Faculty

Institution

Unit

Venue

John Cavanagh

Professor & Chair of Biochemistry /Molecular Biology Associate Dean for Research and Chair of Foundational Sciences

East Carolina University

Affiliations

Brody School of Medicine

Biochemistry and Molecular Biology

John Cavanagh is currently serving as a Biochemistry And Molecular Biology Professor & Chair of Biochemistry /Molecular Biology Associate Dean for Research and Chair of Foundational Sciences at East Carolina University.

Honors

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Experiences

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Education

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John Cavanagh

East Carolina University

Professor & Chair of Biochemistry /Molecular Biology Associate Dean for Research and Chair of Foundational Sciences

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molecular biology structural biology biophysics nuclear magnetic resonance biochemistry protein science microbiology protein structure molecular microbiology clinical microbiology bacillus subtilis structural molecular biology magnetic resonance biofilms bacteriology biomolecular structure applied microbiology nuclear magnetic resonance spectroscopy spectroscopy chemical shift assignments enzymes drug discovery gene expression molecular structure acinetobacter baumannii response regulators structural bioinformatics medical microbiology secondary structure resonance assignments nmr spectroscopy secondary structure prediction molecular science redox biology peptides infection control biochemical sciences structure determination structural genomics microbial physiology biomolecular interactions gene regulation microbial genetics antibiotic resistance sensitivity improvement genome biology structural chemistry environmental microbiology protein nmr conformational studies biochemical interaction benchmark studies protein modeling protein genetics structural composition molecular biotechnology drug targeting drug development conventional antibiotics bacterial biofilms response regulator dna binding dna-binding domain bioresource technology protein structure prediction biomolecular structure prediction molecular immunology molecular recognition immunochemistry chemical biotechnology chemical technology experimental analysis protein function signaling pathways temperature dependence intramolecular dynamics signal transduction pathways biophysical techniques infectious diseases antimicrobial resistance therapeutic intervention antimicrobial agent antibiotic adjuvant

Notable Scholarly Works

Notable Federal Grants

Collaborators

Insights Into Dna-Binding Motifs and Mechanisms of Francisella Tularensis Novicida Two-Component System Response Regulator Proteins Qseb, Kdpe, and Bfpr. Biochemical and Biophysical Research Communications (2024)

Keegan E. GaddyElody M. BenschJohn CavanaghMorgan E. Milton

biophysicsmolecular and cellular biologyprotein sciencecell signalingmolecular microbiologybiochemistrygene regulationmolecular physiologydna-binding motifsbiochemical sciencesmolecular biologybiomolecular interactionsfrancisella tularensisgene expressionbiophysical chemistrymolecular regulationstructural biologyprotein biosynthesis

2-Aminoimidazole Analogs Target Phop Altering Dna Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria. Biochemistry (2022)

Tonya N. ZeczyckiMorgan E. MiltonDavid JungRichele J. ThompsonFelicia E. JaimesAlexander D. HondrosSamantha PalethorpeChristian MelanderJohn Cavanagh

immunologybiochemistrydna binding activitymembrane biologypharmacologygram-negative bacteria

The Biofilm Regulatory Network From Bacillus Subtilis: A Structure-Function Analysis. Journal of Molecular Biology (2022)

Morgan E MiltonJohn Cavanagh

molecular microbiologybiofilmsmicrobiologymolecular biologybacillus subtilissystems biologybiofilm regulatory networkstructure-function analysis

Acinetobacter Baumannii Regulates Its Stress Responses via the Bfmrs Two-Component Regulatory System. Journal of Bacteriology (2021)

Samantha PalethorpeJohn M. FarrowGreg WellsMorgan E. MiltonLuis A. ActisJohn CavanaghEverett C. Pesci

regulationclinical microbiologymedical microbiologyvirologyacinetobacter baumanniiimmunologymicrobial physiologymicrobiologyglobal healthgene regulationstress responsesbacteriology

Structure of the Acinetobacter Baumannii Pmra Receiver Domain and Insights Into Clinical Mutants Affecting Dna Binding and Promoting Colistin Resistance. The Journal of Biochemistry (2021)

Samantha PalethorpeMorgan E MiltonEverett C PesciJohn Cavanagh

bacteriamolecular geneticsclinical mutantsstructural molecular biologygeneticsclinical microbiologyclinical biochemistrymicrobial geneticsdna bindingbiochemistrymicrobiologydrug resistanceprotein structurebacteriologybiochemical geneticsstructural biologyprotein geneticsmolecular microbiologycolistin resistance

Francisella Novicida Two-Component System Response Regulator Bfpr Modulates Iglc Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production. Frontiers in Cellular and Infection Microbiology (2020)

Scott N. DeanMorgan E. MiltonJohn CavanaghMonique L. van Hoek

clinical microbiologymedical microbiologyinfectious diseasesantimicrobial peptide resistancebiofilm productionmolecular microbiologyimmunologymicrobiologyveterinary microbiologyiglc gene expressionapplied microbiologymicrobial pathogenesis

Filling in the Gaps for the Master Regulator of Biofilm Formation in Bacillus Subtilis: A Structural and Biochemical Look at Sinr and Sini. The FASEB Journal (2019)

Morgan Eilise MiltonG. Logan DraughnBenjamin G BobaySean D StoweAndrew L OlsonErik A FeldmannRichele J ThompsonKatherine H MyersMichael T SantoroDaniel B KearnsJohn Cavanagh

master regulatorbiomolecular structurebiofilmsmicrobiologyfacies analysisbiofilm formationbacillus subtilismicrobial ecology

