Faculty

Institution

Unit

Venue

Jeff Chan

Associate Professor of Chemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

Department of Chemistry

School of Chemical Sciences

School of Molecular & Cellular Biology

Department of Biochemistry

School of Chemical Sciences

Department of Chemistry

Jeff Chan is currently serving as a College Of Liberal Arts & Sciences Associate Professor of Chemistry at Uiuc.

Honors

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Experiences

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Education

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Jeff Chan

UIUC

Associate Professor of Chemistry

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photomedicine biophysics biochemistry biophotonics molecular imaging biomedical imaging biological imaging biomedical engineering fluorescence biomedical analysis cancer imaging biomolecular engineering chemical probes novel imaging methods biomedical photonics fluorescence spectroscopy biological chemistry photophysical properties enzymes chemical biology molecular cancer luminescence tissue imaging medical optical imaging biochemical sciences vibrational spectroscopy biomolecules tumor targeting light science redox biology translational molecular imaging photodynamic therapy nitric oxide chemical sciences single-molecule detection bio-orthogonal chemistry cancer biology cellular biochemistry cell metabolism molecular physiology metalloproteins enzyme catalysis biocatalysis chemical image near-infrared spectroscopy photoacoustic imaging oncologic imaging optical imaging contrast agents therapeutic imaging imaging agent enzyme specificity structure-function enzyme kinetics enzymatic modification disease biomarkers lipid synthesis tissue oxygenation biological inorganic chemistry therapeutic nanomaterials nitrosative stress reactive nitrogen species glycosylation reactive oxygen species photoacoustic probes escherichia coli elevated glutathione acoustogenic probes pa probes pa probe development transition-state structure transition state chemoselective bioimaging maintain copper homeostasis fa stress reaction-based fluorescent probe formaldehyde probe 1 controlled release complex molecule synthesis drug delivery

Notable Scholarly Works

Notable Federal Grants

Collaborators

Activatable Porphyrin-Based Sensors, Photosensitizers and Combination Therapeutics. JACS Au (2025)

Suritra BandyopadhyayJoseph A ForzanoMusa DirakJefferson Chan

pharmacologyphotodynamic therapymolecular imagingbiomoleculesbiophysicsphotomedicinebiosensorsphototoxicityabs-modified porphyrinsbiomolecular engineeringchemical probesbiological macromoleculesbio-orthogonal chemistryphotochemistryvarious disease biomarkersbiomedical analysisactivatable porphyrin-based sensors

Activity-Based Sensing Reveals Elevated Labile Copper Promotes Liver Aging via Hepatic Aldh1A1 Depletion. Nature Communications (2025)

Zhenxiang ZhaoMelissa Y. LuceroShengzhang SuEric J. ChaneyJiajie Jessica XuMichael MyszkaJefferson Chan

ageingreactive oxygen speciesliver physiologylabile copperbiomarkersredox signalingcu homeostasisbiochemistryoxidative stressfree radical biologyredox biologyantioxidantsaging cellmetabolismphysiology

Author Response for"Logic-Gated Approach for Targeted Delivery and Site-Selective Activation of Photothermal Agents in Precision Cancer Treatment". (2025)

Chang JiangZhengxiang ZhaoAmanda K. EastSuritra BandyopadhyayZiyi JiangJefferson Chan

photodynamic therapytumor targetingcancer imagingcontrolled releaseradiation oncologydrug deliveryprecision cancer treatmentbiomolecular engineeringsite-specific deliveryauthor responsephotomedicinetargeted deliverybiomedical engineeringtherapeutic targets

Editorial Overview: Editorial of Molecular Imaging. Current Opinion in Chemical Biology (2025)

Jefferson ChanMartin J Schnermann

molecular imagingcancer imagingtranslational molecular imagingmolecular biologymedical imagingbiomedical imagingtranslational imagingradiologybiomedical analysisnuclear medicine

Logic-Gated Approach for Targeted Delivery and Site-Selective Activation of Photothermal Agents in Precision Cancer Treatment. Chemical Science (2025)

Chang JiangZhengxiang ZhaoAmanda K. EastSuritra BandyopadhyayZiyi JiangJefferson Chan

photodynamic therapytumor targetingradiation oncologybiomolecular engineeringlogic-gated approachtumor biologyphotomedicinecancer cellsselective cancer therapiesbiophotonicstherapeutic targets

Activity-Based Bioluminescent Logic-Gate Probe Reveals Crosstalk Between the Inflammatory Tumor Microenvironment and Aldh1A1 in Cancer Cells. JACS Au (2024)

Chelsea B. SwartchickMusa DirakLily C. F. WengerRodrigo Tapia HernandezMichael C. LeeJefferson Chan

cancer biologymolecular cancerbreast cancercancer cellstumor microenvironmentcancer researchradiation oncologytumor biologycell biologyretinoic acidcancer growth

Activity-Based Nitric Oxide-Responsive Porphyrin for Site-Selective and Nascent Cancer Ablation. ACS Applied Materials & Interfaces (2024)

Suritra BandyopadhyayZhenxiang ZhaoAmanda K. EastRodrigo Tapia HernandezJoseph A. ForzanoBenjamin A. ShapiroAnuj K. YadavChelsea B. SwartchickJefferson Chan

nanoparticle researchtumor growthphotodynamic therapymolecular imagingcancer imagingtumor targetingmurine breast cancerphotomedicinetransition metal chemistrytherapeutic nanomaterialsradiation oncologybiomolecular engineeringphotochemistrystandard porphyrinfluorescencefluorescence spectroscopychemistry

