Faculty

Institution

Unit

Venue

Jason DeBruyne

Associate Professor

Morehouse School of Medicine

Affiliations

Department of Pharmacology & Toxicology

MSM External Event Request Form

Pharmacology & Toxicology

Jason Debruyne is currently serving as a Pharmacology & Toxicology Associate Professor at Morehouse School of Medicine.

Honors

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Experiences

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Education

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Jason DeBruyne

Morehouse School of Medicine

Associate Professor

You can click a keyword to filter the displayed items

chronobiology neuroscience molecular biology physiology cryptochromes genetics gene expression sleep signal transduction molecular and cellular biology mammalian biology molecular cell biology homeostatic mechanisms molecular regulation pineal research liver physiology melatonin vision research transcription factors epigenetics endocrinology pathogenesis infection control genome biology molecular metabolism cell metabolism protein science healthcare-associated infections skeletal muscle metabolic regulation chlamydia infection shift work animal physiology psychoneuroendocrinology aging cell venereology performance art american humor medicinal research dopamine retina time perception sleep medicine sleep disorders cellular senescence hauntology apathy mourning receptor (biochemistry) endocrine research neurochemistry occupational epidemiology neurophysiological biomarkers neurological function epidemiological outcome mitochondrial function photoreceptor cells protein function signaling pathways experimental ophthalmology experimental neuropathology molecular neurobiology transcription factor encyclopedia receptor activation clock protein mouse circadian system mammalian circadian clock reverbα degradation ubiquitin ligase siah2 photic resetting clock-deficient mice chlamydia infectivity angelman syndrome sleep regulation circadian proteomes circadian rhythms sex disparity obesity

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bmal1 Deletion Alters Mitochondrial Microstructure and Function in Mouse Cone Photoreceptors. iScience (2025)

molecular cell biologymitochondrial functioncell metabolismmolecular physiologymolecular biologycellular physiologymouse cone photoreceptorsmolecular neurosciencecell signalingphotoreceptor cellscell biologymolecular and cellular biologycellular biochemistry

Retrospective Discrimination of Pnes and Epileptic Seizure Types Using Blood Rna Signatures. Journal of Neurology (2025)

neurological functionneurologymolecular psychiatryretrospective discriminationneuroscienceneurophysiological biomarkerstranscriptomeneurophysiologymolecular diagnosticsepileptic seizure typesblood rna signaturesepilepsy

Environmental Circadian Disruption Re-Writes Liver Circadian Proteomes. Nature Communications (2024)

Hao A DuongKenkichi BabaJason P DeBruyneAlec J DavidsonChristopher EhlenMichael PowellGianluca Tosini

hepatologyenvironmental scienceecologyliver physiologycircadian proteomessystems biologycryptochromeschronobiology

Environmental Circadian Disruption Re-Programs Liver Circadian Gene Expression. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Hao A. DuongKenkichi BabaJason P. DeBruyneAlec J. DavidsonChristopher EhlenMichael PowellGianluca Tosini

hepatologygene expressionenvironmental scienceliver physiologymolecular biologysystems biologycryptochromescircadian gene expressionchronobiology

Lysine-Independent Ubiquitination and Degradation of Rev-Erbα Involves a Bi-Functional Degradation Control Sequence at Its N-Terminus. bioRxiv (Cold Spring Harbor Laboratory) (2023)

molecular cell biologyprotein engineeringsignal transductionbiological chemistrymolecular metabolismbiochemistrymolecular biologyprotein functionlysine-independent ubiquitinationcell signalingcell biologymolecular and cellular biologyprotein sciencecellular biochemistrymolecular regulation

The Circadian Clock Mediates the Response to Oxidative Stress in a Cone Photoreceptor‒Like (661W) Cell Line via Regulation of Glutathione Peroxidase Activity. F1000Research (2022)

K BabaTC SuenV GoyalA StowieA DavidsonJ DeBruyneG Tosini

cone photoreceptor-likecircadian clockglutathione peroxidase activityoxidative stresscell linesystems biologycell biologychronobiology

“the Ubiquitin Ligase Siah2 is a Female-Specific Regulator of Circadian Rhythms and Metabolism”. PLoS Genetics (2022)

Tsedey MekbibTing-Chung SuenAisha Rollins-HairstonKiandra SmithAriel ArmstrongCloe GraySharon OwinoKenkichi BabaJulie E. BaggsJ. Christopher EhlenGianluca TosiniJason P. DeBruyne

geneticshuman geneticschronobiologyendocrinologymetabolic regulationfemale-specific regulatormolecular biologycircadian rhythmsepigeneticsmammalian biologymolecular regulationmetabolismphysiology