The Solution Structures and Interaction of Sinr and Sini: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus Subtilis. Journal of Molecular Biology (2019)

Morgan E. MiltonG. Logan DraughnBenjamin G. BobaySean D. StoweAndrew L. OlsonErik A. FeldmannRichele J. ThompsonKatherine H. MyersMichael T. SantoroDaniel B. KearnsJohn Cavanagh

solution structuresmaster regulator switchmolecular microbiologybiofilmsmolecular biologybacillus subtilisbiofilm formation

Characterization of the Dna Binding Activity of the Bacterial Response Regulator Bfmr From Acinetobacter Baumannii. F1000Research (2018)

Morgan E. MiltonG. Logan DraughnRichele J. ThompsonJohn Cavanagh

clinical microbiologyacinetobacter baumanniimolecular microbiologyimmunologygenomicsmicrobiologymolecular biologybacteriology

Resensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators.. F1000Research (2018)

Morgan E. MiltonBradley M. MinrovicDanni L. HarrisG. Logan DraughnBrian KangDavid JungCaleb P. LewisRichele J. ThompsonRoberta J. MelanderDaina ZengChristian MelanderJohn Cavanagh

clinical microbiologyantibiotic resistanceantimicrobial resistanceglobal healthdrug resistancepharmacologybacterial response regulatorsmultidrug resistant bacteria

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John Cavanagh

Professor & Chair of Biochemistry /Molecular Biology Associate Dean for Research and Chair of Foundational Sciences

East Carolina University

Affiliations

Brody School of Medicine

Biochemistry and Molecular Biology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Cavanagh

East Carolina University

Professor & Chair of Biochemistry /Molecular Biology Associate Dean for Research and Chair of Foundational Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Keegan E. GaddyElody M. BenschJohn CavanaghMorgan E. Milton

2-Aminoimidazole Analogs Target Phop Altering Dna Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria. Biochemistry (2022)

Tonya N. ZeczyckiMorgan E. MiltonDavid JungRichele J. ThompsonFelicia E. JaimesAlexander D. HondrosSamantha PalethorpeChristian MelanderJohn Cavanagh

immunologybiochemistrydna binding activitymembrane biologypharmacologygram-negative bacteria

The Biofilm Regulatory Network From Bacillus Subtilis: A Structure-Function Analysis. Journal of Molecular Biology (2022)

Morgan E MiltonJohn Cavanagh

molecular microbiologybiofilmsmicrobiologymolecular biologybacillus subtilissystems biologybiofilm regulatory networkstructure-function analysis

Acinetobacter Baumannii Regulates Its Stress Responses via the Bfmrs Two-Component Regulatory System. Journal of Bacteriology (2021)

Samantha PalethorpeJohn M. FarrowGreg WellsMorgan E. MiltonLuis A. ActisJohn CavanaghEverett C. Pesci

regulationclinical microbiologymedical microbiologyvirologyacinetobacter baumanniiimmunologymicrobial physiologymicrobiologyglobal healthgene regulationstress responsesbacteriology

Structure of the Acinetobacter Baumannii Pmra Receiver Domain and Insights Into Clinical Mutants Affecting Dna Binding and Promoting Colistin Resistance. The Journal of Biochemistry (2021)

Samantha PalethorpeMorgan E MiltonEverett C PesciJohn Cavanagh

Scott N. DeanMorgan E. MiltonJohn CavanaghMonique L. van Hoek

Filling in the Gaps for the Master Regulator of Biofilm Formation in Bacillus Subtilis: A Structural and Biochemical Look at Sinr and Sini. The FASEB Journal (2019)

Morgan Eilise MiltonG. Logan DraughnBenjamin G BobaySean D StoweAndrew L OlsonErik A FeldmannRichele J ThompsonKatherine H MyersMichael T SantoroDaniel B KearnsJohn Cavanagh

master regulatorbiomolecular structurebiofilmsmicrobiologyfacies analysisbiofilm formationbacillus subtilismicrobial ecology

Morgan E. MiltonG. Logan DraughnBenjamin G. BobaySean D. StoweAndrew L. OlsonErik A. FeldmannRichele J. ThompsonKatherine H. MyersMichael T. SantoroDaniel B. KearnsJohn Cavanagh

solution structuresmaster regulator switchmolecular microbiologybiofilmsmolecular biologybacillus subtilisbiofilm formation

Characterization of the Dna Binding Activity of the Bacterial Response Regulator Bfmr From Acinetobacter Baumannii. F1000Research (2018)

Morgan E. MiltonG. Logan DraughnRichele J. ThompsonJohn Cavanagh

clinical microbiologyacinetobacter baumanniimolecular microbiologyimmunologygenomicsmicrobiologymolecular biologybacteriology

Resensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators.. F1000Research (2018)

Morgan E. MiltonBradley M. MinrovicDanni L. HarrisG. Logan DraughnBrian KangDavid JungCaleb P. LewisRichele J. ThompsonRoberta J. MelanderDaina ZengChristian MelanderJohn Cavanagh

clinical microbiologyantibiotic resistanceantimicrobial resistanceglobal healthdrug resistancepharmacologybacterial response regulatorsmultidrug resistant bacteria

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2
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5
14
10 / page

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virulence factors

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