Faculty

Institution

Unit

Venue

John Kenneth Cowell

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Pathology

John Kenneth Cowell is currently serving as a Pathology Professor at Augusta University.

Honors

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Experiences

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Education

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John Kenneth Cowell

Augusta University

Professor

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genetics cancer biology cancer genetics cancer research oncology tumor biology molecular biology gene expression cancer genomics medicinal research oncogenes cell biology genomics cytogenetics neurology human genetics molecular cancer leukemia genome biology hematology medical genetics cancer care hematological malignancies brain tumor research cell regulation neuro-oncology tumor targeting cancer treatment mammalian biology cellular therapy tumor suppressors cell death cancer cells enzyme inhibition lymphoid neoplasia chromosome biology protein science cancer growth experimental medicine gene function cell motility anti-cancer agents biological chemistry cancer imaging gene regulation experimental neuropathology colorectal cancer fibroblast growth factors apoptosis comparative genomics molecular pathology protein genetics molecular regulation cell lineage myeloid neoplasia mouse model breast cancer cells prostate cancer cells clinical pathology protein function genome analysis brain pathology microarray data analysis multiple myeloma copy number abnormalities atypical myeloproliferative disorder myeloproliferative disease glioblastoma multiforme novel gene telomerase rna microsatellite instability lamellipodia formation lymphoid malignancies pediatric medulloblastomas spectral karyotyping chromosome translocation protein chemistry proteomics animal modeling systems biology bioinformatics database genetic basis cancer letter molecular informatics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 187: Macrophage Instead of Leukemia Cell Expressed Pd-L1 Drives T Cell Exhaustion and Immune Evasion of Bcrabl1 Chronic Myeloid Leukemia. Cancer Research (2024)

Xiaocui LuHui FangXuexiu FangAtsuko MatsunagaKebin LiuJorge CortesJohn K. CowellTianxiang Hu

immunologymedicineleukemialeukemia cellcancer researchcancer immunotherapyimmune evasiononcologytherapeutic efficacycancer biologyhost response

Leukemia Associated Macrophages and Neutrophils Contribute to Immune Suppression Through Pd-L1 and Arginase in Bcr-Abl1 Chronic Myeloid Leukemia. Blood (2024)

Chang LiuXiaocui LuHui FangJohn Kenneth CowellTianxiang Hu

hematological malignanciescell deathmyeloid neoplasiaautoimmune diseasesbone marrow transplantationmalignant blood disordersinfectious diseasesautoimmunitypathologyhematologythrombosischronic inflammationimmune responsesinflammationleukemiaimmune dysregulationimmune suppressionimmunologyoncogenes

Single-Cell Analysis Defines Highly Specific Leukemia-Induced Neutrophils and Links Mmp8 Expression to Recruitment of Tumor Associated Neutrophils During Fgfr1 Driven Leukemogenesis. Experimental Hematology and Oncology (2024)

Tianxiang HuBo ChengAtsuko MatsunagaTing ZhangXiaocui LuHui FangStephanie F. MoriXuexiu FangGavin WangHongyan XuHuidong ShiJohn K. Cowell

immunologyhematological malignanciesmedicineleukemiahematologycancer researchsingle-cell analysisoncologycancer biologytumor biology

Abstract 1353: Cd71 and Cd117 Identifies an Early Cancer Associated Macrophage Progenitor Population in Leukemic Mouse Bone Marrow. Cancer Research (2023)

Xiaocui LuTing ZhangAtsuko MatsunagaXuexiu FangStephanie F. MoriJohn CowellTianxiang Hu

immunologycarcinogenesisdermatologyleukemiahematological malignanciescancer carecancer geneticshematologymacrophage progenitor populationcancer researchcancer genomicscancer immunotherapyoncologymedicinal researchcancer riskcancer biologyhealth sciencesearly cancer

Abstract 657: Irak1 Regulated Inflammatory Signal From the Leukemia Cells Modulates Tumor Microenvironment and Promote Leukemogenesis. Cancer Research (2023)

Ting ZhangXiaocui LuAtsuko MatsunagaXuexiu FangStephanie Fay MoriJohn CowellTianxiang Hu

immunologyhematological malignanciesdermatologymedicineleukemialeukemia cellscell regulationinflammatory signalcancer researchoncologymedicinal researchtumor microenvironmentcancer biologytumor biologyinflammation

Data From Mir-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the I Bcl2L11 /I and I Bax /I Proapoptotic Genes. (2023)

Tianxiang HuYating ChongSumin LuRebecca WangHaiyan QinJeane SilvaEiko KitamuraChang-Sheng ChangLesleyAnn HawthornJohn K. Cowell

gene expressionleukemiacancer geneticshematologycancer researchlymphoid neoplasiageneticsmolecular biologystem cellsdevelopmental biologymedical geneticscancer biologylymphocyte development

Data From Targeting the Wasf3–Cyfip1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion. (2023)

Yong TengAbdulaziz BahassanDayong DongLaura E. HanoldXiaoou RenEileen J. KennedyJohn K. Cowell

immunologytumor targetingpharmacologypeptidescancer researchprotein bioinformaticsanti-cancer agentsoncologycancer biologycell biology

