Jessica Castle

Jessica Castle is a Senior Professor at Oregon Health & Science University specializing in endocrinology, diabetes technology, and insulin delivery. Her research focuses on optimizing type 1 and type 2 diabetes management through continuous glucose monitoring, automated insulin delivery systems, and pharmacologic therapies. Her latest work evaluates hybrid closed-loop systems that automate meal dosing, prediction-based bedtime interventions for nocturnal hypoglycemia prevention, and digital twin models for exercise decision support. She also investigates GLP-1-based therapy optimization guided by CGM data and renal outcomes in insulin-treated patients with chronic kidney disease. Her studies have been published in Diabetes Care and Diabetes.