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Jeffrey A. Medin, PhD, is a Professor of Pediatrics (Hematology/Oncology) at the Medical College of Wisconsin. His research focuses on molecular genetics, gene therapy, and immunotherapy, with a specific emphasis on lentivirus-mediated gene therapy for Fabry disease and acid ceramidase deficiency. He led the Canadian FACTs trial, reporting 5-year end-of-study results in 2025, and has investigated ceramide metabolism alterations in melanoma resistance to immune checkpoint inhibitors. His work also explores hematopoietic stem cell transplantation for metabolic correction and NK cell responses in sarcoma. He maintains extensive international collaborations across Canada, France, Japan, Germany, and Australia.
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