Faculty

Institution

Unit

Venue

Jayalakshmi Sridhar

Xavier University of Louisiana

Affiliations

Department Of Chemistry

Department Of Institutional Advancement

Department Of Mass Communication

Department Of Pharmacy Practice

Xavier University of Louisiana

NoneJayalakshmi Sridhar is currently serving as a Chemistry faculty at Xavier University of Louisiana.

Honors

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Experiences

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Education

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Jayalakshmi Sridhar

Xavier University of Louisiana

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pharmacology drug discovery enzyme inhibition biochemistry medicinal chemistry therapeutic targets medicinal research pharmacological research pharmaceutical chemistry biomolecular engineering chemical biology drug metabolism drug development anti-cancer agents molecular biology enzymes molecular pharmacology cancer discovery rational drug design molecular cancer mechanisms of action toxicology peptide science structural molecular biology oncogenes inhibitory activity pharmaceutical sciences molecular science protein science chemical sciences pharmacotherapy breast oncology structure-function enzyme kinetics drug targets selective inhibitors biomolecular structure molecular structure cancer cells peptides molecular chemistry molecular docking selective toxicity receptor tyrosine kinases drug targeting receptor (biochemistry) system pharmacology functional selectivity protein assembly protein modeling protein chemistry psychotropic medication molecular recognition anticoagulants platelet antagonist toxicological mechanism molecular evidence single-molecule detection chemical probes intrinsic impurity clinical toxicology remedial action liver x receptors structure-activity relationships aggressive breast cancer molecular modeling studies ligand specificity factors daidzein analogues anti-estrogenic activities qsar studies thiazole derivatives biological evaluation novel inhibitors small-molecule probes active site cavities qsar models silico studies

Notable Scholarly Works

Notable Federal Grants

Collaborators

Modulation of Estrogen Receptor Activity by the Phytoalexin Tuberosin Produced From Elicited Kudzu ( Pueraria Lobata ). Journal of Natural Products (2025)

pharmacognosyreproductive biologyestrogen receptor activitynatural productselicited kudzuphysiologyovarian hormonescomparative endocrinologybioactive compoundspharmacologychemical ecologyendocrinologyreceptorsphytoalexin tuberosin producedreproductive hormoneshormonal receptor

Crystal Structure of 4-Bromo-5,7-Dimethoxy-2,3-Dihydro-1 H -Inden-1-One. Acta Crystallographica Section E Crystallographic Communications (2024)

Sri Hari GallaJayalakshmi SridharJoel T. MagueXiaodong ZhangKira D. WhiteQiang ZhangJames P. Donahue

crystal structuresx-ray crystallographycrystallography

Development of 6-Amido-4-Aminoisoindolyn-1,3-Diones as P70S6K1 Inhibitors and Potential Breast Cancer Therapeutics. Frontiers in Molecular Biosciences (2024)

drug developmentp70s6k1 inhibitorsanti-cancer agentsdrug targetsmedicinal researchbiochemistrysmall moleculesmedicinal chemistryrational drug designcancer discoverypharmacologytherapeutic targetsdrug discoverypharmacological researchenzyme inhibitionbreast cancer

Reaction Optimization Experiment for Undergraduate Capstone Organic Chemistry Laboratory Course. Journal of Chemical Education (2024)

Jayalakshmi SridharGalina Goloverda

reaction optimization experimentchemistryorganic chemistrychemistry education

Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors. Chemical Research in Toxicology (2023)

drug developmentpharmaceutical chemistrymolecular pharmacologyactive ingredientbiochemistrymedicinal chemistrybioorganic chemistrybioactive compoundsflavone-based esterspharmacologydrug metabolismdrug discoverypharmacological researchenzyme inhibitionbiological studiespotential p450 2a6

Development of Pedagogical Methods for Training Undergraduates in Skills of Science Communication to the Public. ACS symposium series (2023)

science communicationeducational strategieseducationteacher educationlearning sciencestraining undergraduatespreservice teacher educationpedagogical methodspublic relationscommunicationprofessional developmentteaching methodsscience education

Study of Ceramide-Flavone Analogs Showing Selffluorescence and Anti-Proliferation Activities. Journal of Oncology Research and Therapy (2023)

