Jean-Nicolas Vauthey

Jean-Nicolas Vauthey is a Professor of Surgery and a high-senior faculty member at The University of Texas MD Anderson Cancer Center, where he specializes in surgical oncology, hepatology, and gastrointestinal surgery. His research focuses on liver cancer, metastasis, and the tumor microenvironment, with recent work exploring organ preservation in rectal cancer with synchronous liver metastases, spatial transcriptomics and multiplex proteomics in colorectal carcinoma, and the optimization of thermal ablation margins for liver tumors. He has contributed to NCCN clinical practice guidelines for biliary tract cancers and has published extensively on gallbladder cancer immunogenomics and perihilar cholangiocarcinoma outcomes. His international, multi-center collaborations have advanced prognostic modeling and surgical decision-making in hepatobiliary malignancies.