Data From the Wasf3–Nckap1–Cyfip1 Complex is Essential for Breast Cancer Metastasis. (2023)

Yong TengHaiyan QinAbdulaziz BahassanN. George BendzunasEileen J. KennedyJohn K. Cowell

cancer geneticscancer researchgeneticscancer genomicscancer immunotherapybreast cancermolecular biologyoncologycancer biologytumor biologyhealth sciencesbreast cancer metastasisbreast oncology

Supplementary Figure 1 From Src Activation Plays an Important Key Role in Lymphomagenesis Induced by Fgfr1 Fusion Kinases. (2023)

Mingqiang RenHaiyan QinRuizhe RenJosephine TidwellJohn K. Cowell

immunologygene expressionpharmacologymetastasiscancer geneticssrc activationintermediate hostgeneticstranscription factorsmolecular and cellular biologymammalian biologycancer genomicsoncogenesmedicinal researchcatalyst activationcancer biologytumor biology

Supplementary Figure 8 From the Wasf3–Nckap1–Cyfip1 Complex is Essential for Breast Cancer Metastasis. (2023)

Yong TengHaiyan QinAbdulaziz BahassanN. George BendzunasEileen J. KennedyJohn K. Cowell

metastasiscancer geneticscancer researchbreast cancer metastasisbreast cancercancer biologybiochemistry

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John Kenneth Cowell

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Pathology

John Kenneth Cowell is currently serving as a Pathology Professor at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Kenneth Cowell

Augusta University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 187: Macrophage Instead of Leukemia Cell Expressed Pd-L1 Drives T Cell Exhaustion and Immune Evasion of Bcrabl1 Chronic Myeloid Leukemia. Cancer Research (2024)

Xiaocui LuHui FangXuexiu FangAtsuko MatsunagaKebin LiuJorge CortesJohn K. CowellTianxiang Hu

immunologymedicineleukemialeukemia cellcancer researchcancer immunotherapyimmune evasiononcologytherapeutic efficacycancer biologyhost response

Leukemia Associated Macrophages and Neutrophils Contribute to Immune Suppression Through Pd-L1 and Arginase in Bcr-Abl1 Chronic Myeloid Leukemia. Blood (2024)

Chang LiuXiaocui LuHui FangJohn Kenneth CowellTianxiang Hu

Tianxiang HuBo ChengAtsuko MatsunagaTing ZhangXiaocui LuHui FangStephanie F. MoriXuexiu FangGavin WangHongyan XuHuidong ShiJohn K. Cowell

immunologyhematological malignanciesmedicineleukemiahematologycancer researchsingle-cell analysisoncologycancer biologytumor biology

Abstract 1353: Cd71 and Cd117 Identifies an Early Cancer Associated Macrophage Progenitor Population in Leukemic Mouse Bone Marrow. Cancer Research (2023)

Xiaocui LuTing ZhangAtsuko MatsunagaXuexiu FangStephanie F. MoriJohn CowellTianxiang Hu

Abstract 657: Irak1 Regulated Inflammatory Signal From the Leukemia Cells Modulates Tumor Microenvironment and Promote Leukemogenesis. Cancer Research (2023)

Ting ZhangXiaocui LuAtsuko MatsunagaXuexiu FangStephanie Fay MoriJohn CowellTianxiang Hu

Data From Mir-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the I Bcl2L11 /I and I Bax /I Proapoptotic Genes. (2023)

Tianxiang HuYating ChongSumin LuRebecca WangHaiyan QinJeane SilvaEiko KitamuraChang-Sheng ChangLesleyAnn HawthornJohn K. Cowell

gene expressionleukemiacancer geneticshematologycancer researchlymphoid neoplasiageneticsmolecular biologystem cellsdevelopmental biologymedical geneticscancer biologylymphocyte development

Data From Targeting the Wasf3–Cyfip1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion. (2023)

Yong TengAbdulaziz BahassanDayong DongLaura E. HanoldXiaoou RenEileen J. KennedyJohn K. Cowell

immunologytumor targetingpharmacologypeptidescancer researchprotein bioinformaticsanti-cancer agentsoncologycancer biologycell biology

Data From the Wasf3–Nckap1–Cyfip1 Complex is Essential for Breast Cancer Metastasis. (2023)

Yong TengHaiyan QinAbdulaziz BahassanN. George BendzunasEileen J. KennedyJohn K. Cowell

cancer geneticscancer researchgeneticscancer genomicscancer immunotherapybreast cancermolecular biologyoncologycancer biologytumor biologyhealth sciencesbreast cancer metastasisbreast oncology

Supplementary Figure 1 From Src Activation Plays an Important Key Role in Lymphomagenesis Induced by Fgfr1 Fusion Kinases. (2023)

Mingqiang RenHaiyan QinRuizhe RenJosephine TidwellJohn K. Cowell

Supplementary Figure 8 From the Wasf3–Nckap1–Cyfip1 Complex is Essential for Breast Cancer Metastasis. (2023)

Yong TengHaiyan QinAbdulaziz BahassanN. George BendzunasEileen J. KennedyJohn K. Cowell

metastasiscancer geneticscancer researchbreast cancer metastasisbreast cancercancer biologybiochemistry

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