Faculty

Institution

Unit

Venue

Jay Hirsh

Professor of Biology; Director of Undergraduate Program in Neuroscience

University of Virginia

Affiliations

College and Graduate School of Arts and Sciences

Department of Biology

Jay Hirsh is currently serving as a College And Graduate School Of Arts And Sciences Professor of Biology; Director of Undergraduate Program in Neuroscience at University of Virginia.

Honors

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Experiences

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Education

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Jay Hirsh

University of Virginia

Professor of Biology; Director of Undergraduate Program in Neuroscience

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insect molecular biology developmental biology genetics gene expression molecular genetics neuroscience molecular cell biology biology developmental genetics neurons molecular neuroscience neuropsychopharmacology dopamine developmental system neurotransmitters behavioral neuroscience gene regulation gene function nervous system molecular and cellular biology neuropharmacology developmental cell neurotransmission molecular neurobiology gene structure insect biochemistry nucleic acids chronobiology addiction biology genome biology molecular neurodegeneration neurobiological mechanisms neurochemistry drosophila melanogaster molecular physiology genetic mechanisms cellular neurobiology insect science rna processing splicing variant neural mechanisms genomic mechanisms cellular physiology pharmacological research evolutionary developmental biology biological psychology cryptochromes light regulation fruit fly ddc genes biomedical imaging psychoneuroendocrinology molecular regulation behavioural pharmacology behavioural physiology comparative physiology gene regulatory networks invertebrate vision transcription regulation integrative biology experimental biology tdc genes dopamine neurons memory dynamics ddc expression dopa decarboxylase ddc gene biogenic amines serotonin neurons drosophila tyrosine hydroxylase dopaminergic neurons reward systems therapeutic imaging abstract dopamine drosophila th gene dopaminergic cells

Notable Scholarly Works

Notable Federal Grants

Collaborators

Non-Uniform Chromosomal Snp Density Biases Sites of Meiotic Crossovers in Drosophila Melanogaster. G3 Genes Genomes Genetics (2026)

reproductive biologyinsect molecular biologygenomic mechanismsevolutionary applicationsmolecular geneticsgene evolutiondevelopmental systempopulation geneticsgeneticslinkage disequilibriumchromosome biologymolecular evolutiongenetic variationgenetic recombinationchromosomal rearrangementsgenome biologyevolutionary biologyhereditymeiotic crossovers

Reduced Expression of the Electron Transport Chain Component AtpsynβL in Glutamate Neurons Changes Drosophila Melanogaster Sleep Patterns Through Adulthood.. PubMed (2026)

molecular and cellular biologyinsect molecular biologymolecular neurodegenerationphysiologyneuronsneuropsychopharmacologyneurosciencemolecular physiologyneurophysiologymolecular neuroscienceneurotransmissionneurotransmitters

CORRECTION: Nitric Oxide Acts as a Cotransmitter in a Subset of Dopaminergic Neurons to Diversify Memory Dynamics. eLife (2020)

Yoshinori AsouRobert P RayXi LongDaniel BusheyKarol CichewiczTeri-TB NgoBrandi SharpChristina ChristoforouAmy HuAndrew L LemirePaul TillbergJay HirshAshok Litwin-KumarGerald M Rubin

neurologyneural scienceneurochemistryneuropharmacologyelectrophysiologycognitive neuroscienceneurosciencememory dynamicsdopaminergic neurons

An Inexpensive Air Stream Temperature Controller and Its Use to Facilitate Temperature-Controlled Behavior in Drosophila. BioTechniques (2019)

Ryan SangstonJay Hirsh

insect molecular biologyexperimental biologyneural circuitsinsect biochemistrytemperature-inducible channel dtrpa1optogeneticsphysiologycomparative physiologytemperature-modulated biological reagentsneuronsbiologynervous systemneurotransmissiondopaminergic neuronsneural mechanisms

Differential Susceptibility to Reduced Dopamine in Snc Versus Vta in a Mouse Tyrosine Hydroxylase Ko Model of Parkinson's Disease. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Michal KoltunKarol CichewiczJeffrey Thomas GibbsMartin DarvasJay Hirsh

neurologymolecular neurodegenerationdopamine lossdecreased brain dopamineneuropsychopharmacologyparkinson's diseaseneurodegenerative diseasesneurosciencedopaminemolecular neurobiologymolecular neurosciencedifferential susceptibility

Nitric Oxide Acts as a Cotransmitter in a Subset of Dopaminergic Neurons to Diversify Memory Dynamics. eLife (2019)

Yoshinori AsoRobert P RayXi LongDaniel BusheyKarol CichewiczTeri-TB NgoBrandi SharpChristina ChristoforouAmy HuAndrew L LemirePaul TillbergJay HirshAshok Litwin-KumarGerald M Rubin

insect molecular biologyneural circuitsneuronsneuropsychopharmacologyneuroscienceneurobiological mechanismsbiologynitric oxide actsmemory dynamicsmolecular neuroscienceneurotransmissionneurotransmittersneural mechanismsnitric oxide

