaceutics

Identification of Potential Binding Pocket on Viral Oncoprotein Hpv16 E6: A Promising Anti-Cancer Target for Small Molecule Drug Discovery. BMC Molecular and Cell Biology (2019)

virus researchpotential binding pocketsmall moleculesmedical virologypromising anti-cancer targettherapeutic targetsbiomolecular engineeringdrug discoverymolecular biologycancer-associated virusviral oncology

Synthesis and Pharmacological Characterization of Ethylenediamine Synthetic Opioids in Human μ‐Opiate Receptor 1 (Oprm1) Expressing Cells. Pharmacology Research & Perspectives (2019)

receptorsneuropsychopharmacologypharmacologymechanisms of actionpharmacotherapymolecular pharmacologyneuropharmacologyethylenediamine synthetic opioidspharmacological characterizationexperimental pharmacologypharmacological researchbiochemistry

Assessing the Activity of Synthetic Opioid Ah‐7921 and U‐47700 Analogs in Cloned Human Mu‐Opioid Receptor Expressing Fibrosarcoma Ht‐1080 Cells. The FASEB Journal (2018)

receptorsdrug targetspharmacologymolecular painmechanisms of actionsystem pharmacologymolecular pharmacologytherapeutic targetsreceptor (biochemistry)synthetic opioid ah‐7921drug discoverymedicinal researchmolecular medicineu‐47700 analogspharmacological researchbiochemistrycell biology

Green Chemistry: Comparison of Ionic Liquid vs Conventional Solvent for Indole Alkylation. American Journal of Undergraduate Research (2016)

organic chemistryionic liquidsustainable chemistrychemical engineeringcatalysisconventional solventsolvent extractionorganic synthesisgreen chemistrychemical scienceschemistrydeep eutectic solventsorganic chemistry frontiernatural product researchchemical synthesisorganic process researchsustainable synthesis

Volume 13, Issue 4. American Journal of Undergraduate Research (2016)

Kestutis BendinskasAnthony ContentoRose ThroopDaniel LairdBonita GrahamDean CrawfordLisa SeppiShashi KanburAileen BaileyPamela KerriganJorge RodriguezKevin DaimiJohn JungckIsabelle BichindaritzDavid DunnPoongodi Geetha-LoganathanPeter NewellWilliam BromerJulien BachelierAlfredo CastroCharles KrileyDouglas MulfordMark BenvenutoJennifer GeromettaDele OluwadeAlexander SoudackovElizabeth SchmittMarcia BurrellAndrew GavrinMichael OmidioraEileen CashmanHaoyu WangLarry DavisRichard WeyhingMurat YasarLorrie ClemoDavid SenchinaDouglas GuerraJohn EmertJeffrey BoatsJ PhillipsChristopher BaltusMark BakerJoan NewellSteven SkubisJuliet ForshawGary BakerPamela Scott-JohnsonAmy OvermanDean DohrmanKim TilleryMark EckerJonathan RedricoJohn KrstenanskyChristiana StandlerGary OversonCody BlackGuizella RocabadoBruce HowardAnca RǎdulescuJoanna HerronMathew NybergBrian DraegerBrian WeeklyMichael Love

organic chemistryionic liquid methodionic liquidsustainable chemistrychemical engineeringsolvent extractionorganic synthesisgreen chemistrychemistrygreen analytical methodorganic solventsorganic chemistry frontiernatural product researchchemical synthesisgreen methodologyorganic process researchsustainable synthesis

Analysis of the Smoke of Cigarettes Containing Salvia Divinorum. Journal of Analytical Toxicology (2014)

tobacco policynatural productsnicotineaddictiontoxicologyaddictive behaviorstobacco usetobacco controlregulatory toxicology

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John Krstenansky

Keck Graduate Institute

Affiliations

Department Of Pharmacy

Keck Graduate Institute

School of Medicine

NoneJohn Krstenansky is currently serving as a Pharmacy faculty at Keck Graduate Institute.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Krstenansky

Keck Graduate Institute

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Simplified Nomenclature and Projection Diagrams of Chiral Cubane Analogs. ACS Omega (2024)

symmetryenantioselective synthesiscategory theorystructural chemistrychiral cubane analogsmathematicsstereoselective synthesis

Diastereofacial Selectivity of α-Aminonitrile Formation From Substituted Cyclohexanones. Tetrahedron Letters (2023)

organic chemistryenantioselective synthesisasymmetric catalysisdiastereofacial selectivitychemical scienceschemistryorganic chemistry frontierchemical synthesisstereoselective synthesis

ACE2: S1 Rbd Interaction-Targeted Peptides and Small Molecules as Potential Covid-19 Therapeutics. Advances in Pharmacological and Pharmaceutical Sciences (2021)

Lennox ChitsikeJohn KrstenanskyPenelope J. Duerksen-Hughes

Identification of Potential Binding Pocket on Viral Oncoprotein Hpv16 E6: A Promising Anti-Cancer Target for Small Molecule Drug Discovery. BMC Molecular and Cell Biology (2019)

Synthesis and Pharmacological Characterization of Ethylenediamine Synthetic Opioids in Human μ‐Opiate Receptor 1 (Oprm1) Expressing Cells. Pharmacology Research & Perspectives (2019)

Assessing the Activity of Synthetic Opioid Ah‐7921 and U‐47700 Analogs in Cloned Human Mu‐Opioid Receptor Expressing Fibrosarcoma Ht‐1080 Cells. The FASEB Journal (2018)

Green Chemistry: Comparison of Ionic Liquid vs Conventional Solvent for Indole Alkylation. American Journal of Undergraduate Research (2016)

Volume 13, Issue 4. American Journal of Undergraduate Research (2016)

Analysis of the Smoke of Cigarettes Containing Salvia Divinorum. Journal of Analytical Toxicology (2014)

tobacco policynatural productsnicotineaddictiontoxicologyaddictive behaviorstobacco usetobacco controlregulatory toxicology

1
2
10 / page