Jay L. Mellies

Amgen-Perlmutter Professor of Biology

Reed College

Affiliations

Laboratories Of Kleinholtz Biological

Department Of Biology

History and Social Sciences

History

Reed College

Jay L. Mellies is currently serving as a Biology Amgen-Perlmutter Professor of Biology at Reed College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jay L. Mellies

Reed College

Amgen-Perlmutter Professor of Biology

You can click a keyword to filter the displayed items

microbiology pathogenic bacteria microbial pathogenesis bacteria applied microbiology infectious diseases pathogenesis clinical microbiology virulence factors pathogens molecular microbiology microorganisms environmental microbiology bacteriology plastic degradation molecular biology microbiological degradation pathology biofilms digestive diseases polymer degradation gut microbes degradable plastic bioremediation structural molecular biology microbial cell factory environmental technology protein secretion enteropathogenic escherichia coli infection control antimicrobial agents hazardous materials pathogen characterization plastic recycling microbial physiology biomolecular structure nucleic acids animal science livestock science microbial disease viral pathogenesis pathogen transmission plastic pollution bioplastics microbial genetics pathogen detection enterocyte effacement caenorhabditis elegans ovis canadensis bighorn sheep gene regulation transcription regulation pathway analysis veterinary microbiology secretory pathway microbial toxins chromatin remodeling nucleic acid chemistry traveler diarrhea molecular epidemiology host-microbe interactions disease progression host factors medical microbiology signaling pathways regulatory cascade non-lee-encoded virulence factors type iii secretion espc gene infant diarrhea espc enterotoxin activity mixed plastic waste multiple plastic types microbial consortia sos regulation five environmental bacterial

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ancestral Hydrocarbon Metabolism Enables Pet Degradation by a Natural Bacterial Consortium. bioRxiv (Cold Spring Harbor Laboratory) (2026)

microbial consortiumapplied microbiologyextremophilesmolecular metabolismmicrobiological degradationnatural bacterial consortiummicroorganismsmicrobial physiologybiochemistrymicrobiologybacteriabioenergeticsmicrobial geneticsmetabolic pathway analysisenvironmental microbiologymicrobial ecology

Abstract 1446 Towards Recyplable Pe Plastic: Identification of a Pe-Degrading Enzyme From a Environmentally Isolated Bacterial Consortium. Journal of Biological Chemistry (2025)

biological engineeringapplied microbiologyabstract 1446microbiological degradationmicroorganismsbiofilmsplastic degradationdegradable plasticmicrobiologybiotechnologybacteriaenvironmental biotechnologyisolated bacterial consortiumpe-degrading enzymeenvironmental microbiology

A Cytochrome P450 Facilitates Polyethylene Metabolism in a Microbial Community. International Journal of Molecular Sciences (2025)

microbial consortiumapplied microbiologymicrobiological degradationmicrobial communitymicroorganismsmicrobial physiologybiochemistrymicrobiologybacteriaenvironmental biotechnologycarbonyl metabolismenvironmental microbiologymicrobial ecology

Evaluation of Low-Density Polyethylene Degradation Using a New Thermophilic Bacterial Isolate. The Science of The Total Environment (2025)

biological engineeringpolymer sciencechemical engineeringbiofilmsplastic degradationdegradable plasticmicrobiologypolymer degradationlow-density polyethylene degradationpolymer stabilityapplied microbiology

Review of:"Polyethylene Terephthalate (Pet) Primary Degradation Products Affect C-DI-Gmp-, Camp-Signaling, and Quorum Sensing (Qs) in Vibrio Gazogenes Dsm 21264". (2025)

environmental technologyhazardous materialspolyethylene terephthalateenvironmental toxicologyecotoxicologypolycyclic aromatic hydrocarbonsplastic degradationbiochemistrypolymer degradationbiotechnologyquorum sensingbiomolecular engineering

Increased Thermal Stability and Retained Antibacterial Properties in a Sulbactam and Amantadine Salt: Towards Effective Antibacterial–Antiviral Combination Therapies. RSC Pharmaceutics (2024)

biological engineeringantibacterial propertiesantimicrobial agentsthermal stabilityantiviral compoundsantiviral drugsantimicrobial resistancemicrobiologyantiviral researchantimicrobial compoundsantibacterial agentsamantadine saltantibioticsbiomolecular engineering

Polymorphism Control of Polyethylene Terephthalate (Pet) Degradation Product via Mechanochemistry Leads to Accelerated Microbial Degradation. RSC Mechanochemistry (2024)

hazardous materialsprocess biochemistrypolymorphism controldegradable plasticmicrobial cell factorybioproductspolymer chemistrymicrobial degradationpolyethylene terephthalateplastic degradationenvironmental remediationsustainable polymersbioplasticsenvironmental technologybiochemical engineeringchemical engineeringmicrobiological degradationpolymer testingpolymer degradationbiotechnologybiomanufacturingbiomolecular engineering

Two-Step Chemo-Microbial Degradation of Post-Consumer Polyethylene Terephthalate (Pet) Plastic Enabled by a Biomass-Waste Catalyst. Bioengineering (2023)

environmental technologywaste managementchemical engineeringplastic degradationenvironmental remediationpolymer degradationbioremediationenvironmental engineeringplastic recyclingtwo-step chemo-microbial degradationbioresource technologypost-consumer polyethylene terephthalatebiomass-waste catalyst

Microbial Consortia and Mixed Plastic Waste: Pangenomic Analysis Reveals Potential for Degradation of Multiple Plastic Types via Previously Identified Pet Degrading Bacteria. International Journal of Molecular Sciences (2022)

microbial consortiumapplied microbiologymixed plastic wastemultiple plastic typesmicrobiological degradationbiofilmsplastic degradationmicrobiologybioremediationmicrobial consortiaenvironmental engineeringplastic recyclingplastic pollutionenvironmental microbiologymicrobial ecologyrecycling

Environmental Consortium Containing Pseudomonas and Bacillus Species Synergistically Degrades Polyethylene Terephthalate Plastic. mSphere (2020)

hazardous materialsdegradable plasticbacteriamicrobial cell factoryplastic pollutionbioproductspolymer chemistryplastic degradationenvironmental remediationbioplasticsenvironmental technologymicroorganismsmicrobiologywastewater treatmentplastic recyclingenvironmental microbiologyapplied microbiologybiofilmspolymer degradationbioremediationenvironmental engineering