João Mamede

João Mamede is an Associate Professor at Rush University, where his research focuses on HIV-1 virology, epitranscriptomics, and neuroinflammation. His recent work includes developing nanopore-based reference epitranscriptomes for HIV-1, characterizing inflammatory responses in microglia-containing cerebral organoids, and investigating how methamphetamine and neuroHIV impair astrocytic potassium channels. He has also explored metabolic pathways governing HIV-1 replication kinetics and advanced quantitative microscopy methods for molecular complex mapping. His publications appear in Nucleic Acids Research, Nature Communications, and mBio, reflecting his contributions to antiviral research and SARS-CoV-2-related virology.