Navneet GoyalCamilla DoMiriam Hill-OdomTeresa BeamonTulasi PonnapakkamJiawang LiuJayalakshmi SridharThomas HuckabaMaryam Foroozesh

cancer researchpharmacologyceramide-flavone analogscancer treatmentoncologyanti-proliferation activities

Undergraduate Core Course on Science Communication to the Public and Its Impact on Public Policy Creation. ACS symposium series (2023)

undergraduate core coursescience communicationeducationscientific communicationundergraduate researchresearch policypublic policy creationpublic relationscommunicationscientific literacyscience policy

Abstract 343: New Derivatives of 1,3-Dioxoisoindoline: Potential Breast Cancer Therapeutics That Are S6K1 Inhibitors. Cancer Research (2022)

Satyendra KumarRajesh KomatiShahensha ShaikMelyssa BrattonLinh TranRion SamElijah Johnson-HendersonBreyanah GrahamChristopher WIlliamsJayalakshmi Sridhar

cancer biologyanti-cancer agentsmedicinal chemistrychemical derivativecancer researchpharmacologymedicinedrug discoverycancer treatmentderivative (chemistry)oncologybreast cancer

Targeting Rps6K1 for Refractory Breast Cancer Therapy. Breast Cancer (2022)

breast oncologyoncogenestumor targetingcell biologymolecular cancertumor suppressorstherapeutic targetscancer cellsbreast cancer

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Jayalakshmi Sridhar

Xavier University of Louisiana

Affiliations

Department Of Chemistry

Department Of Institutional Advancement

Department Of Mass Communication

Department Of Pharmacy Practice

Xavier University of Louisiana

NoneJayalakshmi Sridhar is currently serving as a Chemistry faculty at Xavier University of Louisiana.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jayalakshmi Sridhar

Xavier University of Louisiana

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Modulation of Estrogen Receptor Activity by the Phytoalexin Tuberosin Produced From Elicited Kudzu ( Pueraria Lobata ). Journal of Natural Products (2025)

Crystal Structure of 4-Bromo-5,7-Dimethoxy-2,3-Dihydro-1 H -Inden-1-One. Acta Crystallographica Section E Crystallographic Communications (2024)

Sri Hari GallaJayalakshmi SridharJoel T. MagueXiaodong ZhangKira D. WhiteQiang ZhangJames P. Donahue

crystal structuresx-ray crystallographycrystallography

Development of 6-Amido-4-Aminoisoindolyn-1,3-Diones as P70S6K1 Inhibitors and Potential Breast Cancer Therapeutics. Frontiers in Molecular Biosciences (2024)

Reaction Optimization Experiment for Undergraduate Capstone Organic Chemistry Laboratory Course. Journal of Chemical Education (2024)

Jayalakshmi SridharGalina Goloverda

reaction optimization experimentchemistryorganic chemistrychemistry education

Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors. Chemical Research in Toxicology (2023)

Development of Pedagogical Methods for Training Undergraduates in Skills of Science Communication to the Public. ACS symposium series (2023)

Study of Ceramide-Flavone Analogs Showing Selffluorescence and Anti-Proliferation Activities. Journal of Oncology Research and Therapy (2023)

Navneet GoyalCamilla DoMiriam Hill-OdomTeresa BeamonTulasi PonnapakkamJiawang LiuJayalakshmi SridharThomas HuckabaMaryam Foroozesh

cancer researchpharmacologyceramide-flavone analogscancer treatmentoncologyanti-proliferation activities

Undergraduate Core Course on Science Communication to the Public and Its Impact on Public Policy Creation. ACS symposium series (2023)

Abstract 343: New Derivatives of 1,3-Dioxoisoindoline: Potential Breast Cancer Therapeutics That Are S6K1 Inhibitors. Cancer Research (2022)

Satyendra KumarRajesh KomatiShahensha ShaikMelyssa BrattonLinh TranRion SamElijah Johnson-HendersonBreyanah GrahamChristopher WIlliamsJayalakshmi Sridhar

cancer biologyanti-cancer agentsmedicinal chemistrychemical derivativecancer researchpharmacologymedicinedrug discoverycancer treatmentderivative (chemistry)oncologybreast cancer

Targeting Rps6K1 for Refractory Breast Cancer Therapy. Breast Cancer (2022)

breast oncologyoncogenestumor targetingcell biologymolecular cancertumor suppressorstherapeutic targetscancer cellsbreast cancer

1
2
3
4
5
10 / page