Faculty

Institution

Unit

Venue

James K. Liao

University of Chicago

Affiliations

Medicine, Department of

James K. Liao is currently serving as a Medicine, Department Of MD at University of Chicago.

Honors

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Experiences

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Education

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James K. Liao

University of Chicago

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Notable Scholarly Works

Notable Federal Grants

Collaborators

Induction of Adipocyte Thermogenic Program by Rho-Associated Coiled-Coil Containing Kinase 2. iScience (2026)

bioenergeticssignal transductionmolecular physiologycell signalingmolecular metabolismphysiologymetabolismmolecular and cellular biologycell metabolismenergy metabolismmetabolic regulation

Recurrent Symptomatic Hemorrhage in Cerebral Cavernous Malformations After Discontinuation of Atorvastatin or Placebo. Journal of the American Heart Association (2026)

vascular malformationscardiologycerebral blood flowcerebrovascular diseaseneurologybrain injuryblood vesselsstrokeneuropathologycardiovascular disease

Safety and Efficacy of Atorvastatin for Rebleeding in Cerebral Cavernous Malformations (at Cash Epoc): A Phase 1/2A, Randomised Placebo-Controlled Trial. The Lancet Neurology (2025)

Issam A AwadRoberto J Alcazar-FelixAgnieszka StadnikSerena KinkadeAditya JhaveriJustine LeeStephanie HageJaved IqbalSean P PolsterRobert ShenkarKevin TreineNichol McBeeNoeleen OstapkovichKaren LaneJames K LiaoMatthew SorrentinoCornelia LeeKelly D FlemmingRomuald GirardTimothy J CarrollRichard E ThompsonDaniel F Hanley

neurosurgeryplacebo-controlled trialbrain tumor researchcerebral cavernous malformationsstroke rehabilitationcash epocclinical neurologycritical carevascular malformationscerebrovascular diseaseanesthesiologyvascular surgeryneurologyclinical effectivenessneurovascular diseasesvascular biologyneuropharmacologybrain injurystroke

Endothelial Oestrogen–Myocardial Cyclic Guanosine Monophosphate Axis Critically Determines Angiogenesis and Cardiac Performance During Pressure Overload. Cardiovascular Research (2024)

Nobuaki FukumaHiroyuki TokiwaGenri NumataKazutaka UedaPang-Yen LiuMiyu TajimaYu OtsuTaro KariyaYukio HiroiJames K LiaoIssei KomuroEiki Takimoto

cardiologyangiogenesisphysiologycardiovascular physiologycardiovascular functioncardiovascular researchmyocardial cgmp axiscardiac performancevascular biologyendothelial estrogen

Endothelial Rho Kinase Controls Blood Vessel Integrity and Angiogenesis. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Martin LangeCaitlin FrancisJessica FurtadoYoung-Bum KimJames K LiaoAnne Eichmann

angiogenesiscell biologymolecular biologyblood vesselsendothelial rho kinaseblood vessel integrityvascular biology

Loss of Arnt in Endothelial Cells Mediated Inflammation Pathway Promotes Diabetic Cardiac Vascular Dysfunction. Free Radical Biology and Medicine (2024)

Snekha RajasekaranMei ZhengMaura KnappKarim UllahQin ZhangYan LiQiaozhu SuJames K. LiaoQiong ZhaoRongxue Wu

diabetesendothelial dysfunctionvascular diseaseendothelial cellsarterial diseaseinflammation pathwayinflammationvascular agingvascular biologycardiovascular diseasefree radical biologymedicine

Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations. Neurology Genetics (2024)

Cenk AyataHelen KimLeslie MorrisonJames K. LiaoJuan GutierrezMiguel Lopez-ToledanoEnrique CarrazanaAdrian L. RabinowiczIssam A. Awad

cerebrovascular diseaseneuroscienceneurogeneticsneurologyrho-associated kinasestrokeneuroanatomyneuropathologyneuroradiologyrenal pathophysiologycerebral cavernous malformationsgenetics

Abstract P2127: A Novel Arnt Dependent Hif2A Singling in Protecting Against Cardiac Microvascular Endothelial Barrier Dysfunction Following Myocardial Infarction. Circulation Research (2023)

Karim Karim UllahLizhuo AiYan LiLifeng LiuKaichao PanZainab HumayunAlbert SitikovQiaozhu SuQiong ZhaoWillard W SharpYun FangDavid WuJames K LiaoRongxue R Wu

pharmacologyimmunologycardiologynephrologyendothelial dysfunctionmyocardial infarctioncirculatory physiologyhealth sciencesmicrovascular dysfunctioncardiovascular physiologyinflammationcardiovascular functioncardiovascular researchhematologyrespiratory medicinevascular biologycardiovascular diseasepreventive medicine