Maternal Ube3A Loss Disrupts Sleep Homeostasis but Leaves Circadian Rhythmicity Largely Intact. UNC Libraries (2021)

geneticsmaternal healthhomeostatic mechanismsdevelopmental biologypineal researchchronobiologysleep

Angelman Syndrome and Melatonin: What Can They Teach Us About Sleep Regulation. Journal of Pineal Research (2020)

angelman syndromesleep disorderssleep medicinemelatoninsleep regulationneurosciencepineal researchpsychiatrysleep

“a Novel Female-Specific Circadian Clock Mechanism Regulating Metabolism”. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Tsedey MekbibTing-Chung SuenAisha Rollins-HairstonKiandra SmithAriel ArmstrongCloe GraySharon OwinoKenkichi BabaJulie E. BaggsJ. Christopher EhlenGianluca TosiniJason P. DeBruyne

metabolismwomen's studiesmetabolic regulationsystems biologycryptochromeschronobiologyphysiology

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Jason DeBruyne

Associate Professor

Morehouse School of Medicine

Affiliations

Department of Pharmacology & Toxicology

MSM External Event Request Form

Pharmacology & Toxicology

Jason Debruyne is currently serving as a Pharmacology & Toxicology Associate Professor at Morehouse School of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jason DeBruyne

Morehouse School of Medicine

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bmal1 Deletion Alters Mitochondrial Microstructure and Function in Mouse Cone Photoreceptors. iScience (2025)

Retrospective Discrimination of Pnes and Epileptic Seizure Types Using Blood Rna Signatures. Journal of Neurology (2025)

Environmental Circadian Disruption Re-Writes Liver Circadian Proteomes. Nature Communications (2024)

Hao A DuongKenkichi BabaJason P DeBruyneAlec J DavidsonChristopher EhlenMichael PowellGianluca Tosini

hepatologyenvironmental scienceecologyliver physiologycircadian proteomessystems biologycryptochromeschronobiology

Environmental Circadian Disruption Re-Programs Liver Circadian Gene Expression. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Hao A. DuongKenkichi BabaJason P. DeBruyneAlec J. DavidsonChristopher EhlenMichael PowellGianluca Tosini

hepatologygene expressionenvironmental scienceliver physiologymolecular biologysystems biologycryptochromescircadian gene expressionchronobiology

Lysine-Independent Ubiquitination and Degradation of Rev-Erbα Involves a Bi-Functional Degradation Control Sequence at Its N-Terminus. bioRxiv (Cold Spring Harbor Laboratory) (2023)

The Circadian Clock Mediates the Response to Oxidative Stress in a Cone Photoreceptor‒Like (661W) Cell Line via Regulation of Glutathione Peroxidase Activity. F1000Research (2022)

K BabaTC SuenV GoyalA StowieA DavidsonJ DeBruyneG Tosini

cone photoreceptor-likecircadian clockglutathione peroxidase activityoxidative stresscell linesystems biologycell biologychronobiology

“the Ubiquitin Ligase Siah2 is a Female-Specific Regulator of Circadian Rhythms and Metabolism”. PLoS Genetics (2022)

Tsedey MekbibTing-Chung SuenAisha Rollins-HairstonKiandra SmithAriel ArmstrongCloe GraySharon OwinoKenkichi BabaJulie E. BaggsJ. Christopher EhlenGianluca TosiniJason P. DeBruyne

geneticshuman geneticschronobiologyendocrinologymetabolic regulationfemale-specific regulatormolecular biologycircadian rhythmsepigeneticsmammalian biologymolecular regulationmetabolismphysiology

Maternal Ube3A Loss Disrupts Sleep Homeostasis but Leaves Circadian Rhythmicity Largely Intact. UNC Libraries (2021)

geneticsmaternal healthhomeostatic mechanismsdevelopmental biologypineal researchchronobiologysleep

Angelman Syndrome and Melatonin: What Can They Teach Us About Sleep Regulation. Journal of Pineal Research (2020)

angelman syndromesleep disorderssleep medicinemelatoninsleep regulationneurosciencepineal researchpsychiatrysleep

“a Novel Female-Specific Circadian Clock Mechanism Regulating Metabolism”. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Tsedey MekbibTing-Chung SuenAisha Rollins-HairstonKiandra SmithAriel ArmstrongCloe GraySharon OwinoKenkichi BabaJulie E. BaggsJ. Christopher EhlenGianluca TosiniJason P. DeBruyne

metabolismwomen's studiesmetabolic regulationsystems biologycryptochromeschronobiologyphysiology

1
2
3
10 / page