Exploring Biliverdin’s Molecular Interactions With Cu- and Fe-Based Mofs: A Unified in Vitro Study With Photoacoustic Analysis. Langmuir (2024)

Hamideh R. AlanaghParinaz FathiHailey J. KnoxParikshit MoitraJefferson ChanDipanjan Pan

supramolecular photochemistrymolecular interactionstransition metal chemistrybiochemistrymolecular sciencecoordination chemistryphotophysical propertiesfe-based mofsphotomedicinebvd loadingfluorescencefluorescence spectroscopychemistry

Neutrophils Exposed to a Cholesterol Metabolite Secrete Extracellular Vesicles That Promote Epithelial-Mesenchymal Transition and Stemness in Breast Cancer Cells. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Natalia KrawczynskaYu WangKi LimAnasuya Das GuptaAdam LenczowskiMarwan AbughazalehShruti V. BendreLara I. KockayaClaire P. SchaneYifan FeiAlvaro G HernandezJenny DrnevichJefferson ChanLawrence W. DobruckiMarni D. BoppartJulie OstranderErik R. Nelson

cancer biologymolecular cancerbreast cancercancer cellstumor microenvironmentbiological microenvironmentscholesterol metabolitetumor biologyimmunologycancer pathophysiology27hc-modulated neutrophilscell biologycancer growth

Optical Imaging Probes for Selective Detection of Butyrylcholinesterase. Journal of Materials Chemistry B (2024)

Musa DirakJefferson ChanSafacan Kolemen

biomedical analysisbiological imagingbiophysicsbiochemical sciencesbiomedical photonicsbiochemistryoptical imaging probesoptical probeschemical probesbche activitybiomedical opticsoptical imagingbiophotonicsmedical optical imagingvibrational spectroscopy

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Jeff Chan

Associate Professor of Chemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

Department of Chemistry

School of Chemical Sciences

School of Molecular & Cellular Biology

Department of Biochemistry

School of Chemical Sciences

Department of Chemistry

Jeff Chan is currently serving as a College Of Liberal Arts & Sciences Associate Professor of Chemistry at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jeff Chan

UIUC

Associate Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Activatable Porphyrin-Based Sensors, Photosensitizers and Combination Therapeutics. JACS Au (2025)

Suritra BandyopadhyayJoseph A ForzanoMusa DirakJefferson Chan

Activity-Based Sensing Reveals Elevated Labile Copper Promotes Liver Aging via Hepatic Aldh1A1 Depletion. Nature Communications (2025)

Zhenxiang ZhaoMelissa Y. LuceroShengzhang SuEric J. ChaneyJiajie Jessica XuMichael MyszkaJefferson Chan

Author Response for"Logic-Gated Approach for Targeted Delivery and Site-Selective Activation of Photothermal Agents in Precision Cancer Treatment". (2025)

Chang JiangZhengxiang ZhaoAmanda K. EastSuritra BandyopadhyayZiyi JiangJefferson Chan

Editorial Overview: Editorial of Molecular Imaging. Current Opinion in Chemical Biology (2025)

Jefferson ChanMartin J Schnermann

molecular imagingcancer imagingtranslational molecular imagingmolecular biologymedical imagingbiomedical imagingtranslational imagingradiologybiomedical analysisnuclear medicine

Logic-Gated Approach for Targeted Delivery and Site-Selective Activation of Photothermal Agents in Precision Cancer Treatment. Chemical Science (2025)

Chang JiangZhengxiang ZhaoAmanda K. EastSuritra BandyopadhyayZiyi JiangJefferson Chan

photodynamic therapytumor targetingradiation oncologybiomolecular engineeringlogic-gated approachtumor biologyphotomedicinecancer cellsselective cancer therapiesbiophotonicstherapeutic targets

Activity-Based Bioluminescent Logic-Gate Probe Reveals Crosstalk Between the Inflammatory Tumor Microenvironment and Aldh1A1 in Cancer Cells. JACS Au (2024)

Chelsea B. SwartchickMusa DirakLily C. F. WengerRodrigo Tapia HernandezMichael C. LeeJefferson Chan

cancer biologymolecular cancerbreast cancercancer cellstumor microenvironmentcancer researchradiation oncologytumor biologycell biologyretinoic acidcancer growth

Activity-Based Nitric Oxide-Responsive Porphyrin for Site-Selective and Nascent Cancer Ablation. ACS Applied Materials & Interfaces (2024)

Suritra BandyopadhyayZhenxiang ZhaoAmanda K. EastRodrigo Tapia HernandezJoseph A. ForzanoBenjamin A. ShapiroAnuj K. YadavChelsea B. SwartchickJefferson Chan

Exploring Biliverdin’s Molecular Interactions With Cu- and Fe-Based Mofs: A Unified in Vitro Study With Photoacoustic Analysis. Langmuir (2024)

Hamideh R. AlanaghParinaz FathiHailey J. KnoxParikshit MoitraJefferson ChanDipanjan Pan

Optical Imaging Probes for Selective Detection of Butyrylcholinesterase. Journal of Materials Chemistry B (2024)

Musa DirakJefferson ChanSafacan Kolemen

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5
10
10 / page