A Novel Arnt-Dependent Hif-2α Signaling as a Protective Mechanism for Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Karim UllahLizhuo AiYan LiLifeng LiuQin ZhangKaichao PanZainab HumayunLin PiaoAlbert SitikovQiaozhu SuQiong ZhaoWillard SharpYun FangDavid WuJames K. LiaoRongxue Wu

cardiologymyocardial infarctionmolecular biologymicrovascular dysfunctioncardiovascular researchbiophysicsprotective mechanismvascular biology

Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption. Circulation Research (2023)

Georgia ZarkadaXun ChenXuetong ZhouMartin LangeLei ZengWenyu LvXuan ZhangYunhua LiWeibin ZhouKeli LiuDongying ChenNicolas RicardJames LiaoYoung-Bum KimRui BeneditoLena Claesson-WelshKari AlitaloMichael SimonsRong JuXuri LiAnne EichmannFeng Zhang

tumor biologyintestinal lipid absorptionhepatologycell biologycirculatory physiologyhealth sciencesmembrane biologynutrient physiologyendocrinologyphysiologyliver physiologylacteal permeabilitycardiovascular researchgastroenterologyvascular biology

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James K. Liao

University of Chicago

Affiliations

Medicine, Department of

James K. Liao is currently serving as a Medicine, Department Of MD at University of Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James K. Liao

University of Chicago

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Induction of Adipocyte Thermogenic Program by Rho-Associated Coiled-Coil Containing Kinase 2. iScience (2026)

bioenergeticssignal transductionmolecular physiologycell signalingmolecular metabolismphysiologymetabolismmolecular and cellular biologycell metabolismenergy metabolismmetabolic regulation

Recurrent Symptomatic Hemorrhage in Cerebral Cavernous Malformations After Discontinuation of Atorvastatin or Placebo. Journal of the American Heart Association (2026)

vascular malformationscardiologycerebral blood flowcerebrovascular diseaseneurologybrain injuryblood vesselsstrokeneuropathologycardiovascular disease

Safety and Efficacy of Atorvastatin for Rebleeding in Cerebral Cavernous Malformations (at Cash Epoc): A Phase 1/2A, Randomised Placebo-Controlled Trial. The Lancet Neurology (2025)

Endothelial Oestrogen–Myocardial Cyclic Guanosine Monophosphate Axis Critically Determines Angiogenesis and Cardiac Performance During Pressure Overload. Cardiovascular Research (2024)

Nobuaki FukumaHiroyuki TokiwaGenri NumataKazutaka UedaPang-Yen LiuMiyu TajimaYu OtsuTaro KariyaYukio HiroiJames K LiaoIssei KomuroEiki Takimoto

cardiologyangiogenesisphysiologycardiovascular physiologycardiovascular functioncardiovascular researchmyocardial cgmp axiscardiac performancevascular biologyendothelial estrogen

Endothelial Rho Kinase Controls Blood Vessel Integrity and Angiogenesis. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Martin LangeCaitlin FrancisJessica FurtadoYoung-Bum KimJames K LiaoAnne Eichmann

angiogenesiscell biologymolecular biologyblood vesselsendothelial rho kinaseblood vessel integrityvascular biology

Loss of Arnt in Endothelial Cells Mediated Inflammation Pathway Promotes Diabetic Cardiac Vascular Dysfunction. Free Radical Biology and Medicine (2024)

Snekha RajasekaranMei ZhengMaura KnappKarim UllahQin ZhangYan LiQiaozhu SuJames K. LiaoQiong ZhaoRongxue Wu

diabetesendothelial dysfunctionvascular diseaseendothelial cellsarterial diseaseinflammation pathwayinflammationvascular agingvascular biologycardiovascular diseasefree radical biologymedicine

Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations. Neurology Genetics (2024)

Cenk AyataHelen KimLeslie MorrisonJames K. LiaoJuan GutierrezMiguel Lopez-ToledanoEnrique CarrazanaAdrian L. RabinowiczIssam A. Awad

cerebrovascular diseaseneuroscienceneurogeneticsneurologyrho-associated kinasestrokeneuroanatomyneuropathologyneuroradiologyrenal pathophysiologycerebral cavernous malformationsgenetics

Abstract P2127: A Novel Arnt Dependent Hif2A Singling in Protecting Against Cardiac Microvascular Endothelial Barrier Dysfunction Following Myocardial Infarction. Circulation Research (2023)

Karim Karim UllahLizhuo AiYan LiLifeng LiuKaichao PanZainab HumayunAlbert SitikovQiaozhu SuQiong ZhaoWillard W SharpYun FangDavid WuJames K LiaoRongxue R Wu

Karim UllahLizhuo AiYan LiLifeng LiuQin ZhangKaichao PanZainab HumayunLin PiaoAlbert SitikovQiaozhu SuQiong ZhaoWillard SharpYun FangDavid WuJames K. LiaoRongxue Wu

cardiologymyocardial infarctionmolecular biologymicrovascular dysfunctioncardiovascular researchbiophysicsprotective mechanismvascular biology

Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption. Circulation Research (2023)

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