A Diversity of Transcriptional Responses to Reduced Dopamine in Snc and Vta in a Mouse Tyrosine Hydroxylase Ko Model of Parkinson\'S Disease. bioRxiv (Cold Spring Harbor Laboratory) (2018)

Michal KoltunKarol CichewiczJeffrey Thomas GibbsMartin DarvasJay Hirsh

dopamine transportermolecular neurodegenerationdopamine lossdopamineneuroscienceparkinson's diseaseneurodegenerative diseasescell metabolismmolecular neurobiologybrain dopaminemolecular neurosciencesystems biologygenetics

Rnai Targeting of the Respiratory Chain Affects Drosophila Life Span Depending on Neuronal Subtype. BIOS (2018)

Laura J.W. KeppleyAndrew J. NafzigerYi-Ting LiuJay HirshJeffrey M. Copeland

molecular and cellular biologyaging cellinsect molecular biologyphysiologyneuronsbiogerontologyneuronal subtypedrosophila life spandevelopmental biologymolecular cell biologyrnai targetinglifespan extensionlongevity

Shinyr-Dam: A Program Analyzing Drosophila Activity, Sleep and Circadian Rhythms. Communications Biology (2018)

Karol CichewiczJay Hirsh

insect molecular biologydrosophila locomotor activitybiological datadrosophila activity monitordata and information visualizationchronobiologydrosophila activitystatistical softwarebiologydata sciencequantitative biology

Shinyr-Dam_supplementary_files. Figshare (2018)

Karol CichewiczJay Hirsh

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Jay Hirsh

Professor of Biology; Director of Undergraduate Program in Neuroscience

University of Virginia

Affiliations

College and Graduate School of Arts and Sciences

Department of Biology

Jay Hirsh is currently serving as a College And Graduate School Of Arts And Sciences Professor of Biology; Director of Undergraduate Program in Neuroscience at University of Virginia.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jay Hirsh

University of Virginia

Professor of Biology; Director of Undergraduate Program in Neuroscience

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Non-Uniform Chromosomal Snp Density Biases Sites of Meiotic Crossovers in Drosophila Melanogaster. G3 Genes Genomes Genetics (2026)

Reduced Expression of the Electron Transport Chain Component AtpsynβL in Glutamate Neurons Changes Drosophila Melanogaster Sleep Patterns Through Adulthood.. PubMed (2026)

CORRECTION: Nitric Oxide Acts as a Cotransmitter in a Subset of Dopaminergic Neurons to Diversify Memory Dynamics. eLife (2020)

Yoshinori AsouRobert P RayXi LongDaniel BusheyKarol CichewiczTeri-TB NgoBrandi SharpChristina ChristoforouAmy HuAndrew L LemirePaul TillbergJay HirshAshok Litwin-KumarGerald M Rubin

neurologyneural scienceneurochemistryneuropharmacologyelectrophysiologycognitive neuroscienceneurosciencememory dynamicsdopaminergic neurons

An Inexpensive Air Stream Temperature Controller and Its Use to Facilitate Temperature-Controlled Behavior in Drosophila. BioTechniques (2019)

Ryan SangstonJay Hirsh

Differential Susceptibility to Reduced Dopamine in Snc Versus Vta in a Mouse Tyrosine Hydroxylase Ko Model of Parkinson's Disease. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Michal KoltunKarol CichewiczJeffrey Thomas GibbsMartin DarvasJay Hirsh

Nitric Oxide Acts as a Cotransmitter in a Subset of Dopaminergic Neurons to Diversify Memory Dynamics. eLife (2019)

Yoshinori AsoRobert P RayXi LongDaniel BusheyKarol CichewiczTeri-TB NgoBrandi SharpChristina ChristoforouAmy HuAndrew L LemirePaul TillbergJay HirshAshok Litwin-KumarGerald M Rubin

A Diversity of Transcriptional Responses to Reduced Dopamine in Snc and Vta in a Mouse Tyrosine Hydroxylase Ko Model of Parkinson\'S Disease. bioRxiv (Cold Spring Harbor Laboratory) (2018)

Michal KoltunKarol CichewiczJeffrey Thomas GibbsMartin DarvasJay Hirsh

Rnai Targeting of the Respiratory Chain Affects Drosophila Life Span Depending on Neuronal Subtype. BIOS (2018)

Laura J.W. KeppleyAndrew J. NafzigerYi-Ting LiuJay HirshJeffrey M. Copeland

Shinyr-Dam: A Program Analyzing Drosophila Activity, Sleep and Circadian Rhythms. Communications Biology (2018)

Karol CichewiczJay Hirsh

Shinyr-Dam_supplementary_files. Figshare (2018)

Karol CichewiczJay Hirsh

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